======= C15orf26 ======= == Gene Information == * **Official Symbol**: CFAP161 * **Official Name**: cilia and flagella associated protein 161 * **Aliases and Previous Symbols**: N/A * **Entrez ID**: [[https://www.ncbi.nlm.nih.gov/gene/?term=161502|161502]] * **UniProt**: [[https://www.uniprot.org/uniprot/Q6P656|Q6P656]] * **Interactions**: [[https://thebiogrid.org/search.php?search=C15orf26&organism=9606|BioGRID]] * **PubMed articles**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20C15orf26|Open PubMed]] * **OMIM**: [[https://omim.org/entry/621378|Open OMIM]] == Function Summary == * **Entrez Summary**: N/A * **UniProt Summary**: May play a role in motile cilia function, possibly by acting on dynein arm assembly. {ECO:0000250|UniProtKB:Q568D2}. No Pfam Domain information is available for this gene. No GO term information is available for this gene. \\ === CRISPR Data === ^Screen^Score^ |[[:results:exp249|Vinorelbine 0.001μM R05 exp249]]|-2.09| |[[:results:exp312|2-Methoxyestradiol 0.55 to 1μM on day4 R07 exp312]]|-2.06| |[[:results:exp452|Azithromycin 100μM R08 exp452]]|-1.89| |[[:results:exp175|3-Bromopyruvate 7μM R04 exp175]]|-1.79| |[[:results:exp330|5-Azacytidine 2μM R07 exp330]]|1.77| No correlation found to any other genes in chemogenomics. Global Fraction of Cell Lines Where Essential: 0/739 ^Tissue^Fraction Of Cell Lines Where Essential^ |1290807.0|0/1| |909776.0|0/1| |bile duct|0/28| |blood|0/28| |bone|0/26| |breast|0/33| |central nervous system|0/56| |cervix|0/4| |colorectal|0/17| |esophagus|0/13| |fibroblast|0/1| |gastric|0/16| |kidney|0/21| |liver|0/20| |lung|0/75| |lymphocyte|0/16| |ovary|0/26| |pancreas|0/24| |peripheral nervous system|0/16| |plasma cell|0/15| |prostate|0/1| |skin|0/24| |soft tissue|0/9| |thyroid|0/2| |upper aerodigestive|0/22| |urinary tract|0/29| |uterus|0/5| == Essentiality in NALM6 == * **Essentiality Rank**: 7183 * **Expression level (log2 read counts)**: -4.6 {{:chemogenomics:nalm6 dist.png?nolink |}}