======= C2orf82 =======
== Gene Information ==
* **Official Symbol**: SNORC
* **Official Name**: secondary ossification center associated regulator of chondrocyte maturation
* **Aliases and Previous Symbols**: N/A
* **Entrez ID**: [[https://www.ncbi.nlm.nih.gov/gene/?term=389084|389084]]
* **UniProt**: [[https://www.uniprot.org/uniprot/Q6UX34|Q6UX34]]
* **Interactions**: [[https://thebiogrid.org/search.php?search=C2orf82&organism=9606|BioGRID]]
* **PubMed articles**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20C2orf82|Open PubMed]]
* **OMIM**: [[https://omim.org/entry/620882|Open OMIM]]
== Function Summary ==
* **Entrez Summary**: N/A
* **UniProt Summary**: Plays a role in the regulation of chondrocyte maturation and postnatal endochondral ossification. May inhibit cell growth stimulation induced by FGF2. {ECO:0000250|UniProtKB:Q9CXL7}.
No Pfam Domain information is available for this gene.
|cell periphery|
|cartilage development|
|connective tissue development|
|collagen-containing extracellular matrix|
|skeletal system development|
|tissue development|
\\
=== CRISPR Data ===
No hits were found.
No correlation found to any other genes in chemogenomics.
Global Fraction of Cell Lines Where Essential: 1/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|0/1|
|909776.0|0/1|
|bile duct|0/28|
|blood|0/28|
|bone|0/26|
|breast|0/33|
|central nervous system|0/56|
|cervix|0/4|
|colorectal|0/17|
|esophagus|0/13|
|fibroblast|0/1|
|gastric|0/16|
|kidney|0/21|
|liver|0/20|
|lung|0/75|
|lymphocyte|0/16|
|ovary|0/26|
|pancreas|0/24|
|peripheral nervous system|0/16|
|plasma cell|0/15|
|prostate|0/1|
|skin|0/24|
|soft tissue|0/9|
|thyroid|0/2|
|upper aerodigestive|0/22|
|urinary tract|0/29|
|uterus|0/5|
== Essentiality in NALM6 ==
* **Essentiality Rank**: 13307
* **Expression level (log2 read counts)**: 1.02
{{:chemogenomics:nalm6 dist.png?nolink |}}