======= CTAGE4 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: CTAGE4
  * **<color #00a2e8>Official Name</color>**: CTAGE family member 4
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=100128553|100128553]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q8IX94|Q8IX94]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=CTAGE4&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20CTAGE4|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: [[https://omim.org/entry/608910|Open OMIM]]

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**:  Tumor-associated antigen.

<button type='default' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
No Pfam Domain information is available for this gene.
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|vesicle cargo loading|
|endoplasmic reticulum exit site|
|protein secretion|
|establishment of protein localization to extracellular region|
|protein localization to extracellular region|
|peptide secretion|
|endoplasmic reticulum to Golgi vesicle-mediated transport|
|Golgi vesicle transport|
|cellular component|
|endoplasmic reticulum membrane|
|secretion by cell|
|export from cell|
|secretion|
|protein transport|
|intracellular transport|
|peptide transport|
|amide transport|
|establishment of protein localization|
|establishment of localization in cell|
|nitrogen compound transport|
|vesicle-mediated transport|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp401|SNS-032 25μM R07 exp401]]|-1.97|
|[[:results:exp132|Metformin 40μM R03 exp132]]|1.7|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:p:prim1|PRIM1]]|0.551|
|[[:human genes:c:chd4|CHD4]]|0.546|
|[[:human genes:p:psma6|PSMA6]]|0.51|
|[[:human genes:d:ddtl|DDTL]]|0.509|
|[[:human genes:g:golga6l1|GOLGA6L1]]|0.507|
|[[:human genes:t:tceb3c|TCEB3C]]|0.502|
|[[:human genes:p:psmb4|PSMB4]]|0.5|
|[[:human genes:c:ccna2|CCNA2]]|0.498|
|[[:human genes:p:pdcd11|PDCD11]]|0.487|
|[[:human genes:c:cbwd3|CBWD3]]|0.483|
|[[:human genes:m:mfsd12|MFSD12]]|0.483|
|[[:human genes:z:znf830|ZNF830]]|0.481|
|[[:human genes:t:tp53tg3c|TP53TG3C]]|0.48|
|[[:human genes:t:tp53tg3|TP53TG3]]|0.48|
|[[:human genes:t:tp53tg3b|TP53TG3B]]|0.48|
|[[:human genes:s:slc6a17|SLC6A17]]|0.474|
|[[:human genes:n:nol10|NOL10]]|0.474|
|[[:human genes:t:tbc1d3f|TBC1D3F]]|0.474|
|[[:human genes:r:rpl35|RPL35]]|0.472|
|[[:human genes:t:tbc1d3g|TBC1D3G]]|0.469|
|[[:human genes:t:tceb3cl|TCEB3CL]]|0.467|
|[[:human genes:p:polr2d|POLR2D]]|0.466|
|[[:human genes:c:copg1|COPG1]]|0.464|
|[[:human genes:s:syt9|SYT9]]|0.464|
|[[:human genes:g:golga6l3|GOLGA6L3]]|0.464|
|[[:human genes:t:tsg101|TSG101]]|0.458|
|[[:human genes:s:ssh2|SSH2]]|0.458|
|[[:human genes:p:psmd2|PSMD2]]|0.457|
|[[:human genes:t:tbc1d3h|TBC1D3H]]|0.456|
|[[:human genes:a:atp6v1b2|ATP6V1B2]]|0.455|
|[[:human genes:v:vps28|VPS28]]|0.455|
|[[:human genes:d:dhx38|DHX38]]|0.454|
|[[:human genes:a:atp6v1a|ATP6V1A]]|0.452|
|[[:human genes:s:sart1|SART1]]|0.451|
|[[:human genes:a:atp6v1c1|ATP6V1C1]]|0.451|
|[[:human genes:w:wdr75|WDR75]]|0.451|
|[[:human genes:c:cbwd6|CBWD6]]|0.45|
|[[:human genes:l:lrr1|LRR1]]|0.449|
|[[:human genes:t:tspy1|TSPY1]]|0.447|
|[[:human genes:i:ik|IK]]|0.447|
|[[:human genes:c:cbwd5|CBWD5]]|0.445|
|[[:human genes:r:rpl6|RPL6]]|0.444|
|[[:human genes:s:supt6h|SUPT6H]]|0.443|
|[[:human genes:r:rrp7a|RRP7A]]|0.443|
|[[:human genes:r:rps12|RPS12]]|0.443|
|[[:human genes:c:c1qtnf9b|C1QTNF9B]]|0.443|
|[[:human genes:c:chaf1a|CHAF1A]]|0.442|
|[[:human genes:p:psmc1|PSMC1]]|0.442|
|[[:human genes:p:pola2|POLA2]]|0.442|
|[[:human genes:d:ddt|DDT]]|0.44|
|[[:human genes:t:tceb3cl2|TCEB3CL2]]|0.44|
|[[:human genes:p:psmc2|PSMC2]]|0.44|
|[[:human genes:g:golga6l6|GOLGA6L6]]|0.439|
|[[:human genes:d:dtl|DTL]]|0.437|
|[[:human genes:g:golga8o|GOLGA8O]]|0.436|
|[[:human genes:r:rrp15|RRP15]]|0.436|
|[[:human genes:c:cope|COPE]]|0.436|
|[[:human genes:u:utp3|UTP3]]|0.435|
|[[:human genes:r:rnpc3|RNPC3]]|0.434|
|[[:human genes:a:aatf|AATF]]|0.432|
|[[:human genes:r:rad51|RAD51]]|0.432|
|[[:human genes:o:orc6|ORC6]]|0.431|
|[[:human genes:c:chmp4b|CHMP4B]]|0.429|
|[[:human genes:d:ddx21|DDX21]]|0.429|
|[[:human genes:n:nup93|NUP93]]|0.429|
|[[:human genes:c:cep192|CEP192]]|0.428|
|[[:human genes:p:pla2g4f|PLA2G4F]]|0.428|
|[[:human genes:e:exosc9|EXOSC9]]|0.428|
|[[:human genes:p:polr2a|POLR2A]]|0.428|
|[[:human genes:n:nbpf10|NBPF10]]|0.428|
|[[:human genes:r:rps2|RPS2]]|0.427|
|[[:human genes:d:ddx56|DDX56]]|0.427|
|[[:human genes:e:exosc6|EXOSC6]]|0.424|
|[[:human genes:k:kiaa0947|KIAA0947]]|0.424|
|[[:human genes:h:hivep3|HIVEP3]]|0.423|
|[[:human genes:o:osbp|OSBP]]|0.423|
|[[:human genes:i:igfn1|IGFN1]]|0.422|
|[[:human genes:s:sf3a3|SF3A3]]|0.421|
|[[:human genes:t:tp53tg3d|TP53TG3D]]|0.42|
|[[:human genes:u:upf1|UPF1]]|0.42|
|[[:human genes:p:psmb3|PSMB3]]|0.418|
|[[:human genes:s:sult2b1|SULT2B1]]|0.418|
|[[:human genes:p:pan3|PAN3]]|0.417|
|[[:human genes:o:orc1|ORC1]]|0.417|
|[[:human genes:c:cdc5l|CDC5L]]|0.417|
|[[:human genes:m:mt1e|MT1E]]|0.416|
|[[:human genes:t:tuba8|TUBA8]]|0.415|
|[[:human genes:p:psmd7|PSMD7]]|0.414|
|[[:human genes:a:ankle2|ANKLE2]]|0.413|
|[[:human genes:c:col2a1|COL2A1]]|0.413|
|[[:human genes:c:c2orf27a|C2orf27A]]|0.412|
|[[:human genes:p:psmd3|PSMD3]]|0.411|
|[[:human genes:t:ticrr|TICRR]]|0.411|
|[[:human genes:p:psma7|PSMA7]]|0.411|
|[[:human genes:n:nsf|NSF]]|0.41|
|[[:human genes:s:sf3a2|SF3A2]]|0.41|
|[[:human genes:n:nol12|NOL12]]|0.41|
|[[:human genes:p:psmb2|PSMB2]]|0.408|
|[[:human genes:s:sec13|SEC13]]|0.408|
|[[:human genes:c:cdt1|CDT1]]|0.407|
|[[:human genes:a:acsf2|ACSF2]]|0.407|
|[[:human genes:f:fam160a1|FAM160A1]]|0.407|
|[[:human genes:n:numa1|NUMA1]]|0.406|
|[[:human genes:s:scgb1c1|SCGB1C1]]|0.404|
|[[:human genes:t:twistnb|TWISTNB]]|0.404|
|[[:human genes:h:hgc6.3|HGC6.3]]|0.403|
|[[:human genes:p:pdcd7|PDCD7]]|0.403|
|[[:human genes:d:dimt1|DIMT1]]|0.402|
|[[:human genes:p:psmc5|PSMC5]]|0.402|
|[[:human genes:w:wdr43|WDR43]]|0.401|
|[[:human genes:r:rps7|RPS7]]|0.401|
|[[:human genes:r:rps3a|RPS3A]]|0.4|
|[[:human genes:n:ncl|NCL]]|0.4|
|[[:human genes:a:atp6v0b|ATP6V0B]]|0.4|
|[[:human genes:a:aqr|AQR]]|0.4|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 0/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|0/1|
|909776.0|0/1|
|bile duct|0/28|
|blood|0/28|
|bone|0/26|
|breast|0/33|
|central nervous system|0/56|
|cervix|0/4|
|colorectal|0/17|
|esophagus|0/13|
|fibroblast|0/1|
|gastric|0/16|
|kidney|0/21|
|liver|0/20|
|lung|0/75|
|lymphocyte|0/16|
|ovary|0/26|
|pancreas|0/24|
|peripheral nervous system|0/16|
|plasma cell|0/15|
|prostate|0/1|
|skin|0/24|
|soft tissue|0/9|
|thyroid|0/2|
|upper aerodigestive|0/22|
|urinary tract|0/29|
|uterus|0/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 1866
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: -1.98 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='CTAGE4 Expression in NALM6 Cells: -1.98'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>