======= CTTNBP2NL ======= == Gene Information == * **Official Symbol**: CTTNBP2NL * **Official Name**: CTTNBP2 N-terminal like * **Aliases and Previous Symbols**: N/A * **Entrez ID**: [[https://www.ncbi.nlm.nih.gov/gene/?term=55917|55917]] * **UniProt**: [[https://www.uniprot.org/uniprot/Q9P2B4|Q9P2B4]] * **Interactions**: [[https://thebiogrid.org/search.php?search=CTTNBP2NL&organism=9606|BioGRID]] * **PubMed articles**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20CTTNBP2NL|Open PubMed]] * **OMIM**: [[https://omim.org/entry/615100|Open OMIM]] == Function Summary == * **Entrez Summary**: N/A * **UniProt Summary**: N/A |CortBP2| |protein phosphatase 2A binding| |negative regulation of transporter activity| |negative regulation of transmembrane transport| |protein dephosphorylation| |actin cytoskeleton| |regulation of transporter activity| |dephosphorylation| |negative regulation of transport| |regulation of transmembrane transport| |negative regulation of molecular function| |regulation of transport| \\ === CRISPR Data === ^Screen^Score^ |[[:results:exp130|JQ1 0.01μM R03 exp130]]|-1.97| |[[:results:exp473|Cincreasin 100μM R08 exp473]]|1.79| |[[:results:exp342|Calcium Ionophore 0.4μM R07 exp342]]|1.96| No correlation found to any other genes in chemogenomics. Global Fraction of Cell Lines Where Essential: 0/739 ^Tissue^Fraction Of Cell Lines Where Essential^ |1290807.0|0/1| |909776.0|0/1| |bile duct|0/28| |blood|0/28| |bone|0/26| |breast|0/33| |central nervous system|0/56| |cervix|0/4| |colorectal|0/17| |esophagus|0/13| |fibroblast|0/1| |gastric|0/16| |kidney|0/21| |liver|0/20| |lung|0/75| |lymphocyte|0/16| |ovary|0/26| |pancreas|0/24| |peripheral nervous system|0/16| |plasma cell|0/15| |prostate|0/1| |skin|0/24| |soft tissue|0/9| |thyroid|0/2| |upper aerodigestive|0/22| |urinary tract|0/29| |uterus|0/5| == Essentiality in NALM6 == * **Essentiality Rank**: 7522 * **Expression level (log2 read counts)**: 3.22 {{:chemogenomics:nalm6 dist.png?nolink |}}