======= DISP2 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: DISP2
  * **<color #00a2e8>Official Name</color>**: dispatched RND transporter family member 2
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=85455|85455]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/A7MBM2|A7MBM2]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=DISP2&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20DISP2|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: [[https://omim.org/entry/607503|Open OMIM]]

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='default' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
No Pfam Domain information is available for this gene.
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|smoothened signaling pathway|
|cellular component|
|molecular function|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp215|Colchicine 0.009μM R05 exp215]]|1.76|
|[[:results:exp156|UNC2400 2μM R03 exp156]]|1.77|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:c:chd4|CHD4]]|0.568|
|[[:human genes:c:copa|COPA]]|0.548|
|[[:human genes:a:atp1a3|ATP1A3]]|0.541|
|[[:human genes:r:rrm1|RRM1]]|0.537|
|[[:human genes:c:cbwd3|CBWD3]]|0.528|
|[[:human genes:c:c14orf93|C14orf93]]|0.517|
|[[:human genes:n:npipb5|NPIPB5]]|0.516|
|[[:human genes:c:cbwd5|CBWD5]]|0.514|
|[[:human genes:c:copg1|COPG1]]|0.512|
|[[:human genes:k:kif3c|KIF3C]]|0.508|
|[[:human genes:p:pan3|PAN3]]|0.498|
|[[:human genes:p:psmb4|PSMB4]]|0.497|
|[[:human genes:c:ccna2|CCNA2]]|0.496|
|[[:human genes:t:tceb3c|TCEB3C]]|0.495|
|[[:human genes:u:utp3|UTP3]]|0.492|
|[[:human genes:d:ddtl|DDTL]]|0.492|
|[[:human genes:m:myt1l|MYT1L]]|0.492|
|[[:human genes:p:pcf11|PCF11]]|0.49|
|[[:human genes:a:aatf|AATF]]|0.488|
|[[:human genes:a:aqr|AQR]]|0.488|
|[[:human genes:t:tceb3cl2|TCEB3CL2]]|0.487|
|[[:human genes:r:rpl30|RPL30]]|0.485|
|[[:human genes:o:orc1|ORC1]]|0.485|
|[[:human genes:v:vasn|VASN]]|0.485|
|[[:human genes:p:pan2|PAN2]]|0.482|
|[[:human genes:t:tceb3cl|TCEB3CL]]|0.481|
|[[:human genes:e:exosc5|EXOSC5]]|0.481|
|[[:human genes:c:ccdc64b|CCDC64B]]|0.481|
|[[:human genes:s:smg1|SMG1]]|0.48|
|[[:human genes:c:cbwd6|CBWD6]]|0.478|
|[[:human genes:a:aamp|AAMP]]|0.478|
|[[:human genes:o:ogfr|OGFR]]|0.475|
|[[:human genes:t:tfip11|TFIP11]]|0.473|
|[[:human genes:c:c1qtnf9b|C1QTNF9B]]|0.473|
|[[:human genes:n:napa|NAPA]]|0.471|
|[[:human genes:r:rad51|RAD51]]|0.469|
|[[:human genes:s:slc4a1|SLC4A1]]|0.465|
|[[:human genes:t:tbc1d3h|TBC1D3H]]|0.463|
|[[:human genes:r:ranbp2|RANBP2]]|0.462|
|[[:human genes:n:nop16|NOP16]]|0.461|
|[[:human genes:a:ankle2|ANKLE2]]|0.461|
|[[:human genes:n:narfl|NARFL]]|0.459|
|[[:human genes:m:med14|MED14]]|0.458|
|[[:human genes:e:ebna1bp2|EBNA1BP2]]|0.458|
|[[:human genes:p:ppm1d|PPM1D]]|0.458|
|[[:human genes:r:rbbp5|RBBP5]]|0.457|
|[[:human genes:r:rpl9|RPL9]]|0.457|
|[[:human genes:t:tbc1d3f|TBC1D3F]]|0.456|
|[[:human genes:d:dtl|DTL]]|0.455|
|[[:human genes:z:zfand5|ZFAND5]]|0.455|
|[[:human genes:h:hist2h3c|HIST2H3C]]|0.454|
|[[:human genes:h:hist2h3a|HIST2H3A]]|0.454|
|[[:human genes:c:chchd3|CHCHD3]]|0.453|
|[[:human genes:p:polr2d|POLR2D]]|0.453|
|[[:human genes:s:supt5h|SUPT5H]]|0.452|
|[[:human genes:h:hist2h2bf|HIST2H2BF]]|0.452|
|[[:human genes:s:snrpa1|SNRPA1]]|0.451|
|[[:human genes:t:tbc1d3g|TBC1D3G]]|0.45|
|[[:human genes:a:acbd4|ACBD4]]|0.45|
|[[:human genes:a:atp13a1|ATP13A1]]|0.45|
|[[:human genes:z:znf541|ZNF541]]|0.449|
|[[:human genes:n:nol12|NOL12]]|0.448|
|[[:human genes:r:rps12|RPS12]]|0.448|
|[[:human genes:t:tbc1d3c|TBC1D3C]]|0.447|
|[[:human genes:s:sec13|SEC13]]|0.447|
|[[:human genes:h:hnrnpa1|HNRNPA1]]|0.446|
|[[:human genes:m:mt1e|MT1E]]|0.446|
|[[:human genes:k:kctd17|KCTD17]]|0.446|
|[[:human genes:p:psmd11|PSMD11]]|0.445|
|[[:human genes:h:hap1|HAP1]]|0.444|
|[[:human genes:n:numa1|NUMA1]]|0.444|
|[[:human genes:i:ik|IK]]|0.444|
|[[:human genes:p:psmc6|PSMC6]]|0.444|
|[[:human genes:r:rps19|RPS19]]|0.443|
|[[:human genes:t:terf1|TERF1]]|0.442|
|[[:human genes:c:cdc7|CDC7]]|0.441|
|[[:human genes:a:ankle1|ANKLE1]]|0.44|
|[[:human genes:g:golga6l3|GOLGA6L3]]|0.438|
|[[:human genes:s:snip1|SNIP1]]|0.438|
|[[:human genes:t:twistnb|TWISTNB]]|0.436|
|[[:human genes:m:mbtd1|MBTD1]]|0.436|
|[[:human genes:p:psmc2|PSMC2]]|0.435|
|[[:human genes:p:psmd1|PSMD1]]|0.434|
|[[:human genes:s:supt6h|SUPT6H]]|0.432|
|[[:human genes:g:golga8o|GOLGA8O]]|0.431|
|[[:human genes:m:myo1h|MYO1H]]|0.431|
|[[:human genes:n:nsf|NSF]]|0.43|
|[[:human genes:t:tsg101|TSG101]]|0.429|
|[[:human genes:e:exosc9|EXOSC9]]|0.429|
|[[:human genes:i:igfn1|IGFN1]]|0.428|
|[[:human genes:c:cdc45|CDC45]]|0.426|
|[[:human genes:c:cmya5|CMYA5]]|0.426|
|[[:human genes:s:smg7|SMG7]]|0.426|
|[[:human genes:c:cdca3|CDCA3]]|0.426|
|[[:human genes:r:rps2|RPS2]]|0.425|
|[[:human genes:v:vps54|VPS54]]|0.425|
|[[:human genes:t:ttc1|TTC1]]|0.425|
|[[:human genes:p:pola1|POLA1]]|0.421|
|[[:human genes:n:nup205|NUP205]]|0.42|
|[[:human genes:p:pole|POLE]]|0.42|
|[[:human genes:g:gprin2|GPRIN2]]|0.42|
|[[:human genes:r:rps20|RPS20]]|0.419|
|[[:human genes:p:polr2f|POLR2F]]|0.419|
|[[:human genes:d:dock6|DOCK6]]|0.419|
|[[:human genes:v:vps28|VPS28]]|0.418|
|[[:human genes:f:fcn2|FCN2]]|0.418|
|[[:human genes:f:fam160a1|FAM160A1]]|0.417|
|[[:human genes:s:sf3a1|SF3A1]]|0.417|
|[[:human genes:r:rrp7a|RRP7A]]|0.416|
|[[:human genes:h:hivep3|HIVEP3]]|0.416|
|[[:human genes:a:akt1s1|AKT1S1]]|0.416|
|[[:human genes:g:golga6l4|GOLGA6L4]]|0.416|
|[[:human genes:u:usp35|USP35]]|0.416|
|[[:human genes:r:rps7|RPS7]]|0.415|
|[[:human genes:o:orc6|ORC6]]|0.414|
|[[:human genes:h:hk1|HK1]]|0.414|
|[[:human genes:w:wdr87|WDR87]]|0.413|
|[[:human genes:t:tbc1d3|TBC1D3]]|0.413|
|[[:human genes:r:rpsa|RPSA]]|0.412|
|[[:human genes:s:scgb1c1|SCGB1C1]]|0.412|
|[[:human genes:t:tspy8|TSPY8]]|0.412|
|[[:human genes:a:atxn1|ATXN1]]|0.411|
|[[:human genes:h:hist1h4b|HIST1H4B]]|0.411|
|[[:human genes:e:exosc6|EXOSC6]]|0.41|
|[[:human genes:c:cdh24|CDH24]]|0.41|
|[[:human genes:c:ccdc116|CCDC116]]|0.409|
|[[:human genes:r:rnpc3|RNPC3]]|0.408|
|[[:human genes:t:ticrr|TICRR]]|0.407|
|[[:human genes:b:bysl|BYSL]]|0.407|
|[[:human genes:r:rrn3|RRN3]]|0.407|
|[[:human genes:c:chst3|CHST3]]|0.406|
|[[:human genes:g:gid4|GID4]]|0.406|
|[[:human genes:t:tp53tg3b|TP53TG3B]]|0.403|
|[[:human genes:r:rps3a|RPS3A]]|0.402|
|[[:human genes:f:fbxw9|FBXW9]]|0.402|
|[[:human genes:t:tp53tg3|TP53TG3]]|0.402|
|[[:human genes:t:tyms|TYMS]]|0.402|
|[[:human genes:m:med17|MED17]]|0.402|
|[[:human genes:t:tuba8|TUBA8]]|0.401|
|[[:human genes:c:cep192|CEP192]]|0.401|
|[[:human genes:p:psma6|PSMA6]]|0.401|
|[[:human genes:t:tp53tg3c|TP53TG3C]]|0.401|
|[[:human genes:s:slc6a17|SLC6A17]]|0.4|
|[[:human genes:r:rpl35|RPL35]]|0.4|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 0/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|0/1|
|909776.0|0/1|
|bile duct|0/28|
|blood|0/28|
|bone|0/26|
|breast|0/33|
|central nervous system|0/56|
|cervix|0/4|
|colorectal|0/17|
|esophagus|0/13|
|fibroblast|0/1|
|gastric|0/16|
|kidney|0/21|
|liver|0/20|
|lung|0/75|
|lymphocyte|0/16|
|ovary|0/26|
|pancreas|0/24|
|peripheral nervous system|0/16|
|plasma cell|0/15|
|prostate|0/1|
|skin|0/24|
|soft tissue|0/9|
|thyroid|0/2|
|upper aerodigestive|0/22|
|urinary tract|0/29|
|uterus|0/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 1981
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 4.4 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='DISP2 Expression in NALM6 Cells: 4.4'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>