======= EEF1B2 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: EEF1B2
  * **<color #00a2e8>Official Name</color>**: eukaryotic translation elongation factor 1 beta 2
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=1933|1933]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/P24534|P24534]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=EEF1B2&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20EEF1B2|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: [[https://omim.org/entry/600655|Open OMIM]]

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**:  EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.

<button type='primary' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
|EF1 GNE|
|EF-1 beta acid|
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|eukaryotic translation elongation factor 1 complex|
|translation elongation factor activity|
|guanyl-nucleotide exchange factor activity|
|translational elongation|
|translation|
|peptide biosynthetic process|
|amide biosynthetic process|
|peptide metabolic process|
|cellular amide metabolic process|
|endoplasmic reticulum|
|organonitrogen compound biosynthetic process|
|cellular nitrogen compound biosynthetic process|
|cellular macromolecule biosynthetic process|
|macromolecule biosynthetic process|
|gene expression|
</modal>
\\

 === CRISPR Data ===
<button type='default' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='default' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
No hits were found.
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
No correlation found to any other genes in chemogenomics.
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 63/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|0/1|
|909776.0|0/1|
|bile duct|3/28|
|blood|1/28|
|bone|4/26|
|breast|5/33|
|central nervous system|4/56|
|cervix|0/4|
|colorectal|5/17|
|esophagus|2/13|
|fibroblast|0/1|
|gastric|0/16|
|kidney|2/21|
|liver|2/20|
|lung|8/75|
|lymphocyte|1/16|
|ovary|1/26|
|pancreas|4/24|
|peripheral nervous system|4/16|
|plasma cell|2/15|
|prostate|0/1|
|skin|0/24|
|soft tissue|1/9|
|thyroid|0/2|
|upper aerodigestive|3/22|
|urinary tract|1/29|
|uterus|0/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 4834
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 8.39 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='EEF1B2 Expression in NALM6 Cells: 8.39'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>