======= ELMSAN1 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: MIDEAS
  * **<color #00a2e8>Official Name</color>**: mitotic deacetylase associated SANT domain protein
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=91748|91748]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q6PJG2|Q6PJG2]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=ELMSAN1&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20ELMSAN1|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: [[https://omim.org/entry/621074|Open OMIM]]

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='primary' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
|ELM2|
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|histone deacetylase complex|
|transcription factor complex|
|transcription regulatory region DNA binding|
|transcription factor binding|
|DNA-binding transcription factor activity|
|DNA-binding transcription factor activity, RNA polymerase II-specific|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp517|Quercetin 20μM R08 exp517]]|-2.43|
|[[:results:exp67|BVD-523 15μM R02 exp67]]|-2.33|
|[[:results:exp217|Mdivi-1 15μM R05 exp217]]|-2.21|
|[[:results:exp401|SNS-032 25μM R07 exp401]]|-2.13|
|[[:results:exp460|BML-284 0.09μM R08 exp460]]|-2.08|
|[[:results:exp58|UM131593 0.1μM R01 exp58]]|-2.07|
|[[:results:exp454|Bafilomycin-A1 0.009μM R08 exp454]]|-2.03|
|[[:results:exp357|Dorsomorphin 5μM R07 exp357]]|-2.03|
|[[:results:exp106|UM131593 0.2μM R03 exp106]]|-1.95|
|[[:results:exp440|Aphidicolin 0.4μM R08 exp440]]|-1.92|
|[[:results:exp27|Pimelic-diphenylamide-106 0.5μM R00 exp27]]|-1.79|
|[[:results:exp224|CB-839 10μM R05 exp224]]|-1.78|
|[[:results:exp329|Hydroxyurea 100μM R07 exp329]]|-1.76|
|[[:results:exp175|3-Bromopyruvate 7μM R04 exp175]]|-1.75|
|[[:results:exp141|Nifurtimox 1μM R03 exp141]]|-1.72|
|[[:results:exp124|GSK343 3μM R03 exp124]]|-1.71|
|[[:results:exp59|UMK57 1μM R01 exp59]]|-1.71|
|[[:results:exp3|Actinomycin-D 0.001μM R00 exp3]]|-1.7|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:a:anp32a|ANP32A]]|0.408|
|[[:human genes:i:ipo9|IPO9]]|0.408|
|[[:human genes:d:dnttip1|DNTTIP1]]|0.404|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 0/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|0/1|
|909776.0|0/1|
|bile duct|0/28|
|blood|0/28|
|bone|0/26|
|breast|0/33|
|central nervous system|0/56|
|cervix|0/4|
|colorectal|0/17|
|esophagus|0/13|
|fibroblast|0/1|
|gastric|0/16|
|kidney|0/21|
|liver|0/20|
|lung|0/75|
|lymphocyte|0/16|
|ovary|0/26|
|pancreas|0/24|
|peripheral nervous system|0/16|
|plasma cell|0/15|
|prostate|0/1|
|skin|0/24|
|soft tissue|0/9|
|thyroid|0/2|
|upper aerodigestive|0/22|
|urinary tract|0/29|
|uterus|0/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 12927
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 6.45 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='ELMSAN1 Expression in NALM6 Cells: 6.45'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>