======= GOLGA6L1 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: GOLGA6L1
  * **<color #00a2e8>Official Name</color>**: golgin A6 family like 1
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=283767|283767]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q8N7Z2|Q8N7Z2]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=GOLGA6L1&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20GOLGA6L1|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**:  N/A

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='default' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='default' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
No Pfam Domain information is available for this gene.
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
No GO term information is available for this gene.
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp34|Rotenone 20μM R00 exp34]]|-3.57|
|[[:results:exp20|Etoposide 10μM R00 exp20]]|-3.4|
|[[:results:exp24|Nocodazole 0.2μM R00 exp24]]|-3.34|
|[[:results:exp2|5-Fluorouracil 20μM R00 exp2]]|-3.06|
|[[:results:exp4|Actinomycin-D 0.01μM R00 exp4]]|-2.63|
|[[:results:exp28|Pimelic-diphenylamide-106 5μM R00 exp28]]|-2.56|
|[[:results:exp531|THZ1 0.06μM R08 exp531]]|-2.56|
|[[:results:exp469|CFI-400945 25μM R08 exp469]]|-2.49|
|[[:results:exp3|Actinomycin-D 0.001μM R00 exp3]]|-2.42|
|[[:results:exp26|Oligomycin-A 20μM R00 exp26]]|-2.29|
|[[:results:exp19|Etoposide 1μM R00 exp19]]|-2.23|
|[[:results:exp448|Ammonium tetrathiomolybdate 10μM R08 exp448]]|-2.16|
|[[:results:exp474|CR131-b 0.005μM R08 exp474]]|-2.15|
|[[:results:exp487|Hinokiflavone 12μM R08 exp487]]|-2.02|
|[[:results:exp451|Atovaquone 15μM R08 exp451]]|-1.95|
|[[:results:exp33|Rotenone 2μM R00 exp33]]|-1.95|
|[[:results:exp497|Lead acetate 2000μM R08 exp497]]|-1.93|
|[[:results:exp466|Cannabidiol 20μM R08 exp466]]|-1.86|
|[[:results:exp8|Brefeldin A 0.02μM R00 exp8]]|-1.78|
|[[:results:exp22|MLN-4924 2μM R00 exp22]]|-1.71|
|[[:results:exp17|DABN 20μM R00 exp17]]|-1.7|
|[[:results:exp516|Pyrazinamide 100μM R08 exp516]]|1.82|
|[[:results:exp506|Momordin-Ic 10μM R08 exp506]]|1.97|
|[[:results:exp444|THZ531 0.225μM R08 exp444]]|2.03|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:p:polr2j3|POLR2J3]]|0.739|
|[[:human genes:p:pcna|PCNA]]|0.708|
|[[:human genes:n:npipb3|NPIPB3]]|0.7|
|[[:human genes:k:kri1|KRI1]]|0.644|
|[[:human genes:r:rpl37a|RPL37A]]|0.6|
|[[:human genes:t:taf1|TAF1]]|0.598|
|[[:human genes:e:exosc9|EXOSC9]]|0.579|
|[[:human genes:t:tceb3c|TCEB3C]]|0.577|
|[[:human genes:c:cdt1|CDT1]]|0.572|
|[[:human genes:t:tceb3cl|TCEB3CL]]|0.567|
|[[:human genes:p:prim1|PRIM1]]|0.562|
|[[:human genes:p:paf1|PAF1]]|0.556|
|[[:human genes:t:tceb3cl2|TCEB3CL2]]|0.556|
|[[:human genes:e:eif3g|EIF3G]]|0.555|
|[[:human genes:n:nol12|NOL12]]|0.555|
|[[:human genes:c:ctage9|CTAGE9]]|0.555|
|[[:human genes:r:rpl17|RPL17]]|0.555|
|[[:human genes:r:rpl23a|RPL23A]]|0.552|
|[[:human genes:c:ccna2|CCNA2]]|0.552|
|[[:human genes:p:polr2i|POLR2I]]|0.551|
|[[:human genes:u:utp3|UTP3]]|0.55|
|[[:human genes:m:mphosph10|MPHOSPH10]]|0.547|
|[[:human genes:g:gnl3l|GNL3L]]|0.542|
|[[:human genes:c:chrna2|CHRNA2]]|0.536|
|[[:human genes:a:atp6v1a|ATP6V1A]]|0.534|
|[[:human genes:r:rps10|RPS10]]|0.533|
|[[:human genes:p:psmb4|PSMB4]]|0.531|
|[[:human genes:a:atp6ap1|ATP6AP1]]|0.528|
|[[:human genes:i:ik|IK]]|0.527|
|[[:human genes:r:rpl30|RPL30]]|0.526|
|[[:human genes:a:aatf|AATF]]|0.526|
|[[:human genes:c:cdh24|CDH24]]|0.522|
|[[:human genes:t:taf15|TAF15]]|0.521|
|[[:human genes:u:usp37|USP37]]|0.516|
|[[:human genes:r:rpl6|RPL6]]|0.516|
|[[:human genes:r:rpl7a|RPL7A]]|0.514|
|[[:human genes:t:tpx2|TPX2]]|0.514|
|[[:human genes:c:cox7a2l|COX7A2L]]|0.51|
|[[:human genes:n:nol10|NOL10]]|0.51|
|[[:human genes:t:tfrc|TFRC]]|0.508|
|[[:human genes:v:vps28|VPS28]]|0.508|
|[[:human genes:c:ctage4|CTAGE4]]|0.507|
|[[:human genes:r:rpl23|RPL23]]|0.506|
|[[:human genes:r:rpl15|RPL15]]|0.505|
|[[:human genes:p:pcgf1|PCGF1]]|0.503|
|[[:human genes:d:ddx56|DDX56]]|0.501|
|[[:human genes:p:pes1|PES1]]|0.499|
|[[:human genes:r:rrp1|RRP1]]|0.497|
|[[:human genes:z:znf687|ZNF687]]|0.497|
|[[:human genes:k:krt78|KRT78]]|0.495|
|[[:human genes:t:tyms|TYMS]]|0.493|
|[[:human genes:i:il2rb|IL2RB]]|0.492|
|[[:human genes:n:nol6|NOL6]]|0.491|
|[[:human genes:r:rps19|RPS19]]|0.49|
|[[:human genes:r:rps9|RPS9]]|0.49|
|[[:human genes:c:cep192|CEP192]]|0.49|
|[[:human genes:i:igfn1|IGFN1]]|0.489|
|[[:human genes:n:nop16|NOP16]]|0.488|
|[[:human genes:p:polr2a|POLR2A]]|0.486|
|[[:human genes:f:fam231a|FAM231A]]|0.485|
|[[:human genes:f:fam231c|FAM231C]]|0.485|
|[[:human genes:o:orc6|ORC6]]|0.485|
|[[:human genes:d:dido1|DIDO1]]|0.482|
|[[:human genes:p:pole|POLE]]|0.48|
|[[:human genes:b:bcor|BCOR]]|0.479|
|[[:human genes:s:ssx3|SSX3]]|0.477|
|[[:human genes:k:kiaa0947|KIAA0947]]|0.477|
|[[:human genes:r:rpl35|RPL35]]|0.474|
|[[:human genes:t:tspy2|TSPY2]]|0.474|
|[[:human genes:t:tbc1d3h|TBC1D3H]]|0.472|
|[[:human genes:t:tspy1|TSPY1]]|0.469|
|[[:human genes:u:upf1|UPF1]]|0.469|
|[[:human genes:e:exosc7|EXOSC7]]|0.468|
|[[:human genes:s:snrpf|SNRPF]]|0.467|
|[[:human genes:n:noc4l|NOC4L]]|0.463|
|[[:human genes:b:brd2|BRD2]]|0.463|
|[[:human genes:p:pdcd11|PDCD11]]|0.462|
|[[:human genes:a:adrm1|ADRM1]]|0.462|
|[[:human genes:t:tsg101|TSG101]]|0.46|
|[[:human genes:p:pan3|PAN3]]|0.46|
|[[:human genes:c:celf6|CELF6]]|0.459|
|[[:human genes:r:rps12|RPS12]]|0.459|
|[[:human genes:t:tp53tg3d|TP53TG3D]]|0.458|
|[[:human genes:f:fam20a|FAM20A]]|0.458|
|[[:human genes:r:rps2|RPS2]]|0.458|
|[[:human genes:t:tspy8|TSPY8]]|0.457|
|[[:human genes:s:slc6a17|SLC6A17]]|0.457|
|[[:human genes:a:aamp|AAMP]]|0.456|
|[[:human genes:a:aurka|AURKA]]|0.456|
|[[:human genes:e:exd1|EXD1]]|0.456|
|[[:human genes:c:col2a1|COL2A1]]|0.454|
|[[:human genes:a:atp6v0c|ATP6V0C]]|0.453|
|[[:human genes:n:nip7|NIP7]]|0.453|
|[[:human genes:t:ticrr|TICRR]]|0.452|
|[[:human genes:r:rplp1|RPLP1]]|0.452|
|[[:human genes:a:atp6v1c1|ATP6V1C1]]|0.451|
|[[:human genes:c:cebpz|CEBPZ]]|0.449|
|[[:human genes:r:rpl36|RPL36]]|0.448|
|[[:human genes:c:ccdc116|CCDC116]]|0.446|
|[[:human genes:m:mdn1|MDN1]]|0.446|
|[[:human genes:p:pold1|POLD1]]|0.446|
|[[:human genes:s:sh3bp1|SH3BP1]]|0.446|
|[[:human genes:g:golga8o|GOLGA8O]]|0.445|
|[[:human genes:r:rad51|RAD51]]|0.444|
|[[:human genes:p:psmd8|PSMD8]]|0.444|
|[[:human genes:n:narfl|NARFL]]|0.443|
|[[:human genes:r:rps7|RPS7]]|0.443|
|[[:human genes:n:npipb5|NPIPB5]]|0.442|
|[[:human genes:p:psmd2|PSMD2]]|0.442|
|[[:human genes:n:ngdn|NGDN]]|0.442|
|[[:human genes:o:orc1|ORC1]]|0.442|
|[[:human genes:c:cdc6|CDC6]]|0.44|
|[[:human genes:b:bysl|BYSL]]|0.44|
|[[:human genes:d:ddx3x|DDX3X]]|0.439|
|[[:human genes:c:copb1|COPB1]]|0.438|
|[[:human genes:p:ppan|PPAN]]|0.437|
|[[:human genes:c:copg1|COPG1]]|0.436|
|[[:human genes:m:mgme1|MGME1]]|0.435|
|[[:human genes:r:ring1|RING1]]|0.435|
|[[:human genes:p:pcf11|PCF11]]|0.434|
|[[:human genes:t:timeless|TIMELESS]]|0.434|
|[[:human genes:u:usp47|USP47]]|0.433|
|[[:human genes:p:polr2j|POLR2J]]|0.433|
|[[:human genes:s:scgb1c1|SCGB1C1]]|0.432|
|[[:human genes:c:chaf1a|CHAF1A]]|0.431|
|[[:human genes:t:twistnb|TWISTNB]]|0.43|
|[[:human genes:r:rps5|RPS5]]|0.429|
|[[:human genes:p:plekha4|PLEKHA4]]|0.429|
|[[:human genes:c:cbwd3|CBWD3]]|0.429|
|[[:human genes:m:myb|MYB]]|0.429|
|[[:human genes:b:b4galnt4|B4GALNT4]]|0.429|
|[[:human genes:n:nol9|NOL9]]|0.428|
|[[:human genes:f:fancd2|FANCD2]]|0.428|
|[[:human genes:a:atp6v1b2|ATP6V1B2]]|0.428|
|[[:human genes:d:ddx18|DDX18]]|0.427|
|[[:human genes:z:zbtb17|ZBTB17]]|0.426|
|[[:human genes:r:rpl32|RPL32]]|0.426|
|[[:human genes:r:rbm19|RBM19]]|0.425|
|[[:human genes:x:xrn2|XRN2]]|0.425|
|[[:human genes:p:polr2d|POLR2D]]|0.425|
|[[:human genes:a:abhd8|ABHD8]]|0.425|
|[[:human genes:c:cbwd6|CBWD6]]|0.424|
|[[:human genes:n:nup133|NUP133]]|0.423|
|[[:human genes:f:fcn2|FCN2]]|0.423|
|[[:human genes:e:eif4b|EIF4B]]|0.423|
|[[:human genes:f:ftsj3|FTSJ3]]|0.423|
|[[:human genes:p:psmd3|PSMD3]]|0.422|
|[[:human genes:e:eif4a3|EIF4A3]]|0.422|
|[[:human genes:n:nob1|NOB1]]|0.421|
|[[:human genes:c:cxxc1|CXXC1]]|0.421|
|[[:human genes:c:cnot3|CNOT3]]|0.42|
|[[:human genes:r:rps19bp1|RPS19BP1]]|0.419|
|[[:human genes:c:chd4|CHD4]]|0.419|
|[[:human genes:p:pno1|PNO1]]|0.419|
|[[:human genes:d:dtl|DTL]]|0.418|
|[[:human genes:n:nup93|NUP93]]|0.417|
|[[:human genes:n:npipa7|NPIPA7]]|0.417|
|[[:human genes:p:prpf19|PRPF19]]|0.417|
|[[:human genes:p:ppm1d|PPM1D]]|0.417|
|[[:human genes:n:npipa8|NPIPA8]]|0.417|
|[[:human genes:r:rpl27a|RPL27A]]|0.416|
|[[:human genes:t:tp53tg3b|TP53TG3B]]|0.416|
|[[:human genes:c:c1qtnf9b|C1QTNF9B]]|0.416|
|[[:human genes:t:tmem199|TMEM199]]|0.416|
|[[:human genes:e:egr2|EGR2]]|0.415|
|[[:human genes:e:exosc10|EXOSC10]]|0.415|
|[[:human genes:o:obscn|OBSCN]]|0.415|
|[[:human genes:t:tbc1d3f|TBC1D3F]]|0.414|
|[[:human genes:t:tp53tg3|TP53TG3]]|0.414|
|[[:human genes:t:tp53tg3c|TP53TG3C]]|0.414|
|[[:human genes:t:tmem160|TMEM160]]|0.413|
|[[:human genes:r:rps3a|RPS3A]]|0.413|
|[[:human genes:r:rfc1|RFC1]]|0.413|
|[[:human genes:r:rpl34|RPL34]]|0.412|
|[[:human genes:s:sf3a1|SF3A1]]|0.412|
|[[:human genes:l:leng8|LENG8]]|0.411|
|[[:human genes:s:sfswap|SFSWAP]]|0.411|
|[[:human genes:a:adck4|ADCK4]]|0.411|
|[[:human genes:e:eif3a|EIF3A]]|0.411|
|[[:human genes:c:cactin|CACTIN]]|0.41|
|[[:human genes:z:znf622|ZNF622]]|0.409|
|[[:human genes:a:ankle2|ANKLE2]]|0.409|
|[[:human genes:n:nlk|NLK]]|0.409|
|[[:human genes:c:cgb1|CGB1]]|0.409|
|[[:human genes:s:sema6b|SEMA6B]]|0.408|
|[[:human genes:g:gtpbp4|GTPBP4]]|0.408|
|[[:human genes:p:pzp|PZP]]|0.408|
|[[:human genes:r:rpl37|RPL37]]|0.408|
|[[:human genes:a:atp6v1e1|ATP6V1E1]]|0.408|
|[[:human genes:c:cyp11b2|CYP11B2]]|0.407|
|[[:human genes:s:sart1|SART1]]|0.407|
|[[:human genes:d:diexf|DIEXF]]|0.406|
|[[:human genes:l:lmo4|LMO4]]|0.406|
|[[:human genes:r:rpl27|RPL27]]|0.406|
|[[:human genes:m:muc5b|MUC5B]]|0.405|
|[[:human genes:r:rps4x|RPS4X]]|0.405|
|[[:human genes:r:rbm48|RBM48]]|0.405|
|[[:human genes:n:nppc|NPPC]]|0.405|
|[[:human genes:r:rpa2|RPA2]]|0.405|
|[[:human genes:p:psmc5|PSMC5]]|0.404|
|[[:human genes:r:rps3|RPS3]]|0.404|
|[[:human genes:e:espn|ESPN]]|0.404|
|[[:human genes:p:plk1|PLK1]]|0.404|
|[[:human genes:s:slc38a7|SLC38A7]]|0.403|
|[[:human genes:c:clcn6|CLCN6]]|0.403|
|[[:human genes:u:uba1|UBA1]]|0.403|
|[[:human genes:g:gltscr2|GLTSCR2]]|0.402|
|[[:human genes:p:psmb2|PSMB2]]|0.402|
|[[:human genes:e:exosc2|EXOSC2]]|0.401|
|[[:human genes:s:strn|STRN]]|0.401|
|[[:human genes:p:ppp1r10|PPP1R10]]|0.4|
|[[:human genes:c:copb2|COPB2]]|0.4|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 7/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|0/1|
|909776.0|0/1|
|bile duct|1/28|
|blood|1/28|
|bone|0/26|
|breast|0/33|
|central nervous system|0/56|
|cervix|0/4|
|colorectal|2/17|
|esophagus|0/13|
|fibroblast|0/1|
|gastric|0/16|
|kidney|0/21|
|liver|0/20|
|lung|0/75|
|lymphocyte|0/16|
|ovary|0/26|
|pancreas|0/24|
|peripheral nervous system|1/16|
|plasma cell|0/15|
|prostate|0/1|
|skin|0/24|
|soft tissue|0/9|
|thyroid|0/2|
|upper aerodigestive|0/22|
|urinary tract|0/29|
|uterus|1/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 62
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 1.11 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='GOLGA6L1 Expression in NALM6 Cells: 1.11'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>