======= PCDHB5 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: N/A
  * **<color #00a2e8>Official Name</color>**: N/A
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: N/A
  * **<color #00a2e8>UniProt</color>**: N/A
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=PCDHB5&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20PCDHB5|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: N/A

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='primary' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
|Cadherin|
|Cadherin 2|
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules|
|synapse assembly|
|homophilic cell adhesion via plasma membrane adhesion molecules|
|cell-cell adhesion via plasma-membrane adhesion molecules|
|synapse organization|
|chemical synaptic transmission|
|anterograde trans-synaptic signaling|
|trans-synaptic signaling|
|synaptic signaling|
|cell-cell adhesion|
|calcium ion binding|
|cell adhesion|
|biological adhesion|
|cell-cell signaling|
|integral component of plasma membrane|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='default' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp59|UMK57 1μM R01 exp59]]|-2.15|
|[[:results:exp46|HMS-I1 1μM R01 exp46]]|-2.03|
|[[:results:exp190|Vincristine 0.0005μM R04 exp190]]|-1.99|
|[[:results:exp48|Mubritinib 0.2μM R01 exp48]]|-1.95|
|[[:results:exp463|Caffeine 2600μM R08 exp463]]|-1.9|
|[[:results:exp214|2-Deoxy-D-glucose 800μM R05 exp214]]|-1.82|
|[[:results:exp456|Benzoate 20000μM R08 exp456]]|1.79|
|[[:results:exp187|proTAME 5μM R04 exp187]]|2|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
No correlation found to any other genes in chemogenomics.
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: N/A
^Tissue^Fraction Of Cell Lines Where Essential^
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 15668
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: -2.28 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='PCDHB5 Expression in NALM6 Cells: -2.28'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>