======= PRIM1 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: PRIM1
  * **<color #00a2e8>Official Name</color>**: DNA primase subunit 1
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=5557|5557]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/P49642|P49642]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=PRIM1&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20PRIM1|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: [[https://omim.org/entry/176635|Open OMIM]]

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**:  DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.

<button type='primary' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
|DNA primase S|
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|DNA primase activity|
|alpha DNA polymerase:primase complex|
|DNA replication, synthesis of RNA primer|
|telomere maintenance via semi-conservative replication|
|DNA replication initiation|
|nuclear DNA replication|
|cell cycle DNA replication|
|telomere maintenance|
|telomere organization|
|single-stranded DNA binding|
|G1/S transition of mitotic cell cycle|
|cell cycle G1/S phase transition|
|DNA-dependent DNA replication|
|DNA replication|
|mitotic cell cycle phase transition|
|cell cycle phase transition|
|anatomical structure homeostasis|
|mitotic cell cycle process|
|RNA biosynthetic process|
|mitotic cell cycle|
|DNA metabolic process|
|cellular homeostasis|
|cell cycle process|
|chromosome organization|
|nucleobase-containing compound biosynthetic process|
|heterocycle biosynthetic process|
|aromatic compound biosynthetic process|
|organic cyclic compound biosynthetic process|
|cell cycle|
|cellular nitrogen compound biosynthetic process|
|homeostatic process|
|RNA metabolic process|
|cellular macromolecule biosynthetic process|
|macromolecule biosynthetic process|
|membrane|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp22|MLN-4924 2μM R00 exp22]]|-2.56|
|[[:results:exp17|DABN 20μM R00 exp17]]|-2.51|
|[[:results:exp28|Pimelic-diphenylamide-106 5μM R00 exp28]]|-2.01|
|[[:results:exp24|Nocodazole 0.2μM R00 exp24]]|-1.75|
|[[:results:exp16|DABN 2μM R00 exp16]]|1.71|
|[[:results:exp71|KU-0063794 3.8μM R02 exp71]]|1.73|
|[[:results:exp70|INK128 0.2μM R02 exp70]]|1.79|
|[[:results:exp69|Deguelin 0.05μM R02 exp69]]|2.35|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:a:atp6v0b|ATP6V0B]]|0.648|
|[[:human genes:f:fbl|FBL]]|0.62|
|[[:human genes:w:wdr75|WDR75]]|0.616|
|[[:human genes:n:nxpe3|NXPE3]]|0.605|
|[[:human genes:z:znf783|ZNF783]]|0.602|
|[[:human genes:t:trim50|TRIM50]]|0.601|
|[[:human genes:e:ep300|EP300]]|0.596|
|[[:human genes:k:kiaa1211|KIAA1211]]|0.593|
|[[:human genes:d:dido1|DIDO1]]|0.592|
|[[:human genes:c:copb1|COPB1]]|0.589|
|[[:human genes:u:upf1|UPF1]]|0.588|
|[[:human genes:a:atp6v0a2|ATP6V0A2]]|0.583|
|[[:human genes:t:ticrr|TICRR]]|0.579|
|[[:human genes:n:naaladl2|NAALADL2]]|0.578|
|[[:human genes:p:psmb2|PSMB2]]|0.577|
|[[:human genes:a:aatf|AATF]]|0.575|
|[[:human genes:x:xab2|XAB2]]|0.575|
|[[:human genes:g:gcom1|GCOM1]]|0.573|
|[[:human genes:m:myzap|MYZAP]]|0.573|
|[[:human genes:t:tyms|TYMS]]|0.571|
|[[:human genes:s:supt16h|SUPT16H]]|0.569|
|[[:human genes:s:sf3a2|SF3A2]]|0.569|
|[[:human genes:s:socs1|SOCS1]]|0.567|
|[[:human genes:c:cma1|CMA1]]|0.565|
|[[:human genes:n:nup153|NUP153]]|0.564|
|[[:human genes:t:trappc8|TRAPPC8]]|0.563|
|[[:human genes:g:golga6l1|GOLGA6L1]]|0.562|
|[[:human genes:a:atp6v1a|ATP6V1A]]|0.559|
|[[:human genes:s:sppl3|SPPL3]]|0.559|
|[[:human genes:a:atp6v1c2|ATP6V1C2]]|0.556|
|[[:human genes:a:atp6v1b2|ATP6V1B2]]|0.555|
|[[:human genes:e:exosc6|EXOSC6]]|0.554|
|[[:human genes:c:ccdc108|CCDC108]]|0.553|
|[[:human genes:c:col2a1|COL2A1]]|0.551|
|[[:human genes:c:ctage4|CTAGE4]]|0.551|
|[[:human genes:t:tmem161a|TMEM161A]]|0.55|
|[[:human genes:m:mfsd3|MFSD3]]|0.55|
|[[:human genes:t:twistnb|TWISTNB]]|0.547|
|[[:human genes:d:dapk3|DAPK3]]|0.546|
|[[:human genes:a:aqr|AQR]]|0.545|
|[[:human genes:p:psmb4|PSMB4]]|0.543|
|[[:human genes:p:pole|POLE]]|0.54|
|[[:human genes:a:atp6v1c1|ATP6V1C1]]|0.54|
|[[:human genes:p:pigs|PIGS]]|0.539|
|[[:human genes:s:slc2a11|SLC2A11]]|0.539|
|[[:human genes:g:gid4|GID4]]|0.538|
|[[:human genes:n:nup160|NUP160]]|0.537|
|[[:human genes:m:mief1|MIEF1]]|0.537|
|[[:human genes:s:socs2|SOCS2]]|0.536|
|[[:human genes:z:znf805|ZNF805]]|0.536|
|[[:human genes:c:col25a1|COL25A1]]|0.534|
|[[:human genes:s:slc4a1|SLC4A1]]|0.531|
|[[:human genes:m:med17|MED17]]|0.531|
|[[:human genes:o:osbp|OSBP]]|0.53|
|[[:human genes:m:mettl1|METTL1]]|0.53|
|[[:human genes:b:bud31|BUD31]]|0.529|
|[[:human genes:s:scfd2|SCFD2]]|0.528|
|[[:human genes:u:utp6|UTP6]]|0.528|
|[[:human genes:t:tcp11x2|TCP11X2]]|0.528|
|[[:human genes:t:tspy1|TSPY1]]|0.524|
|[[:human genes:d:ddx3x|DDX3X]]|0.524|
|[[:human genes:n:nppc|NPPC]]|0.519|
|[[:human genes:e:epb41|EPB41]]|0.519|
|[[:human genes:m:map1lc3b|MAP1LC3B]]|0.518|
|[[:human genes:k:kri1|KRI1]]|0.518|
|[[:human genes:n:npipb5|NPIPB5]]|0.516|
|[[:human genes:p:ptgdr|PTGDR]]|0.516|
|[[:human genes:r:rad21|RAD21]]|0.516|
|[[:human genes:n:nbpf10|NBPF10]]|0.515|
|[[:human genes:c:cog1|COG1]]|0.514|
|[[:human genes:e:eif4a3|EIF4A3]]|0.514|
|[[:human genes:s:spata31a7|SPATA31A7]]|0.513|
|[[:human genes:s:s1pr4|S1PR4]]|0.513|
|[[:human genes:a:ankmy1|ANKMY1]]|0.513|
|[[:human genes:g:gp6|GP6]]|0.513|
|[[:human genes:k:kiaa1244|KIAA1244]]|0.513|
|[[:human genes:u:ubr7|UBR7]]|0.512|
|[[:human genes:g:gar1|GAR1]]|0.509|
|[[:human genes:a:agps|AGPS]]|0.508|
|[[:human genes:s:s100a9|S100A9]]|0.506|
|[[:human genes:r:ruvbl1|RUVBL1]]|0.505|
|[[:human genes:r:rpa1|RPA1]]|0.503|
|[[:human genes:p:ppfia3|PPFIA3]]|0.503|
|[[:human genes:s:scml1|SCML1]]|0.503|
|[[:human genes:c:c14orf93|C14orf93]]|0.503|
|[[:human genes:p:palm3|PALM3]]|0.503|
|[[:human genes:n:nol10|NOL10]]|0.502|
|[[:human genes:s:slc25a36|SLC25A36]]|0.502|
|[[:human genes:i:isy1|ISY1]]|0.501|
|[[:human genes:t:taf1|TAF1]]|0.501|
|[[:human genes:r:rpl35|RPL35]]|0.501|
|[[:human genes:p:pdcd1|PDCD1]]|0.5|
|[[:human genes:b:bid|BID]]|0.5|
|[[:human genes:v:vps37d|VPS37D]]|0.5|
|[[:human genes:r:rasip1|RASIP1]]|0.499|
|[[:human genes:c:copb2|COPB2]]|0.498|
|[[:human genes:r:rpl19|RPL19]]|0.498|
|[[:human genes:n:nfatc4|NFATC4]]|0.497|
|[[:human genes:a:aadacl2|AADACL2]]|0.497|
|[[:human genes:r:rps11|RPS11]]|0.495|
|[[:human genes:c:c1orf68|C1orf68]]|0.494|
|[[:human genes:t:tbl3|TBL3]]|0.494|
|[[:human genes:u:ubap2l|UBAP2L]]|0.494|
|[[:human genes:n:ndufaf3|NDUFAF3]]|0.494|
|[[:human genes:r:rps3a|RPS3A]]|0.493|
|[[:human genes:m:muc2|MUC2]]|0.493|
|[[:human genes:m:mstn|MSTN]]|0.492|
|[[:human genes:c:chd4|CHD4]]|0.491|
|[[:human genes:z:znf655|ZNF655]]|0.491|
|[[:human genes:z:znf574|ZNF574]]|0.49|
|[[:human genes:p:pola2|POLA2]]|0.49|
|[[:human genes:b:barx1|BARX1]]|0.489|
|[[:human genes:s:slc25a51|SLC25A51]]|0.489|
|[[:human genes:s:sf3b2|SF3B2]]|0.489|
|[[:human genes:c:cdc40|CDC40]]|0.489|
|[[:human genes:s:smad2|SMAD2]]|0.489|
|[[:human genes:n:nob1|NOB1]]|0.489|
|[[:human genes:s:s100a4|S100A4]]|0.487|
|[[:human genes:p:potee|POTEE]]|0.487|
|[[:human genes:d:dnajc11|DNAJC11]]|0.486|
|[[:human genes:a:atp6v0c|ATP6V0C]]|0.486|
|[[:human genes:e:exosc1|EXOSC1]]|0.485|
|[[:human genes:n:nfkbid|NFKBID]]|0.484|
|[[:human genes:g:golga8o|GOLGA8O]]|0.48|
|[[:human genes:i:ints5|INTS5]]|0.48|
|[[:human genes:p:ppp1r8|PPP1R8]]|0.48|
|[[:human genes:s:stxbp2|STXBP2]]|0.48|
|[[:human genes:t:tpx2|TPX2]]|0.48|
|[[:human genes:z:zc2hc1c|ZC2HC1C]]|0.479|
|[[:human genes:i:itgam|ITGAM]]|0.479|
|[[:human genes:c:colgalt1|COLGALT1]]|0.479|
|[[:human genes:t:topbp1|TOPBP1]]|0.478|
|[[:human genes:e:ermp1|ERMP1]]|0.478|
|[[:human genes:c:copz1|COPZ1]]|0.478|
|[[:human genes:r:rps8|RPS8]]|0.478|
|[[:human genes:p:pmaip1|PMAIP1]]|0.477|
|[[:human genes:t:tbc1d17|TBC1D17]]|0.477|
|[[:human genes:t:tspy2|TSPY2]]|0.476|
|[[:human genes:d:donson|DONSON]]|0.476|
|[[:human genes:t:tuba8|TUBA8]]|0.476|
|[[:human genes:y:yy1|YY1]]|0.475|
|[[:human genes:m:madcam1|MADCAM1]]|0.474|
|[[:human genes:c:cog8|COG8]]|0.473|
|[[:human genes:p:pip4k2b|PIP4K2B]]|0.472|
|[[:human genes:p:polr2j|POLR2J]]|0.47|
|[[:human genes:c:copg1|COPG1]]|0.47|
|[[:human genes:m:mgrn1|MGRN1]]|0.47|
|[[:human genes:n:nelfcd|NELFCD]]|0.47|
|[[:human genes:f:fam194b|FAM194B]]|0.47|
|[[:human genes:r:rnf113a|RNF113A]]|0.47|
|[[:human genes:m:mdm2|MDM2]]|0.469|
|[[:human genes:s:sf3a3|SF3A3]]|0.468|
|[[:human genes:m:mcrs1|MCRS1]]|0.468|
|[[:human genes:h:hist1h2bf|HIST1H2BF]]|0.468|
|[[:human genes:c:chaf1a|CHAF1A]]|0.468|
|[[:human genes:k:krt36|KRT36]]|0.468|
|[[:human genes:d:ddx47|DDX47]]|0.468|
|[[:human genes:p:pcna|PCNA]]|0.466|
|[[:human genes:k:krt78|KRT78]]|0.466|
|[[:human genes:s:supt5h|SUPT5H]]|0.466|
|[[:human genes:c:cox7a2l|COX7A2L]]|0.465|
|[[:human genes:o:or4b1|OR4B1]]|0.465|
|[[:human genes:p:prkacb|PRKACB]]|0.464|
|[[:human genes:n:ndufs8|NDUFS8]]|0.464|
|[[:human genes:s:smpd4|SMPD4]]|0.463|
|[[:human genes:d:dnttip2|DNTTIP2]]|0.463|
|[[:human genes:p:pde9a|PDE9A]]|0.462|
|[[:human genes:z:znf254|ZNF254]]|0.462|
|[[:human genes:s:strn|STRN]]|0.461|
|[[:human genes:s:stx6|STX6]]|0.46|
|[[:human genes:c:cdk6|CDK6]]|0.46|
|[[:human genes:t:tceb3c|TCEB3C]]|0.46|
|[[:human genes:a:abcc10|ABCC10]]|0.459|
|[[:human genes:r:rilpl2|RILPL2]]|0.459|
|[[:human genes:r:rpl27|RPL27]]|0.458|
|[[:human genes:e:exosc5|EXOSC5]]|0.457|
|[[:human genes:g:gprc5b|GPRC5B]]|0.457|
|[[:human genes:p:pepd|PEPD]]|0.457|
|[[:human genes:m:myb|MYB]]|0.457|
|[[:human genes:r:robo4|ROBO4]]|0.456|
|[[:human genes:r:rilpl1|RILPL1]]|0.456|
|[[:human genes:l:lman1|LMAN1]]|0.456|
|[[:human genes:p:pi4kb|PI4KB]]|0.456|
|[[:human genes:p:polr2j3|POLR2J3]]|0.456|
|[[:human genes:a:atp2b4|ATP2B4]]|0.455|
|[[:human genes:p:pank2|PANK2]]|0.455|
|[[:human genes:c:ca8|CA8]]|0.454|
|[[:human genes:s:stard7|STARD7]]|0.454|
|[[:human genes:t:tcf20|TCF20]]|0.454|
|[[:human genes:m:mt1e|MT1E]]|0.453|
|[[:human genes:r:rpl13a|RPL13A]]|0.453|
|[[:human genes:r:rpl23|RPL23]]|0.453|
|[[:human genes:c:ccnd3|CCND3]]|0.453|
|[[:human genes:t:trdn|TRDN]]|0.452|
|[[:human genes:t:tbc1d3h|TBC1D3H]]|0.452|
|[[:human genes:r:riok2|RIOK2]]|0.452|
|[[:human genes:u:utp20|UTP20]]|0.452|
|[[:human genes:r:rpl15|RPL15]]|0.452|
|[[:human genes:i:ing2|ING2]]|0.452|
|[[:human genes:i:ifitm1|IFITM1]]|0.451|
|[[:human genes:r:rps9|RPS9]]|0.451|
|[[:human genes:e:enpp3|ENPP3]]|0.451|
|[[:human genes:p:pan3|PAN3]]|0.45|
|[[:human genes:s:syf2|SYF2]]|0.45|
|[[:human genes:t:tbc1d3f|TBC1D3F]]|0.45|
|[[:human genes:s:snrpa1|SNRPA1]]|0.449|
|[[:human genes:r:ranbp2|RANBP2]]|0.449|
|[[:human genes:a:als2cl|ALS2CL]]|0.449|
|[[:human genes:p:polr2c|POLR2C]]|0.448|
|[[:human genes:g:gna15|GNA15]]|0.447|
|[[:human genes:n:ndufv2|NDUFV2]]|0.447|
|[[:human genes:p:pkib|PKIB]]|0.447|
|[[:human genes:s:srm|SRM]]|0.446|
|[[:human genes:d:dhx8|DHX8]]|0.446|
|[[:human genes:e:eras|ERAS]]|0.446|
|[[:human genes:w:wdr74|WDR74]]|0.446|
|[[:human genes:c:ctage9|CTAGE9]]|0.446|
|[[:human genes:a:armc9|ARMC9]]|0.446|
|[[:human genes:c:c12orf68|C12orf68]]|0.446|
|[[:human genes:r:rps19|RPS19]]|0.446|
|[[:human genes:s:sult2b1|SULT2B1]]|0.445|
|[[:human genes:a:arcn1|ARCN1]]|0.445|
|[[:human genes:h:hexim1|HEXIM1]]|0.445|
|[[:human genes:n:nhlrc3|NHLRC3]]|0.445|
|[[:human genes:c:cog4|COG4]]|0.445|
|[[:human genes:a:actl9|ACTL9]]|0.445|
|[[:human genes:r:rcl1|RCL1]]|0.445|
|[[:human genes:t:thada|THADA]]|0.445|
|[[:human genes:p:ppm1f|PPM1F]]|0.444|
|[[:human genes:k:kir2dl1|KIR2DL1]]|0.444|
|[[:human genes:a:atp6v1e1|ATP6V1E1]]|0.444|
|[[:human genes:g:gpt|GPT]]|0.443|
|[[:human genes:o:or5w2|OR5W2]]|0.443|
|[[:human genes:d:dpep3|DPEP3]]|0.443|
|[[:human genes:c:ckap5|CKAP5]]|0.442|
|[[:human genes:s:slco4c1|SLCO4C1]]|0.442|
|[[:human genes:t:tmcc2|TMCC2]]|0.442|
|[[:human genes:a:aldh1b1|ALDH1B1]]|0.442|
|[[:human genes:s:scaf1|SCAF1]]|0.441|
|[[:human genes:e:exd1|EXD1]]|0.441|
|[[:human genes:a:atp6v1d|ATP6V1D]]|0.441|
|[[:human genes:i:ints6|INTS6]]|0.441|
|[[:human genes:f:fbxo5|FBXO5]]|0.441|
|[[:human genes:k:kansl1|KANSL1]]|0.44|
|[[:human genes:s:srsf8|SRSF8]]|0.44|
|[[:human genes:c:chrna2|CHRNA2]]|0.44|
|[[:human genes:p:pds5a|PDS5A]]|0.44|
|[[:human genes:z:zcchc9|ZCCHC9]]|0.44|
|[[:human genes:z:znf541|ZNF541]]|0.439|
|[[:human genes:r:rpl12|RPL12]]|0.439|
|[[:human genes:e:emc7|EMC7]]|0.439|
|[[:human genes:n:nln|NLN]]|0.439|
|[[:human genes:s:slc9a1|SLC9A1]]|0.439|
|[[:human genes:a:aurkaip1|AURKAIP1]]|0.438|
|[[:human genes:n:nubpl|NUBPL]]|0.438|
|[[:human genes:m:mphosph10|MPHOSPH10]]|0.438|
|[[:human genes:r:rrp36|RRP36]]|0.438|
|[[:human genes:k:kmo|KMO]]|0.438|
|[[:human genes:m:med14|MED14]]|0.437|
|[[:human genes:e:eps15l1|EPS15L1]]|0.437|
|[[:human genes:c:cacna2d4|CACNA2D4]]|0.437|
|[[:human genes:s:sdad1|SDAD1]]|0.437|
|[[:human genes:c:cnih1|CNIH1]]|0.437|
|[[:human genes:l:lad1|LAD1]]|0.436|
|[[:human genes:t:tsnaxip1|TSNAXIP1]]|0.436|
|[[:human genes:b:bcas2|BCAS2]]|0.435|
|[[:human genes:k:kcnj12|KCNJ12]]|0.435|
|[[:human genes:p:pcca|PCCA]]|0.435|
|[[:human genes:h:heatr1|HEATR1]]|0.435|
|[[:human genes:t:tbkbp1|TBKBP1]]|0.435|
|[[:human genes:k:kiaa0947|KIAA0947]]|0.434|
|[[:human genes:i:iglon5|IGLON5]]|0.433|
|[[:human genes:t:tceb3cl|TCEB3CL]]|0.433|
|[[:human genes:k:krt82|KRT82]]|0.433|
|[[:human genes:s:sf3b3|SF3B3]]|0.433|
|[[:human genes:z:znf454|ZNF454]]|0.432|
|[[:human genes:c:cog3|COG3]]|0.432|
|[[:human genes:s:smg1|SMG1]]|0.432|
|[[:human genes:p:poc1a|POC1A]]|0.432|
|[[:human genes:r:rrp7a|RRP7A]]|0.431|
|[[:human genes:c:cln8|CLN8]]|0.431|
|[[:human genes:c:copa|COPA]]|0.431|
|[[:human genes:t:timeless|TIMELESS]]|0.431|
|[[:human genes:r:rmdn3|RMDN3]]|0.431|
|[[:human genes:a:abi3bp|ABI3BP]]|0.431|
|[[:human genes:p:ptma|PTMA]]|0.43|
|[[:human genes:c:ccdc64|CCDC64]]|0.43|
|[[:human genes:s:smco3|SMCO3]]|0.43|
|[[:human genes:c:cdh13|CDH13]]|0.43|
|[[:human genes:m:mdh2|MDH2]]|0.43|
|[[:human genes:s:srgap1|SRGAP1]]|0.429|
|[[:human genes:p:psma6|PSMA6]]|0.429|
|[[:human genes:m:mettl24|METTL24]]|0.429|
|[[:human genes:p:pif1|PIF1]]|0.429|
|[[:human genes:s:snip1|SNIP1]]|0.429|
|[[:human genes:s:supt6h|SUPT6H]]|0.429|
|[[:human genes:g:golga6l3|GOLGA6L3]]|0.428|
|[[:human genes:c:cd6|CD6]]|0.428|
|[[:human genes:n:nup214|NUP214]]|0.428|
|[[:human genes:c:ccdc86|CCDC86]]|0.427|
|[[:human genes:z:znf442|ZNF442]]|0.427|
|[[:human genes:d:dnajc17|DNAJC17]]|0.426|
|[[:human genes:s:sh3bp1|SH3BP1]]|0.426|
|[[:human genes:n:nsun4|NSUN4]]|0.425|
|[[:human genes:s:sf3b5|SF3B5]]|0.425|
|[[:human genes:m:mdc1|MDC1]]|0.425|
|[[:human genes:b:bcas3|BCAS3]]|0.425|
|[[:human genes:n:nelfa|NELFA]]|0.425|
|[[:human genes:m:mcat|MCAT]]|0.425|
|[[:human genes:s:snx11|SNX11]]|0.425|
|[[:human genes:d:dcps|DCPS]]|0.424|
|[[:human genes:a:arhgef37|ARHGEF37]]|0.424|
|[[:human genes:b:b3galt5|B3GALT5]]|0.423|
|[[:human genes:v:vps52|VPS52]]|0.423|
|[[:human genes:p:pbxip1|PBXIP1]]|0.423|
|[[:human genes:a:abhd17a|ABHD17A]]|0.423|
|[[:human genes:s:ston2|STON2]]|0.423|
|[[:human genes:p:pwp2|PWP2]]|0.422|
|[[:human genes:r:rps2|RPS2]]|0.422|
|[[:human genes:r:rbms1|RBMS1]]|0.422|
|[[:human genes:a:acad9|ACAD9]]|0.422|
|[[:human genes:c:chek1|CHEK1]]|0.422|
|[[:human genes:b:brms1|BRMS1]]|0.422|
|[[:human genes:t:tbc1d4|TBC1D4]]|0.422|
|[[:human genes:n:nup93|NUP93]]|0.421|
|[[:human genes:f:fam111a|FAM111A]]|0.421|
|[[:human genes:z:zbtb7a|ZBTB7A]]|0.421|
|[[:human genes:l:lefty1|LEFTY1]]|0.421|
|[[:human genes:s:sec22c|SEC22C]]|0.42|
|[[:human genes:z:znf687|ZNF687]]|0.42|
|[[:human genes:a:aamp|AAMP]]|0.419|
|[[:human genes:n:nfya|NFYA]]|0.419|
|[[:human genes:a:adamts18|ADAMTS18]]|0.419|
|[[:human genes:r:rpa2|RPA2]]|0.419|
|[[:human genes:a:atp6ap1|ATP6AP1]]|0.419|
|[[:human genes:r:rap1gap2|RAP1GAP2]]|0.419|
|[[:human genes:n:nr2c2ap|NR2C2AP]]|0.418|
|[[:human genes:p:phf2|PHF2]]|0.418|
|[[:human genes:r:rps12|RPS12]]|0.418|
|[[:human genes:l:lama2|LAMA2]]|0.418|
|[[:human genes:m:mtch2|MTCH2]]|0.418|
|[[:human genes:p:polr1a|POLR1A]]|0.418|
|[[:human genes:b:brca1|BRCA1]]|0.417|
|[[:human genes:g:golga2|GOLGA2]]|0.417|
|[[:human genes:g:glrx|GLRX]]|0.417|
|[[:human genes:f:fzd1|FZD1]]|0.417|
|[[:human genes:z:znf652|ZNF652]]|0.416|
|[[:human genes:d:dcp1b|DCP1B]]|0.416|
|[[:human genes:t:tfrc|TFRC]]|0.415|
|[[:human genes:z:zfat|ZFAT]]|0.415|
|[[:human genes:d:diexf|DIEXF]]|0.415|
|[[:human genes:c:clstn1|CLSTN1]]|0.415|
|[[:human genes:e:exosc7|EXOSC7]]|0.415|
|[[:human genes:w:wars2|WARS2]]|0.415|
|[[:human genes:v:vps28|VPS28]]|0.415|
|[[:human genes:a:ankrd7|ANKRD7]]|0.415|
|[[:human genes:t:traip|TRAIP]]|0.415|
|[[:human genes:l:ldhd|LDHD]]|0.414|
|[[:human genes:h:hnrnpcl1|HNRNPCL1]]|0.414|
|[[:human genes:d:dpy19l3|DPY19L3]]|0.414|
|[[:human genes:p:pcf11|PCF11]]|0.414|
|[[:human genes:g:gpx4|GPX4]]|0.414|
|[[:human genes:s:stau2|STAU2]]|0.413|
|[[:human genes:p:pcdhga2|PCDHGA2]]|0.413|
|[[:human genes:t:tbc1d3|TBC1D3]]|0.413|
|[[:human genes:m:mov10l1|MOV10L1]]|0.413|
|[[:human genes:m:map1lc3c|MAP1LC3C]]|0.412|
|[[:human genes:s:sart1|SART1]]|0.412|
|[[:human genes:x:xkr4|XKR4]]|0.412|
|[[:human genes:r:rpl10a|RPL10A]]|0.412|
|[[:human genes:h:hinfp|HINFP]]|0.412|
|[[:human genes:l:lrrc46|LRRC46]]|0.412|
|[[:human genes:f:fxyd1|FXYD1]]|0.411|
|[[:human genes:a:arl6ip1|ARL6IP1]]|0.411|
|[[:human genes:n:nol6|NOL6]]|0.411|
|[[:human genes:z:zkscan4|ZKSCAN4]]|0.411|
|[[:human genes:e:emc9|EMC9]]|0.411|
|[[:human genes:t:trim38|TRIM38]]|0.411|
|[[:human genes:s:sys1|SYS1]]|0.41|
|[[:human genes:a:akt1s1|AKT1S1]]|0.41|
|[[:human genes:g:golga8n|GOLGA8N]]|0.41|
|[[:human genes:a:agap5|AGAP5]]|0.41|
|[[:human genes:g:gnly|GNLY]]|0.41|
|[[:human genes:o:or9q2|OR9Q2]]|0.41|
|[[:human genes:r:rgs4|RGS4]]|0.41|
|[[:human genes:c:chdh|CHDH]]|0.409|
|[[:human genes:z:zmat4|ZMAT4]]|0.409|
|[[:human genes:h:hcfc1|HCFC1]]|0.409|
|[[:human genes:i:igfn1|IGFN1]]|0.409|
|[[:human genes:s:snrpb|SNRPB]]|0.409|
|[[:human genes:a:aqp5|AQP5]]|0.409|
|[[:human genes:t:timmdc1|TIMMDC1]]|0.409|
|[[:human genes:w:wdr7|WDR7]]|0.408|
|[[:human genes:d:ddx49|DDX49]]|0.408|
|[[:human genes:c:cyb561a3|CYB561A3]]|0.408|
|[[:human genes:k:kiaa0556|KIAA0556]]|0.407|
|[[:human genes:d:dnaaf2|DNAAF2]]|0.407|
|[[:human genes:r:rps7|RPS7]]|0.407|
|[[:human genes:e:emcn|EMCN]]|0.407|
|[[:human genes:p:polr2b|POLR2B]]|0.407|
|[[:human genes:n:nedd4|NEDD4]]|0.407|
|[[:human genes:c:cope|COPE]]|0.407|
|[[:human genes:v:vwa7|VWA7]]|0.407|
|[[:human genes:p:pola1|POLA1]]|0.407|
|[[:human genes:g:gnat1|GNAT1]]|0.406|
|[[:human genes:g:golt1a|GOLT1A]]|0.406|
|[[:human genes:p:pnma1|PNMA1]]|0.406|
|[[:human genes:g:ganc|GANC]]|0.406|
|[[:human genes:p:prap1|PRAP1]]|0.406|
|[[:human genes:v:vwa2|VWA2]]|0.405|
|[[:human genes:z:znf148|ZNF148]]|0.405|
|[[:human genes:d:dgke|DGKE]]|0.404|
|[[:human genes:t:tox3|TOX3]]|0.404|
|[[:human genes:m:myocd|MYOCD]]|0.404|
|[[:human genes:v:vps54|VPS54]]|0.404|
|[[:human genes:r:rhebl1|RHEBL1]]|0.403|
|[[:human genes:r:rbm22|RBM22]]|0.403|
|[[:human genes:s:soat2|SOAT2]]|0.403|
|[[:human genes:t:tfip11|TFIP11]]|0.403|
|[[:human genes:r:rpap1|RPAP1]]|0.403|
|[[:human genes:a:arhgef11|ARHGEF11]]|0.403|
|[[:human genes:n:nanos2|NANOS2]]|0.403|
|[[:human genes:g:gdf9|GDF9]]|0.403|
|[[:human genes:s:sox17|SOX17]]|0.402|
|[[:human genes:f:fgf23|FGF23]]|0.402|
|[[:human genes:s:sult1a3|SULT1A3]]|0.402|
|[[:human genes:n:nupl1|NUPL1]]|0.402|
|[[:human genes:d:dusp5|DUSP5]]|0.402|
|[[:human genes:b:brd4|BRD4]]|0.402|
|[[:human genes:n:nup62|NUP62]]|0.402|
|[[:human genes:r:rhbdd3|RHBDD3]]|0.402|
|[[:human genes:s:sult1a4|SULT1A4]]|0.402|
|[[:human genes:n:nudt1|NUDT1]]|0.402|
|[[:human genes:d:dkk1|DKK1]]|0.401|
|[[:human genes:d:dph5|DPH5]]|0.401|
|[[:human genes:n:npipa8|NPIPA8]]|0.401|
|[[:human genes:c:c3orf22|C3orf22]]|0.401|
|[[:human genes:o:odf3|ODF3]]|0.401|
|[[:human genes:f:fam114a1|FAM114A1]]|0.401|
|[[:human genes:s:slitrk5|SLITRK5]]|0.4|
|[[:human genes:a:atp6ap2|ATP6AP2]]|0.4|
|[[:human genes:n:npipa7|NPIPA7]]|0.4|
|[[:human genes:n:noc4l|NOC4L]]|0.4|
|[[:human genes:r:rps3|RPS3]]|0.4|
|[[:human genes:t:tceb3cl2|TCEB3CL2]]|0.4|
|[[:human genes:z:zzef1|ZZEF1]]|0.4|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 729/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|1/1|
|909776.0|1/1|
|bile duct|28/28|
|blood|28/28|
|bone|26/26|
|breast|31/33|
|central nervous system|56/56|
|cervix|4/4|
|colorectal|17/17|
|esophagus|13/13|
|fibroblast|1/1|
|gastric|16/16|
|kidney|19/21|
|liver|19/20|
|lung|74/75|
|lymphocyte|16/16|
|ovary|25/26|
|pancreas|24/24|
|peripheral nervous system|16/16|
|plasma cell|15/15|
|prostate|1/1|
|skin|23/24|
|soft tissue|9/9|
|thyroid|2/2|
|upper aerodigestive|22/22|
|urinary tract|29/29|
|uterus|5/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 160
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 5.56 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='PRIM1 Expression in NALM6 Cells: 5.56'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>