======= RPL35 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: RPL35
  * **<color #00a2e8>Official Name</color>**: ribosomal protein L35
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=11224|11224]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/P42766|P42766]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=RPL35&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20RPL35|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: [[https://omim.org/entry/618315|Open OMIM]]

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**:  Component of the large ribosomal subunit. {ECO:0000305|PubMed:12962325}.

<button type='primary' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
|Ribosomal L29|
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)|
|maturation of LSU-rRNA|
|cytosolic large ribosomal subunit|
|ribosomal large subunit biogenesis|
|SRP-dependent cotranslational protein targeting to membrane|
|cotranslational protein targeting to membrane|
|protein targeting to ER|
|establishment of protein localization to endoplasmic reticulum|
|viral transcription|
|nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|
|viral gene expression|
|protein localization to endoplasmic reticulum|
|translational initiation|
|protein targeting to membrane|
|mRNA binding|
|structural constituent of ribosome|
|nuclear-transcribed mRNA catabolic process|
|rRNA processing|
|mRNA catabolic process|
|rRNA metabolic process|
|RNA catabolic process|
|establishment of protein localization to membrane|
|ribosome biogenesis|
|protein targeting|
|nucleobase-containing compound catabolic process|
|translation|
|ncRNA processing|
|peptide biosynthetic process|
|establishment of protein localization to organelle|
|heterocycle catabolic process|
|cellular nitrogen compound catabolic process|
|aromatic compound catabolic process|
|ribonucleoprotein complex biogenesis|
|ncRNA metabolic process|
|organic cyclic compound catabolic process|
|protein localization to membrane|
|amide biosynthetic process|
|peptide metabolic process|
|mRNA metabolic process|
|viral process|
|protein localization to organelle|
|symbiotic process|
|cellular amide metabolic process|
|interspecies interaction between organisms|
|nucleolus|
|RNA processing|
|cellular macromolecule catabolic process|
|intracellular protein transport|
|macromolecule catabolic process|
|RNA binding|
|organonitrogen compound biosynthetic process|
|protein transport|
|intracellular transport|
|peptide transport|
|amide transport|
|cellular protein localization|
|cellular macromolecule localization|
|establishment of protein localization|
|cellular nitrogen compound biosynthetic process|
|RNA metabolic process|
|cellular macromolecule biosynthetic process|
|negative regulation of gene expression|
|macromolecule biosynthetic process|
|organic substance catabolic process|
|cellular catabolic process|
|establishment of localization in cell|
|nitrogen compound transport|
|membrane|
|gene expression|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp7|Bortezomib 0.05μM R00 exp7]]|-2.49|
|[[:results:exp34|Rotenone 20μM R00 exp34]]|-2.44|
|[[:results:exp20|Etoposide 10μM R00 exp20]]|-2.2|
|[[:results:exp341|BRD2 inhibitor II 20μM R07 exp341]]|1.73|
|[[:results:exp32|Rifampicin 10μM R00 exp32]]|1.73|
|[[:results:exp282|Fluvastatin 2.2μM R06 exp282]]|1.81|
|[[:results:exp292|Menadione 5μM R06 exp292]]|1.83|
|[[:results:exp122|Golgicide-A 4μM R03 exp122]]|1.88|
|[[:results:exp247|UM0130462 0.025 to 0.035μM day4 R05 exp247]]|1.93|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:p:psmb4|PSMB4]]|0.625|
|[[:human genes:p:polr2j3|POLR2J3]]|0.606|
|[[:human genes:t:tceb3c|TCEB3C]]|0.589|
|[[:human genes:s:supt5h|SUPT5H]]|0.574|
|[[:human genes:c:cactin|CACTIN]]|0.572|
|[[:human genes:e:exosc9|EXOSC9]]|0.564|
|[[:human genes:t:tceb3cl2|TCEB3CL2]]|0.559|
|[[:human genes:t:tceb3cl|TCEB3CL]]|0.554|
|[[:human genes:p:psmb2|PSMB2]]|0.552|
|[[:human genes:r:rad51|RAD51]]|0.549|
|[[:human genes:c:cox7a2l|COX7A2L]]|0.548|
|[[:human genes:v:vps28|VPS28]]|0.544|
|[[:human genes:r:rpl6|RPL6]]|0.537|
|[[:human genes:c:chd4|CHD4]]|0.537|
|[[:human genes:p:psma6|PSMA6]]|0.535|
|[[:human genes:r:rrp7a|RRP7A]]|0.534|
|[[:human genes:t:tbc1d3c|TBC1D3C]]|0.532|
|[[:human genes:c:c14orf93|C14orf93]]|0.532|
|[[:human genes:r:rps12|RPS12]]|0.528|
|[[:human genes:i:igfn1|IGFN1]]|0.528|
|[[:human genes:c:cbwd6|CBWD6]]|0.527|
|[[:human genes:e:ebna1bp2|EBNA1BP2]]|0.527|
|[[:human genes:t:tbc1d3h|TBC1D3H]]|0.527|
|[[:human genes:d:dtl|DTL]]|0.525|
|[[:human genes:n:narfl|NARFL]]|0.523|
|[[:human genes:r:rps7|RPS7]]|0.522|
|[[:human genes:u:utp20|UTP20]]|0.522|
|[[:human genes:p:psma7|PSMA7]]|0.522|
|[[:human genes:g:golga8j|GOLGA8J]]|0.52|
|[[:human genes:r:rps2|RPS2]]|0.52|
|[[:human genes:d:ddx56|DDX56]]|0.52|
|[[:human genes:r:rps9|RPS9]]|0.52|
|[[:human genes:p:psmd2|PSMD2]]|0.52|
|[[:human genes:k:kiaa0947|KIAA0947]]|0.518|
|[[:human genes:t:tbc1d3g|TBC1D3G]]|0.517|
|[[:human genes:n:nol10|NOL10]]|0.517|
|[[:human genes:m:mdm2|MDM2]]|0.515|
|[[:human genes:o:orc1|ORC1]]|0.515|
|[[:human genes:d:dnttip2|DNTTIP2]]|0.514|
|[[:human genes:s:sart1|SART1]]|0.514|
|[[:human genes:i:ik|IK]]|0.513|
|[[:human genes:p:pan3|PAN3]]|0.512|
|[[:human genes:w:wdr75|WDR75]]|0.511|
|[[:human genes:t:tbc1d3f|TBC1D3F]]|0.511|
|[[:human genes:r:rps5|RPS5]]|0.51|
|[[:human genes:t:tspy2|TSPY2]]|0.51|
|[[:human genes:c:c1qtnf9b|C1QTNF9B]]|0.509|
|[[:human genes:s:supt6h|SUPT6H]]|0.508|
|[[:human genes:r:rpl34|RPL34]]|0.507|
|[[:human genes:p:pola1|POLA1]]|0.506|
|[[:human genes:p:psmc1|PSMC1]]|0.505|
|[[:human genes:s:sf3a1|SF3A1]]|0.504|
|[[:human genes:b:bysl|BYSL]]|0.504|
|[[:human genes:c:cbwd3|CBWD3]]|0.503|
|[[:human genes:l:lad1|LAD1]]|0.503|
|[[:human genes:d:ddtl|DDTL]]|0.502|
|[[:human genes:p:pole|POLE]]|0.502|
|[[:human genes:p:pola2|POLA2]]|0.501|
|[[:human genes:p:prim1|PRIM1]]|0.501|
|[[:human genes:n:nup160|NUP160]]|0.5|
|[[:human genes:t:tbc1d3i|TBC1D3I]]|0.5|
|[[:human genes:t:tbc1d3k|TBC1D3K]]|0.5|
|[[:human genes:t:tbc1d3e|TBC1D3E]]|0.5|
|[[:human genes:t:tbc1d3l|TBC1D3L]]|0.5|
|[[:human genes:c:cbwd5|CBWD5]]|0.499|
|[[:human genes:s:slc4a1|SLC4A1]]|0.497|
|[[:human genes:a:atp6v1b2|ATP6V1B2]]|0.496|
|[[:human genes:e:exosc8|EXOSC8]]|0.495|
|[[:human genes:r:ranbp2|RANBP2]]|0.494|
|[[:human genes:t:tspy1|TSPY1]]|0.493|
|[[:human genes:l:lrr1|LRR1]]|0.49|
|[[:human genes:r:rps19bp1|RPS19BP1]]|0.49|
|[[:human genes:o:orc6|ORC6]]|0.489|
|[[:human genes:p:psmb1|PSMB1]]|0.489|
|[[:human genes:n:npipb5|NPIPB5]]|0.488|
|[[:human genes:c:col2a1|COL2A1]]|0.487|
|[[:human genes:p:pwp2|PWP2]]|0.486|
|[[:human genes:r:rrn3|RRN3]]|0.486|
|[[:human genes:s:sf3a3|SF3A3]]|0.485|
|[[:human genes:a:aqr|AQR]]|0.485|
|[[:human genes:z:znf574|ZNF574]]|0.485|
|[[:human genes:r:rps3a|RPS3A]]|0.485|
|[[:human genes:c:ccna2|CCNA2]]|0.485|
|[[:human genes:h:hap1|HAP1]]|0.484|
|[[:human genes:r:rpl38|RPL38]]|0.481|
|[[:human genes:v:vasn|VASN]]|0.481|
|[[:human genes:r:rbbp5|RBBP5]]|0.48|
|[[:human genes:r:rnf113a|RNF113A]]|0.479|
|[[:human genes:c:cope|COPE]]|0.479|
|[[:human genes:c:ccdc116|CCDC116]]|0.479|
|[[:human genes:c:copb1|COPB1]]|0.478|
|[[:human genes:s:snrpa1|SNRPA1]]|0.478|
|[[:human genes:p:psmc6|PSMC6]]|0.477|
|[[:human genes:z:znf655|ZNF655]]|0.476|
|[[:human genes:p:psmb3|PSMB3]]|0.476|
|[[:human genes:k:krt78|KRT78]]|0.475|
|[[:human genes:p:psmc5|PSMC5]]|0.474|
|[[:human genes:t:tbc1d3|TBC1D3]]|0.474|
|[[:human genes:m:mfsd12|MFSD12]]|0.474|
|[[:human genes:g:golga6l1|GOLGA6L1]]|0.474|
|[[:human genes:p:psmd3|PSMD3]]|0.473|
|[[:human genes:c:chaf1a|CHAF1A]]|0.473|
|[[:human genes:a:acsf2|ACSF2]]|0.472|
|[[:human genes:c:ctage4|CTAGE4]]|0.472|
|[[:human genes:c:copg1|COPG1]]|0.472|
|[[:human genes:p:psmd14|PSMD14]]|0.472|
|[[:human genes:r:rps11|RPS11]]|0.472|
|[[:human genes:z:zfand5|ZFAND5]]|0.472|
|[[:human genes:c:cdc6|CDC6]]|0.471|
|[[:human genes:h:hist2h3a|HIST2H3A]]|0.471|
|[[:human genes:s:slc6a17|SLC6A17]]|0.471|
|[[:human genes:h:hist2h3c|HIST2H3C]]|0.471|
|[[:human genes:o:or10g3|OR10G3]]|0.47|
|[[:human genes:n:npipb11|NPIPB11]]|0.469|
|[[:human genes:w:wdr43|WDR43]]|0.469|
|[[:human genes:c:cdt1|CDT1]]|0.468|
|[[:human genes:s:ssh2|SSH2]]|0.468|
|[[:human genes:n:nfatc4|NFATC4]]|0.467|
|[[:human genes:p:polr2d|POLR2D]]|0.467|
|[[:human genes:c:cdc73|CDC73]]|0.467|
|[[:human genes:p:psmd1|PSMD1]]|0.467|
|[[:human genes:t:tspy8|TSPY8]]|0.467|
|[[:human genes:a:aatf|AATF]]|0.466|
|[[:human genes:e:exosc1|EXOSC1]]|0.465|
|[[:human genes:c:cebpz|CEBPZ]]|0.465|
|[[:human genes:t:ticrr|TICRR]]|0.464|
|[[:human genes:t:tfip11|TFIP11]]|0.463|
|[[:human genes:g:golga6l6|GOLGA6L6]]|0.463|
|[[:human genes:a:apc2|APC2]]|0.462|
|[[:human genes:s:slc38a7|SLC38A7]]|0.46|
|[[:human genes:k:kpnb1|KPNB1]]|0.46|
|[[:human genes:s:smg7|SMG7]]|0.46|
|[[:human genes:a:atp6v1c1|ATP6V1C1]]|0.46|
|[[:human genes:k:kctd17|KCTD17]]|0.459|
|[[:human genes:a:art5|ART5]]|0.458|
|[[:human genes:e:exosc6|EXOSC6]]|0.458|
|[[:human genes:p:ppfia4|PPFIA4]]|0.458|
|[[:human genes:m:mphosph10|MPHOSPH10]]|0.457|
|[[:human genes:p:psmc2|PSMC2]]|0.457|
|[[:human genes:p:polr1a|POLR1A]]|0.457|
|[[:human genes:r:rpl8|RPL8]]|0.456|
|[[:human genes:d:dhfr|DHFR]]|0.455|
|[[:human genes:n:nol12|NOL12]]|0.455|
|[[:human genes:d:dido1|DIDO1]]|0.455|
|[[:human genes:r:rnpc3|RNPC3]]|0.454|
|[[:human genes:c:cep192|CEP192]]|0.454|
|[[:human genes:g:golga6l3|GOLGA6L3]]|0.454|
|[[:human genes:b:brd2|BRD2]]|0.454|
|[[:human genes:u:uqcrh|UQCRH]]|0.453|
|[[:human genes:i:iscu|ISCU]]|0.453|
|[[:human genes:c:c19orf53|C19orf53]]|0.453|
|[[:human genes:p:pop5|POP5]]|0.452|
|[[:human genes:b:brix1|BRIX1]]|0.452|
|[[:human genes:r:rrp15|RRP15]]|0.451|
|[[:human genes:m:mt1e|MT1E]]|0.451|
|[[:human genes:c:cln6|CLN6]]|0.451|
|[[:human genes:m:mtch2|MTCH2]]|0.451|
|[[:human genes:s:sf3b1|SF3B1]]|0.45|
|[[:human genes:z:znf830|ZNF830]]|0.45|
|[[:human genes:t:taf1|TAF1]]|0.449|
|[[:human genes:n:nupl1|NUPL1]]|0.449|
|[[:human genes:t:twistnb|TWISTNB]]|0.449|
|[[:human genes:r:rbm39|RBM39]]|0.449|
|[[:human genes:c:cdh24|CDH24]]|0.448|
|[[:human genes:p:psmd11|PSMD11]]|0.448|
|[[:human genes:p:ppm1d|PPM1D]]|0.447|
|[[:human genes:d:ddx21|DDX21]]|0.447|
|[[:human genes:c:chchd3|CHCHD3]]|0.447|
|[[:human genes:f:fam160a1|FAM160A1]]|0.446|
|[[:human genes:m:mrs2|MRS2]]|0.446|
|[[:human genes:m:mbtd1|MBTD1]]|0.445|
|[[:human genes:e:exosc3|EXOSC3]]|0.445|
|[[:human genes:u:utp3|UTP3]]|0.444|
|[[:human genes:s:sf3a2|SF3A2]]|0.443|
|[[:human genes:r:rpl12|RPL12]]|0.442|
|[[:human genes:r:rpl17|RPL17]]|0.442|
|[[:human genes:c:cdc45|CDC45]]|0.442|
|[[:human genes:r:rrp9|RRP9]]|0.442|
|[[:human genes:p:paf1|PAF1]]|0.442|
|[[:human genes:p:plk1|PLK1]]|0.441|
|[[:human genes:r:rbm48|RBM48]]|0.441|
|[[:human genes:s:syt9|SYT9]]|0.441|
|[[:human genes:h:hinfp|HINFP]]|0.44|
|[[:human genes:a:atp6v1a|ATP6V1A]]|0.44|
|[[:human genes:m:mki67ip|MKI67IP]]|0.44|
|[[:human genes:t:timeless|TIMELESS]]|0.44|
|[[:human genes:h:hist1h2be|HIST1H2BE]]|0.44|
|[[:human genes:p:pcf11|PCF11]]|0.44|
|[[:human genes:r:rpa2|RPA2]]|0.44|
|[[:human genes:r:riok2|RIOK2]]|0.439|
|[[:human genes:x:xylt2|XYLT2]]|0.438|
|[[:human genes:r:rad21|RAD21]]|0.437|
|[[:human genes:p:polr2a|POLR2A]]|0.437|
|[[:human genes:g:golga6l4|GOLGA6L4]]|0.436|
|[[:human genes:p:polr2f|POLR2F]]|0.435|
|[[:human genes:l:loc643669|LOC643669]]|0.435|
|[[:human genes:s:snip1|SNIP1]]|0.435|
|[[:human genes:a:atp6v0c|ATP6V0C]]|0.434|
|[[:human genes:m:myb|MYB]]|0.433|
|[[:human genes:a:atp6v0b|ATP6V0B]]|0.433|
|[[:human genes:i:imp3|IMP3]]|0.433|
|[[:human genes:g:golga8o|GOLGA8O]]|0.433|
|[[:human genes:n:nol9|NOL9]]|0.433|
|[[:human genes:u:upf1|UPF1]]|0.432|
|[[:human genes:n:nop16|NOP16]]|0.432|
|[[:human genes:f:fbxw9|FBXW9]]|0.432|
|[[:human genes:i:ints5|INTS5]]|0.431|
|[[:human genes:g:gpx4|GPX4]]|0.43|
|[[:human genes:a:aamp|AAMP]]|0.43|
|[[:human genes:m:med14|MED14]]|0.429|
|[[:human genes:t:tpx2|TPX2]]|0.429|
|[[:human genes:h:hgc6.3|HGC6.3]]|0.428|
|[[:human genes:n:npipb8|NPIPB8]]|0.427|
|[[:human genes:r:rpl9|RPL9]]|0.427|
|[[:human genes:n:nsf|NSF]]|0.427|
|[[:human genes:a:ahctf1|AHCTF1]]|0.426|
|[[:human genes:s:s1pr4|S1PR4]]|0.425|
|[[:human genes:p:pde4dip|PDE4DIP]]|0.425|
|[[:human genes:d:dhx38|DHX38]]|0.425|
|[[:human genes:a:ankle2|ANKLE2]]|0.425|
|[[:human genes:t:tp53tg3d|TP53TG3D]]|0.425|
|[[:human genes:c:cgb2|CGB2]]|0.424|
|[[:human genes:c:copb2|COPB2]]|0.424|
|[[:human genes:f:fam86b2|FAM86B2]]|0.424|
|[[:human genes:r:rps3|RPS3]]|0.424|
|[[:human genes:p:polr2i|POLR2I]]|0.424|
|[[:human genes:c:ctr9|CTR9]]|0.423|
|[[:human genes:a:atp6ap1|ATP6AP1]]|0.423|
|[[:human genes:i:ints6|INTS6]]|0.423|
|[[:human genes:r:rrp12|RRP12]]|0.422|
|[[:human genes:n:nup133|NUP133]]|0.422|
|[[:human genes:a:atp13a1|ATP13A1]]|0.422|
|[[:human genes:n:nbpf10|NBPF10]]|0.422|
|[[:human genes:a:arcn1|ARCN1]]|0.422|
|[[:human genes:g:gid4|GID4]]|0.421|
|[[:human genes:p:prpf3|PRPF3]]|0.421|
|[[:human genes:c:chmp4b|CHMP4B]]|0.421|
|[[:human genes:r:rilpl2|RILPL2]]|0.421|
|[[:human genes:s:smc2|SMC2]]|0.42|
|[[:human genes:r:rsl1d1|RSL1D1]]|0.42|
|[[:human genes:d:dimt1|DIMT1]]|0.42|
|[[:human genes:b:bms1|BMS1]]|0.419|
|[[:human genes:t:tyms|TYMS]]|0.419|
|[[:human genes:z:znf541|ZNF541]]|0.419|
|[[:human genes:o:osbp|OSBP]]|0.419|
|[[:human genes:w:wdr46|WDR46]]|0.419|
|[[:human genes:r:rps28|RPS28]]|0.419|
|[[:human genes:x:xab2|XAB2]]|0.418|
|[[:human genes:e:eftud2|EFTUD2]]|0.418|
|[[:human genes:c:cdca5|CDCA5]]|0.418|
|[[:human genes:t:tp53tg3b|TP53TG3B]]|0.418|
|[[:human genes:p:ppie|PPIE]]|0.418|
|[[:human genes:a:ankle1|ANKLE1]]|0.417|
|[[:human genes:t:tp53tg3|TP53TG3]]|0.417|
|[[:human genes:p:pla2g4f|PLA2G4F]]|0.417|
|[[:human genes:t:tp53tg3c|TP53TG3C]]|0.417|
|[[:human genes:m:myo18a|MYO18A]]|0.417|
|[[:human genes:s:sap30bp|SAP30BP]]|0.417|
|[[:human genes:p:prpf8|PRPF8]]|0.417|
|[[:human genes:r:rpl7l1|RPL7L1]]|0.416|
|[[:human genes:n:ngdn|NGDN]]|0.415|
|[[:human genes:s:stil|STIL]]|0.415|
|[[:human genes:e:eif3g|EIF3G]]|0.415|
|[[:human genes:a:akirin2|AKIRIN2]]|0.414|
|[[:human genes:c:ccdc64b|CCDC64B]]|0.414|
|[[:human genes:a:akt1s1|AKT1S1]]|0.414|
|[[:human genes:e:eif4a3|EIF4A3]]|0.413|
|[[:human genes:d:dnm2|DNM2]]|0.413|
|[[:human genes:c:copz1|COPZ1]]|0.413|
|[[:human genes:h:hivep3|HIVEP3]]|0.411|
|[[:human genes:m:mfap1|MFAP1]]|0.411|
|[[:human genes:p:polr2l|POLR2L]]|0.411|
|[[:human genes:t:terf1|TERF1]]|0.411|
|[[:human genes:d:ddx47|DDX47]]|0.411|
|[[:human genes:t:traip|TRAIP]]|0.411|
|[[:human genes:n:nup205|NUP205]]|0.41|
|[[:human genes:n:nup153|NUP153]]|0.409|
|[[:human genes:n:nup43|NUP43]]|0.409|
|[[:human genes:n:napa|NAPA]]|0.409|
|[[:human genes:h:hist2h2aa3|HIST2H2AA3]]|0.409|
|[[:human genes:c:chmp2a|CHMP2A]]|0.409|
|[[:human genes:r:rpl14|RPL14]]|0.408|
|[[:human genes:h:hist2h2aa4|HIST2H2AA4]]|0.408|
|[[:human genes:s:strn|STRN]]|0.408|
|[[:human genes:c:ctage9|CTAGE9]]|0.408|
|[[:human genes:m:med17|MED17]]|0.408|
|[[:human genes:s:snrnp70|SNRNP70]]|0.407|
|[[:human genes:n:nelfcd|NELFCD]]|0.407|
|[[:human genes:y:ythdc1|YTHDC1]]|0.407|
|[[:human genes:a:akap1|AKAP1]]|0.406|
|[[:human genes:g:golga8k|GOLGA8K]]|0.405|
|[[:human genes:c:ccdc94|CCDC94]]|0.405|
|[[:human genes:h:heatr1|HEATR1]]|0.405|
|[[:human genes:m:myo1h|MYO1H]]|0.405|
|[[:human genes:s:smg1|SMG1]]|0.404|
|[[:human genes:t:tsg101|TSG101]]|0.404|
|[[:human genes:d:diexf|DIEXF]]|0.404|
|[[:human genes:m:mcoln1|MCOLN1]]|0.404|
|[[:human genes:c:cacna1a|CACNA1A]]|0.404|
|[[:human genes:f:fam25b|FAM25B]]|0.404|
|[[:human genes:t:terf2|TERF2]]|0.403|
|[[:human genes:o:ogfr|OGFR]]|0.403|
|[[:human genes:c:cdca3|CDCA3]]|0.403|
|[[:human genes:p:psap|PSAP]]|0.402|
|[[:human genes:c:cwc22|CWC22]]|0.402|
|[[:human genes:g:golga6b|GOLGA6B]]|0.401|
|[[:human genes:t:taf15|TAF15]]|0.4|
|[[:human genes:d:disp2|DISP2]]|0.4|
|[[:human genes:p:plekha4|PLEKHA4]]|0.4|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 659/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|1/1|
|909776.0|1/1|
|bile duct|24/28|
|blood|27/28|
|bone|22/26|
|breast|30/33|
|central nervous system|49/56|
|cervix|3/4|
|colorectal|13/17|
|esophagus|11/13|
|fibroblast|1/1|
|gastric|14/16|
|kidney|19/21|
|liver|18/20|
|lung|69/75|
|lymphocyte|15/16|
|ovary|24/26|
|pancreas|21/24|
|peripheral nervous system|16/16|
|plasma cell|15/15|
|prostate|1/1|
|skin|23/24|
|soft tissue|8/9|
|thyroid|2/2|
|upper aerodigestive|18/22|
|urinary tract|26/29|
|uterus|5/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 734
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 8.3 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='RPL35 Expression in NALM6 Cells: 8.3'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>