======= SUPT6H =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: SUPT6H
  * **<color #00a2e8>Official Name</color>**: SPT6 homolog, histone chaperone and transcription elongation factor
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=6830|6830]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q7KZ85|Q7KZ85]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=SUPT6H&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20SUPT6H|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: [[https://omim.org/entry/601333|Open OMIM]]

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='primary' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
|S1|
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|chromatin maintenance|
|negative regulation of histone H3-K27 methylation|
|regulation of mRNA export from nucleus|
|regulation of ribonucleoprotein complex localization|
|regulation of histone H3-K27 methylation|
|regulation of RNA export from nucleus|
|regulation of nucleobase-containing compound transport|
|positive regulation of transcription elongation from RNA polymerase II promoter|
|mRNA transcription by RNA polymerase II|
|negative regulation of histone methylation|
|transcriptionally active chromatin|
|mRNA transcription|
|transcription elongation factor complex|
|nucleosome binding|
|regulation of transcription elongation from RNA polymerase II promoter|
|positive regulation of DNA-templated transcription, elongation|
|regulation of isotype switching|
|blastocyst formation|
|regulation of protein export from nucleus|
|negative regulation of histone modification|
|cellular component maintenance|
|regulation of DNA-templated transcription, elongation|
|regulation of B cell mediated immunity|
|regulation of immunoglobulin mediated immune response|
|negative regulation of chromatin organization|
|regulation of immunoglobulin production|
|regulation of histone methylation|
|transcription elongation from RNA polymerase II promoter|
|DNA-templated transcription, elongation|
|blastocyst development|
|regulation of DNA recombination|
|regulation of nucleocytoplasmic transport|
|histone binding|
|negative regulation of chromosome organization|
|regulation of mRNA processing|
|regulation of production of molecular mediator of immune response|
|regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains|
|regulation of histone modification|
|regulation of lymphocyte mediated immunity|
|regulation of muscle cell differentiation|
|mRNA transport|
|nucleosome organization|
|regulation of adaptive immune response|
|chromatin remodeling|
|regulation of chromatin organization|
|RNA transport|
|nucleic acid transport|
|establishment of RNA localization|
|regulation of leukocyte mediated immunity|
|regulation of B cell activation|
|RNA localization|
|regulation of intracellular protein transport|
|nucleobase-containing compound transport|
|protein-DNA complex subunit organization|
|regulation of mRNA metabolic process|
|regulation of chromosome organization|
|regulation of intracellular transport|
|regulation of DNA metabolic process|
|negative regulation of organelle organization|
|in utero embryonic development|
|RNA splicing|
|regulation of immune effector process|
|mRNA processing|
|transcription by RNA polymerase II|
|regulation of lymphocyte activation|
|regulation of cellular protein localization|
|negative regulation of protein modification process|
|regulation of leukocyte activation|
|chordate embryonic development|
|regulation of cell activation|
|transcription, DNA-templated|
|nucleic acid-templated transcription|
|embryo development ending in birth or egg hatching|
|RNA biosynthetic process|
|DNA-binding transcription factor activity|
|mRNA metabolic process|
|chromatin organization|
|viral process|
|negative regulation of cellular component organization|
|regulation of protein transport|
|regulation of peptide transport|
|regulation of establishment of protein localization|
|symbiotic process|
|interspecies interaction between organisms|
|RNA processing|
|anatomical structure formation involved in morphogenesis|
|regulation of cellular localization|
|embryo development|
|regulation of protein localization|
|negative regulation of cellular protein metabolic process|
|chromosome organization|
|nucleobase-containing compound biosynthetic process|
|negative regulation of protein metabolic process|
|regulation of immune response|
|heterocycle biosynthetic process|
|aromatic compound biosynthetic process|
|positive regulation of transcription by RNA polymerase II|
|regulation of organelle organization|
|organic cyclic compound biosynthetic process|
|RNA binding|
|DNA binding|
|positive regulation of transcription, DNA-templated|
|cellular nitrogen compound biosynthetic process|
|positive regulation of nucleic acid-templated transcription|
|positive regulation of RNA biosynthetic process|
|regulation of immune system process|
|RNA metabolic process|
|cellular macromolecule biosynthetic process|
|positive regulation of RNA metabolic process|
|macromolecule biosynthetic process|
|regulation of cell differentiation|
|regulation of protein modification process|
|nitrogen compound transport|
|protein-containing complex subunit organization|
|regulation of transport|
|positive regulation of nucleobase-containing compound metabolic process|
|positive regulation of macromolecule biosynthetic process|
|positive regulation of cellular biosynthetic process|
|positive regulation of gene expression|
|gene expression|
|positive regulation of biosynthetic process|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp456|Benzoate 20000μM R08 exp456]]|-2.21|
|[[:results:exp199|Etoposide 0.3μM R05 exp199]]|-2.14|
|[[:results:exp223|Cabazitaxel 0.001μM R05 exp223]]|1.7|
|[[:results:exp35|TRAIL 5ng/ml R00 exp35]]|1.74|
|[[:results:exp5|Alpha-Amanitin 0.5μM R00 exp5]]|1.76|
|[[:results:exp16|DABN 2μM R00 exp16]]|1.76|
|[[:results:exp48|Mubritinib 0.2μM R01 exp48]]|1.76|
|[[:results:exp217|Mdivi-1 15μM R05 exp217]]|1.79|
|[[:results:exp241|QNZ 0.01μM R05 exp241]]|1.86|
|[[:results:exp11|CCCP 1μM R00 exp11]]|1.87|
|[[:results:exp235|Geldanamycin 0.01μM R05 exp235]]|1.87|
|[[:results:exp140|Nicotinate 1000μM R03 exp140]]|1.88|
|[[:results:exp38|Wortmannin 5μM R00 exp38]]|1.89|
|[[:results:exp320|ABT-702 5μM plus CoCl2 18μM R07 exp320]]|1.9|
|[[:results:exp54|Taxol 0.002μM R01 exp54]]|1.9|
|[[:results:exp45|Docetaxel 0.002μM R01 exp45]]|1.92|
|[[:results:exp237|NN-Diethyl-meta-toluamide 100μM R05 exp237]]|1.93|
|[[:results:exp122|Golgicide-A 4μM R03 exp122]]|1.93|
|[[:results:exp533|TNF-alpha 44ng/ml R08 exp533]]|1.96|
|[[:results:exp14|Cycloheximide 0.02μM R00 exp14]]|1.97|
|[[:results:exp231|Epothilone-B 0.0015μM R05 exp231]]|2.01|
|[[:results:exp49|NFN1 0.1μM R01 exp49]]|2.01|
|[[:results:exp81|Selumetinib 20μM R02 exp81]]|2.07|
|[[:results:exp18|Doxycycline 10μM R00 exp18]]|2.07|
|[[:results:exp60|Vinblastine 0.002μM R01 exp60]]|2.07|
|[[:results:exp27|Pimelic-diphenylamide-106 0.5μM R00 exp27]]|2.1|
|[[:results:exp220|BAY-598 4μM R05 exp220]]|2.12|
|[[:results:exp209|Deguelin 0.15μM R05 exp209]]|2.19|
|[[:results:exp51|Nifuroxazide 1μM R01 exp51]]|2.24|
|[[:results:exp6|Bortezomib 0.005μM R00 exp6]]|2.26|
|[[:results:exp232|Epothilone-D 0.004 to 0.006μM on day4 R05 exp232]]|2.35|
|[[:results:exp53|Suberoylanilide-Hydroxamic-Acid 0.02μM R01 exp53]]|2.35|
|[[:results:exp149|SB203580 25μM R03 exp149]]|2.35|
|[[:results:exp37|Wortmannin 0.5μM R00 exp37]]|2.35|
|[[:results:exp46|HMS-I1 1μM R01 exp46]]|2.38|
|[[:results:exp40|2-Methoxyestradiol 0.2μM R01 exp40]]|2.54|
|[[:results:exp59|UMK57 1μM R01 exp59]]|2.57|
|[[:results:exp1|5-Fluorouracil 2μM R00 exp1]]|2.67|
|[[:results:exp31|Rifampicin 1μM R00 exp31]]|2.71|
|[[:results:exp102|Nifuroxazide 5μM R03 exp102]]|2.83|
|[[:results:exp23|Nocodazole 0.02μM R00 exp23]]|3.08|
|[[:results:exp12|Chloramphenicol 2μM R00 exp12]]|3.25|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:p:polr2j3|POLR2J3]]|0.579|
|[[:human genes:p:pan2|PAN2]]|0.555|
|[[:human genes:t:tbc1d3c|TBC1D3C]]|0.552|
|[[:human genes:t:tbc1d3g|TBC1D3G]]|0.549|
|[[:human genes:v:vasn|VASN]]|0.548|
|[[:human genes:d:dtl|DTL]]|0.546|
|[[:human genes:z:zfand5|ZFAND5]]|0.542|
|[[:human genes:c:cbwd3|CBWD3]]|0.541|
|[[:human genes:p:psmd3|PSMD3]]|0.54|
|[[:human genes:a:ankle2|ANKLE2]]|0.539|
|[[:human genes:s:ssh2|SSH2]]|0.538|
|[[:human genes:t:tceb3c|TCEB3C]]|0.535|
|[[:human genes:t:tceb3cl2|TCEB3CL2]]|0.535|
|[[:human genes:o:orc1|ORC1]]|0.533|
|[[:human genes:s:supt5h|SUPT5H]]|0.532|
|[[:human genes:c:cope|COPE]]|0.532|
|[[:human genes:t:ticrr|TICRR]]|0.531|
|[[:human genes:p:pan3|PAN3]]|0.529|
|[[:human genes:c:cbwd5|CBWD5]]|0.528|
|[[:human genes:p:psmb4|PSMB4]]|0.527|
|[[:human genes:n:nup205|NUP205]]|0.525|
|[[:human genes:r:rbm39|RBM39]]|0.524|
|[[:human genes:p:psmc6|PSMC6]]|0.523|
|[[:human genes:p:pcf11|PCF11]]|0.523|
|[[:human genes:m:med17|MED17]]|0.52|
|[[:human genes:t:tbc1d3h|TBC1D3H]]|0.517|
|[[:human genes:n:nol10|NOL10]]|0.517|
|[[:human genes:r:rpl14|RPL14]]|0.515|
|[[:human genes:z:znf655|ZNF655]]|0.515|
|[[:human genes:c:c14orf93|C14orf93]]|0.514|
|[[:human genes:z:znf106|ZNF106]]|0.513|
|[[:human genes:r:rad21|RAD21]]|0.512|
|[[:human genes:c:clasp1|CLASP1]]|0.511|
|[[:human genes:t:tceb3cl|TCEB3CL]]|0.51|
|[[:human genes:p:pola2|POLA2]]|0.509|
|[[:human genes:o:orc6|ORC6]]|0.508|
|[[:human genes:r:rpl35|RPL35]]|0.508|
|[[:human genes:c:copb2|COPB2]]|0.507|
|[[:human genes:h:hist1h2be|HIST1H2BE]]|0.505|
|[[:human genes:p:psma6|PSMA6]]|0.504|
|[[:human genes:p:psmd1|PSMD1]]|0.503|
|[[:human genes:d:ddx56|DDX56]]|0.503|
|[[:human genes:c:cdca3|CDCA3]]|0.501|
|[[:human genes:n:nupl1|NUPL1]]|0.498|
|[[:human genes:c:copg1|COPG1]]|0.496|
|[[:human genes:c:ccna2|CCNA2]]|0.496|
|[[:human genes:p:psmb1|PSMB1]]|0.495|
|[[:human genes:h:hist2h2bf|HIST2H2BF]]|0.492|
|[[:human genes:r:rrp15|RRP15]]|0.492|
|[[:human genes:s:sfpq|SFPQ]]|0.491|
|[[:human genes:c:copb1|COPB1]]|0.491|
|[[:human genes:s:smg7|SMG7]]|0.491|
|[[:human genes:n:npipb5|NPIPB5]]|0.49|
|[[:human genes:s:syt9|SYT9]]|0.49|
|[[:human genes:v:vps54|VPS54]]|0.49|
|[[:human genes:c:c1qtnf9b|C1QTNF9B]]|0.489|
|[[:human genes:a:atp6v0c|ATP6V0C]]|0.489|
|[[:human genes:m:myb|MYB]]|0.488|
|[[:human genes:s:sult2b1|SULT2B1]]|0.488|
|[[:human genes:t:tbc1d3e|TBC1D3E]]|0.487|
|[[:human genes:t:tbc1d3k|TBC1D3K]]|0.487|
|[[:human genes:t:tbc1d3i|TBC1D3I]]|0.487|
|[[:human genes:t:tbc1d3l|TBC1D3L]]|0.486|
|[[:human genes:c:cbwd6|CBWD6]]|0.486|
|[[:human genes:m:mt1e|MT1E]]|0.486|
|[[:human genes:r:rad51|RAD51]]|0.484|
|[[:human genes:n:nop16|NOP16]]|0.482|
|[[:human genes:u:upf1|UPF1]]|0.481|
|[[:human genes:k:krt78|KRT78]]|0.481|
|[[:human genes:o:ogfr|OGFR]]|0.48|
|[[:human genes:c:chd4|CHD4]]|0.48|
|[[:human genes:p:psmc1|PSMC1]]|0.48|
|[[:human genes:u:ubap1|UBAP1]]|0.48|
|[[:human genes:g:golga6l6|GOLGA6L6]]|0.479|
|[[:human genes:p:polr1a|POLR1A]]|0.479|
|[[:human genes:a:arcn1|ARCN1]]|0.478|
|[[:human genes:d:ddtl|DDTL]]|0.477|
|[[:human genes:m:mdm2|MDM2]]|0.476|
|[[:human genes:n:nbpf10|NBPF10]]|0.476|
|[[:human genes:a:aamp|AAMP]]|0.476|
|[[:human genes:p:pola1|POLA1]]|0.476|
|[[:human genes:p:psmc2|PSMC2]]|0.476|
|[[:human genes:p:psmc4|PSMC4]]|0.475|
|[[:human genes:a:atxn1|ATXN1]]|0.474|
|[[:human genes:p:psmd6|PSMD6]]|0.474|
|[[:human genes:p:psmd11|PSMD11]]|0.472|
|[[:human genes:p:polr2d|POLR2D]]|0.471|
|[[:human genes:s:scaf1|SCAF1]]|0.47|
|[[:human genes:f:fbxo5|FBXO5]]|0.469|
|[[:human genes:w:wdr43|WDR43]]|0.469|
|[[:human genes:m:med14|MED14]]|0.469|
|[[:human genes:s:sf3a3|SF3A3]]|0.468|
|[[:human genes:r:rnpc3|RNPC3]]|0.467|
|[[:human genes:k:kpnb1|KPNB1]]|0.467|
|[[:human genes:s:slc38a7|SLC38A7]]|0.466|
|[[:human genes:c:cgb2|CGB2]]|0.466|
|[[:human genes:t:twistnb|TWISTNB]]|0.466|
|[[:human genes:w:wdr75|WDR75]]|0.466|
|[[:human genes:r:riok2|RIOK2]]|0.464|
|[[:human genes:g:golga6a|GOLGA6A]]|0.463|
|[[:human genes:t:top1mt|TOP1MT]]|0.461|
|[[:human genes:a:atp6v0b|ATP6V0B]]|0.461|
|[[:human genes:g:gosr2|GOSR2]]|0.461|
|[[:human genes:f:fbxw9|FBXW9]]|0.461|
|[[:human genes:r:rps7|RPS7]]|0.461|
|[[:human genes:r:rps9|RPS9]]|0.46|
|[[:human genes:s:smg1|SMG1]]|0.46|
|[[:human genes:r:rpl26|RPL26]]|0.46|
|[[:human genes:p:polr2j|POLR2J]]|0.46|
|[[:human genes:n:nup155|NUP155]]|0.459|
|[[:human genes:s:slc6a17|SLC6A17]]|0.459|
|[[:human genes:e:exosc5|EXOSC5]]|0.459|
|[[:human genes:r:rps3a|RPS3A]]|0.457|
|[[:human genes:h:hap1|HAP1]]|0.456|
|[[:human genes:l:lad1|LAD1]]|0.454|
|[[:human genes:c:cep192|CEP192]]|0.454|
|[[:human genes:h:hist1h4b|HIST1H4B]]|0.454|
|[[:human genes:y:ythdc1|YTHDC1]]|0.454|
|[[:human genes:t:tbc1d3f|TBC1D3F]]|0.454|
|[[:human genes:c:cdc73|CDC73]]|0.453|
|[[:human genes:n:nup43|NUP43]]|0.453|
|[[:human genes:t:tspy8|TSPY8]]|0.453|
|[[:human genes:m:myo1h|MYO1H]]|0.453|
|[[:human genes:c:copz1|COPZ1]]|0.451|
|[[:human genes:i:iscu|ISCU]]|0.451|
|[[:human genes:a:aqr|AQR]]|0.451|
|[[:human genes:c:cdc45|CDC45]]|0.451|
|[[:human genes:s:slc4a1|SLC4A1]]|0.448|
|[[:human genes:c:cdc6|CDC6]]|0.448|
|[[:human genes:t:tfip11|TFIP11]]|0.446|
|[[:human genes:p:psmd14|PSMD14]]|0.446|
|[[:human genes:k:kmt2a|KMT2A]]|0.446|
|[[:human genes:s:snrpa1|SNRPA1]]|0.445|
|[[:human genes:p:psap|PSAP]]|0.445|
|[[:human genes:p:paf1|PAF1]]|0.445|
|[[:human genes:r:rnf121|RNF121]]|0.444|
|[[:human genes:c:ctage4|CTAGE4]]|0.443|
|[[:human genes:c:cwc22|CWC22]]|0.442|
|[[:human genes:h:hmgcr|HMGCR]]|0.441|
|[[:human genes:t:tbc1d3|TBC1D3]]|0.441|
|[[:human genes:u:uqcrh|UQCRH]]|0.439|
|[[:human genes:r:ranbp2|RANBP2]]|0.438|
|[[:human genes:i:igfn1|IGFN1]]|0.438|
|[[:human genes:p:psmb3|PSMB3]]|0.438|
|[[:human genes:t:traip|TRAIP]]|0.437|
|[[:human genes:a:akirin2|AKIRIN2]]|0.437|
|[[:human genes:d:dnm2|DNM2]]|0.436|
|[[:human genes:n:nup153|NUP153]]|0.436|
|[[:human genes:r:rpl30|RPL30]]|0.435|
|[[:human genes:n:nol12|NOL12]]|0.435|
|[[:human genes:r:rps2|RPS2]]|0.435|
|[[:human genes:c:ccdc94|CCDC94]]|0.434|
|[[:human genes:i:ik|IK]]|0.434|
|[[:human genes:t:timeless|TIMELESS]]|0.433|
|[[:human genes:d:dnttip2|DNTTIP2]]|0.432|
|[[:human genes:r:rrm1|RRM1]]|0.432|
|[[:human genes:d:disp2|DISP2]]|0.432|
|[[:human genes:s:sec13|SEC13]]|0.431|
|[[:human genes:s:stil|STIL]]|0.431|
|[[:human genes:o:osbp|OSBP]]|0.431|
|[[:human genes:r:rps14|RPS14]]|0.43|
|[[:human genes:t:tp53tg3b|TP53TG3B]]|0.429|
|[[:human genes:t:ttc31|TTC31]]|0.429|
|[[:human genes:p:prim1|PRIM1]]|0.429|
|[[:human genes:s:ssfa2|SSFA2]]|0.429|
|[[:human genes:p:plk1|PLK1]]|0.429|
|[[:human genes:z:znf830|ZNF830]]|0.428|
|[[:human genes:r:rps12|RPS12]]|0.428|
|[[:human genes:t:tp53tg3|TP53TG3]]|0.427|
|[[:human genes:h:hist2h3a|HIST2H3A]]|0.426|
|[[:human genes:s:snip1|SNIP1]]|0.426|
|[[:human genes:t:tp53tg3c|TP53TG3C]]|0.426|
|[[:human genes:s:s1pr4|S1PR4]]|0.426|
|[[:human genes:r:rps5|RPS5]]|0.426|
|[[:human genes:a:aatf|AATF]]|0.425|
|[[:human genes:e:exosc9|EXOSC9]]|0.425|
|[[:human genes:h:hivep3|HIVEP3]]|0.425|
|[[:human genes:h:hist2h3c|HIST2H3C]]|0.425|
|[[:human genes:c:ctage9|CTAGE9]]|0.425|
|[[:human genes:r:rfxank|RFXANK]]|0.424|
|[[:human genes:r:rps19bp1|RPS19BP1]]|0.423|
|[[:human genes:a:ahctf1|AHCTF1]]|0.422|
|[[:human genes:m:map7d1|MAP7D1]]|0.422|
|[[:human genes:g:golga8j|GOLGA8J]]|0.422|
|[[:human genes:t:tspy1|TSPY1]]|0.422|
|[[:human genes:m:mfsd12|MFSD12]]|0.422|
|[[:human genes:p:pbxip1|PBXIP1]]|0.422|
|[[:human genes:r:rbbp5|RBBP5]]|0.421|
|[[:human genes:k:kctd17|KCTD17]]|0.421|
|[[:human genes:g:golga8o|GOLGA8O]]|0.421|
|[[:human genes:r:rpl34|RPL34]]|0.421|
|[[:human genes:s:sh3bp1|SH3BP1]]|0.421|
|[[:human genes:l:lrr1|LRR1]]|0.42|
|[[:human genes:a:atp6v1a|ATP6V1A]]|0.419|
|[[:human genes:r:rpl6|RPL6]]|0.419|
|[[:human genes:p:psmd7|PSMD7]]|0.419|
|[[:human genes:r:ruvbl2|RUVBL2]]|0.419|
|[[:human genes:p:polr2a|POLR2A]]|0.419|
|[[:human genes:r:rps28|RPS28]]|0.419|
|[[:human genes:d:dync1i2|DYNC1I2]]|0.417|
|[[:human genes:p:polr2g|POLR2G]]|0.417|
|[[:human genes:t:taf15|TAF15]]|0.417|
|[[:human genes:n:nckap1l|NCKAP1L]]|0.416|
|[[:human genes:g:gprin2|GPRIN2]]|0.415|
|[[:human genes:k:krt2|KRT2]]|0.414|
|[[:human genes:o:or10g3|OR10G3]]|0.413|
|[[:human genes:a:aco2|ACO2]]|0.413|
|[[:human genes:c:cacna1a|CACNA1A]]|0.413|
|[[:human genes:e:exd1|EXD1]]|0.412|
|[[:human genes:v:vps52|VPS52]]|0.411|
|[[:human genes:h:hinfp|HINFP]]|0.411|
|[[:human genes:r:rrp1|RRP1]]|0.411|
|[[:human genes:z:znf513|ZNF513]]|0.411|
|[[:human genes:n:nup54|NUP54]]|0.411|
|[[:human genes:t:taf1|TAF1]]|0.41|
|[[:human genes:p:pigs|PIGS]]|0.41|
|[[:human genes:c:cdt1|CDT1]]|0.41|
|[[:human genes:p:psma7|PSMA7]]|0.41|
|[[:human genes:c:cox8a|COX8A]]|0.409|
|[[:human genes:t:tsg101|TSG101]]|0.409|
|[[:human genes:r:rrn3|RRN3]]|0.408|
|[[:human genes:f:fam160a1|FAM160A1]]|0.408|
|[[:human genes:c:chmp2a|CHMP2A]]|0.407|
|[[:human genes:n:nup214|NUP214]]|0.406|
|[[:human genes:r:rfpl3|RFPL3]]|0.406|
|[[:human genes:u:utp3|UTP3]]|0.406|
|[[:human genes:u:utp20|UTP20]]|0.406|
|[[:human genes:e:eif4a3|EIF4A3]]|0.406|
|[[:human genes:c:chmp4b|CHMP4B]]|0.405|
|[[:human genes:s:sema6b|SEMA6B]]|0.405|
|[[:human genes:c:ckap5|CKAP5]]|0.404|
|[[:human genes:p:psmb2|PSMB2]]|0.404|
|[[:human genes:n:narfl|NARFL]]|0.404|
|[[:human genes:p:pde4dip|PDE4DIP]]|0.404|
|[[:human genes:r:rffl|RFFL]]|0.404|
|[[:human genes:r:rpl9|RPL9]]|0.403|
|[[:human genes:b:bcl2l1|BCL2L1]]|0.402|
|[[:human genes:r:rpl7l1|RPL7L1]]|0.402|
|[[:human genes:c:cln6|CLN6]]|0.401|
|[[:human genes:m:med29|MED29]]|0.401|
|[[:human genes:m:myh2|MYH2]]|0.401|
|[[:human genes:d:dgcr14|DGCR14]]|0.401|
|[[:human genes:f:fbl|FBL]]|0.401|
|[[:human genes:a:atp6v1c1|ATP6V1C1]]|0.4|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 723/726
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|1/1|
|909776.0|1/1|
|bile duct|27/28|
|blood|28/28|
|bone|25/25|
|breast|33/33|
|central nervous system|55/56|
|cervix|4/4|
|colorectal|16/17|
|esophagus|13/13|
|fibroblast|1/1|
|gastric|15/15|
|kidney|21/21|
|liver|20/20|
|lung|75/75|
|lymphocyte|14/14|
|ovary|26/26|
|pancreas|24/24|
|peripheral nervous system|16/16|
|plasma cell|15/15|
|prostate|1/1|
|skin|24/24|
|soft tissue|7/7|
|thyroid|2/2|
|upper aerodigestive|22/22|
|urinary tract|29/29|
|uterus|5/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 93
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 7.64 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='SUPT6H Expression in NALM6 Cells: 7.64'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>