====== Ixabepilone 0.004 to 0.005μM on day4 R04 exp184 ======
==== Mechanism of Action ====
Inhibits microtubule depolymerization, semi-synthetic analog of epothilone
  * **<color #00a2e8>Class / Subclass 1:</color>** Cell Cycle / Microtubule Poison
  * **<color #00a2e8>Class / Subclass 2:</color>** Organelle Function / Cytoskeletal Inhibitor



==== Technical Notes ====
<accordion collapsed='true'>
<panel title='Compound References' collapsed='true'>
    * **<color #00a2e8>PubChem Name:</color>** %%Ixabepilone%%
    * **<color #00a2e8>Synonyms:</color>** Azaepothilone B; BMS 247550; BMS 247550-1
    * **<color #00a2e8>CAS #:</color>** 219989-84-1
    * **<color #00a2e8>PubChem CID:</color>** [[https://pubchem.ncbi.nlm.nih.gov/compound/6445540|6445540]]
    * **<color #00a2e8>IUPAC:</color>** %%(1S,3S,7S,10R,11S,12S,16R)-7,11-dihydroxy-8,8,10,12,16-pentamethyl-3-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-17-oxa-4-azabicyclo[14.1.0]heptadecane-5,9-dione%%
    * **<color #00a2e8>INCHI Name:</color>** InChI=1S/C27H42N2O5S/c1-15-9-8-10-27(7)22(34-27)12-20(16(2)11-19-14-35-18(4)28-19)29-23(31)13-21(30)26(5,6)25(33)17(3)24(15)32/h11,14-15,17,20-22,24,30,32H,8-10,12-13H2,1-7H3,(H,29,31)/b16-11+/t15-,17+,20-,21-,22-,24-,27+/m0/s1
    * **<color #00a2e8>INCHI Key:</color>** FABUFPQFXZVHFB-PVYNADRNSA-N
    * **<color #00a2e8>Molecular Weight:</color>** 506.7
    * **<color #00a2e8>Canonical SMILES:</color>** CC1CCCC2(C(O2)CC(NC(=O)CC(C(C(=O)C(C1O)C)(C)C)O)C(=CC3=CSC(=N3)C)C)C
    * **<color #00a2e8>Isomeric SMILES:</color>** C[C@H]1CCC[C@@]2([C@@H](O2)C[C@H](NC(=O)C[C@@H](C(C(=O)[C@@H]([C@H]1O)C)(C)C)O)/C(=C/C3=CSC(=N3)C)/C)C
    * **<color #00a2e8>Molecular Formula:</color>** C27H42N2O5S
{{:chemogenomics:structures:chem-0117.svg?nolink}}
</panel>


<panel title='Compound Supplier' collapsed='true'>
    * **<color #00a2e8>Supplier Name:</color>** Toronto Research Chemicals
    * **<color #00a2e8>Catalog #:</color>** I941990
    * **<color #00a2e8>Lot #:</color>** N/A
</panel>


<panel title='Compound Characterization' collapsed='true'>
    * **<color #00a2e8>HRMS (ESI-TOF) m/z:</color>** (M+H)+ Calcd for C27H42N2O5S 507.28872; found 507.28672
</panel>


<panel title='Dose Response Curve' collapsed='true'>
    * **<color #00a2e8>Platform ID:</color>** Ixabepilone
    * **<color #00a2e8>Min:</color>** -4.1980; **<color #00a2e8>Max:</color>** 87.9090
{{:chemogenomics:dose_response:dr_227.png?nolink&500 |}}
\\ 
\\ 
\\ 
\\ 
|< 300px 100px 200px >|
^ IC   ^ Concentration (µM) ^
| IC10  |N/A    |
| IC20  |0.0030    |
| IC30  |0.0036    |
| IC40  |0.0043    |
| IC50  |0.0050    |
| IC60  |N/A    |
| IC70  |N/A    |
| IC80  |N/A    |
| IC90  |N/A    |
\\ 
</panel>
</accordion>
==== Screen Summary ====
    * **<color #00a2e8>Round</color>**: 04
    * **<color #00a2e8>Dose</color>**: 0.004-0.005µM
    * **<color #00a2e8>Days of incubation</color>**: 8
    * **<color #00a2e8>Doublings</color>**: 6.1
    * **<color #00a2e8>Numbers of reads</color>**: 21290000


==== Screen Results ====


^Sensitive/Resistant hits (FDR<0.05)^CRANKS^Score Plot^Top 30 Genes^Screen Similarity^Top 30 Sensitive GO terms^Top 30 Resistant GO terms^
|35/7|<color #e85500>[[https://files.tyerslab.com/files/public/chemogenomics/cranks/Ixabepilone_0.004-0.005day4uM_Round-4_exp184.txt|Scores]]</color>|<button type="primary" size="sm" modal="ScorePlot">View</button>|<button type="primary" size="sm" modal="modal_hits">View</button>|<button type="primary" size="sm" modal="modal_screen_similarity">View</button>|<button type="primary" size="sm" modal="modal_go_sensitive">View</button>|<button type="default" size="sm" modal="modal_go_resistant">View</button>|
<modal id='ScorePlot' size='lg' title='Ixabepilone 0.004 to 0.005μM on day4 R04 exp184'>
{{:chemogenomics:cranks_plots:exp184.png?nolink}}
</modal>


<modal id="modal_hits" size="sm" title="Top 30 S/R Genes">
^Gene^CRANKS Score^FDR^
|[[:human_genes:K:KIF18B|KIF18B]]|-4.56|<0.01|
|[[:human_genes:M:MSI2|MSI2]]|-3.85|<0.01|
|[[:human_genes:K:KIF4A|KIF4A]]|-3.78|<0.01|
|[[:human_genes:S:SEPHS1|SEPHS1]]|-3.59|<0.01|
|[[:human_genes:K:KNTC1|KNTC1]]|-3.40|<0.01|
|[[:human_genes:T:TACC3|TACC3]]|-3.25|<0.01|
|[[:human_genes:N:NPRL3|NPRL3]]|-3.20|<0.01|
|[[:human_genes:K:KIF2C|KIF2C]]|-3.20|<0.01|
|[[:human_genes:K:KATNB1|KATNB1]]|-3.19|<0.01|
|[[:human_genes:K:KATNA1|KATNA1]]|-3.01|<0.01|
|[[:human_genes:N:NPRL2|NPRL2]]|-2.99|<0.01|
|[[:human_genes:D:DLGAP5|DLGAP5]]|-2.95|<0.01|
|[[:human_genes:Q:QRICH1|QRICH1]]|-2.91|0.01|
|[[:human_genes:S:SEPSECS|SEPSECS]]|-2.90|<0.01|
|[[:human_genes:G:GNA13|GNA13]]|-2.81|<0.01|
|[[:human_genes:T:TRIP13|TRIP13]]|-2.77|0.01|
|[[:human_genes:F:FBXW7|FBXW7]]|-2.75|<0.01|
|[[:human_genes:T:TCF4|TCF4]]|-2.71|<0.01|
|[[:human_genes:I:ILF3|ILF3]]|-2.69|0.21|
|[[:human_genes:A:ATP2B1|ATP2B1]]|-2.66|0.02|
|[[:human_genes:D:DDX3X|DDX3X]]|-2.64|<0.01|
|[[:human_genes:U:UBE4B|UBE4B]]|-2.50|0.02|
|[[:human_genes:C:CCNB1|CCNB1]]|-2.49|0.03|
|[[:human_genes:P:PDCD2L|PDCD2L]]|-2.46|0.02|
|[[:human_genes:M:MCM9|MCM9]]|-2.45|0.02|
|[[:human_genes:G:GTSE1|GTSE1]]|-2.45|0.04|
|[[:human_genes:I:IPPK|IPPK]]|-2.43|0.02|
|[[:human_genes:G:GAK|GAK]]|-2.42|0.02|
|[[:human_genes:C:C12orf66|C12orf66]]|-2.41|0.03|
|[[:human_genes:S:SOD1|SOD1]]|-2.38|0.05|
|[[:human_genes:C:CDC26|CDC26]]|2.01|0.44|
|[[:human_genes:S:SPATA32|SPATA32]]|2.03|0.30|
|[[:human_genes:T:TM2D1|TM2D1]]|2.03|0.44|
|[[:human_genes:P:PRPF8|PRPF8]]|2.03|0.65|
|[[:human_genes:X:XPO4|XPO4]]|2.05|0.30|
|[[:human_genes:C:C11orf95|C11orf95]]|2.06|0.51|
|[[:human_genes:C:CLPB|CLPB]]|2.06|0.30|
|[[:human_genes:F:FAM153A|FAM153A]]|2.08|0.30|
|[[:human_genes:T:TUBA1B|TUBA1B]]|2.08|0.47|
|[[:human_genes:C:CCDC94|CCDC94]]|2.14|0.55|
|[[:human_genes:Z:ZNRF4|ZNRF4]]|2.15|0.22|
|[[:human_genes:M:MDH1|MDH1]]|2.16|0.30|
|[[:human_genes:M:MOB2|MOB2]]|2.16|0.30|
|[[:human_genes:G:GABARAPL1|GABARAPL1]]|2.17|0.22|
|[[:human_genes:P:POC5|POC5]]|2.19|0.22|
|[[:human_genes:N:NUP88|NUP88]]|2.23|0.38|
|[[:human_genes:L:LYG2|LYG2]]|2.29|0.22|
|[[:human_genes:S:SMARCC1|SMARCC1]]|2.32|0.11|
|[[:human_genes:E:EFNA5|EFNA5]]|2.40|0.08|
|[[:human_genes:F:FEZF2|FEZF2]]|2.44|0.07|
|[[:human_genes:M:ME2|ME2]]|2.61|0.03|
|[[:human_genes:C:C18orf32|C18orf32]]|2.62|0.48|
|[[:human_genes:R:RPL34|RPL34]]|2.68|0.30|
|[[:human_genes:X:XAB2|XAB2]]|2.77|0.44|
|[[:human_genes:S:SLAIN1|SLAIN1]]|2.81|0.03|
|[[:human_genes:S:SAMHD1|SAMHD1]]|2.95|0.02|
|[[:human_genes:K:KIFC1|KIFC1]]|2.97|<0.01|
|[[:human_genes:T:TP53|TP53]]|3.05|<0.01|
|[[:human_genes:C:CLASP1|CLASP1]]|3.36|<0.01|
|[[:human_genes:T:TUBB4B|TUBB4B]]|3.75|<0.01|
</modal>


<modal id="modal_screen_similarity" size="lg" title="Correlated Screens">
^Screen^Correlation^Plot^
|[[:results:exp103|Taxol 0.004μM R03 exp103]]|0.181|<button type="primary" size="small" modal="1">View</button>|
|[[:results:exp190|Vincristine 0.0005μM R04 exp190]]|0.117|<button type="primary" size="small" modal="2">View</button>|
|[[:results:exp517|Quercetin 20μM R08 exp517]]|0.088|<button type="primary" size="small" modal="3">View</button>|
|[[:results:exp217|Mdivi-1 15μM R05 exp217]]|0.083|<button type="primary" size="small" modal="4">View</button>|
|[[:results:exp243|S-trityl-L-cysteine 0.5μM R05 exp243]]|0.079|<button type="primary" size="small" modal="5">View</button>|
|[[:results:exp59|UMK57 1μM R01 exp59]]|0.074|<button type="primary" size="small" modal="6">View</button>|
|[[:results:exp60|Vinblastine 0.002μM R01 exp60]]|0.067|<button type="primary" size="small" modal="7">View</button>|
|[[:results:exp107|UMK57 0.6μM R03 exp107]]|0.067|<button type="primary" size="small" modal="8">View</button>|
|[[:results:exp526|Sulforaphane 9μM R08 exp526 no dilution day6]]|0.058|<button type="primary" size="small" modal="9">View</button>|
|[[:results:exp54|Taxol 0.002μM R01 exp54]]|0.056|<button type="primary" size="small" modal="10">View</button>|
|[[:results:exp525|Sulforaphane 9μM R08 exp525]]|0.056|<button type="primary" size="small" modal="11">View</button>|
|[[:results:exp187|proTAME 5μM R04 exp187]]|0.054|<button type="primary" size="small" modal="12">View</button>|
|[[:results:exp299|Talazoparib 0.006μM R06 exp299]]|0.052|<button type="primary" size="small" modal="13">View</button>|
|[[:results:exp231|Epothilone-B 0.0015μM R05 exp231]]|0.16|<button type="primary" size="small" modal="14">View</button>|
|[[:results:exp223|Cabazitaxel 0.001μM R05 exp223]]|0.141|<button type="primary" size="small" modal="15">View</button>|
|[[:results:exp179|Combretastatin A4 0.002 to 0.003μM day4 R04 exp179]]|0.11|<button type="primary" size="small" modal="16">View</button>|
|[[:results:exp159|Docetaxel 0.001 to 0.002μM on day4 R04 exp159]]|0.106|<button type="primary" size="small" modal="17">View</button>|
|[[:results:exp460|BML-284 0.09μM R08 exp460]]|0.104|<button type="primary" size="small" modal="18">View</button>|
|[[:results:exp45|Docetaxel 0.002μM R01 exp45]]|0.079|<button type="primary" size="small" modal="19">View</button>|
|[[:results:exp311|2-Methoxyestradiol 0.55 to 0.75μM  on day4 R07 exp311]]|0.079|<button type="primary" size="small" modal="20">View</button>|
|[[:results:exp228|Demecolcine 0.03μM R05 exp228]]|0.075|<button type="primary" size="small" modal="21">View</button>|
|[[:results:exp232|Epothilone-D 0.004 to 0.006μM on day4 R05 exp232]]|0.073|<button type="primary" size="small" modal="22">View</button>|
|[[:results:exp310|2-Methoxyestradiol 0.55μM R07 exp310]]|0.069|<button type="primary" size="small" modal="23">View</button>|
|[[:results:exp215|Colchicine 0.009μM R05 exp215]]|0.066|<button type="primary" size="small" modal="24">View</button>|
|[[:results:exp312|2-Methoxyestradiol 0.55 to 1μM on day4 R07 exp312]]|0.063|<button type="primary" size="small" modal="25">View</button>|
|[[:results:exp162|BI-D1870 2μM R04 exp162]]|0.06|<button type="primary" size="small" modal="26">View</button>|
|[[:results:exp46|HMS-I1 1μM R01 exp46]]|0.059|<button type="primary" size="small" modal="27">View</button>|
|[[:results:exp5|Alpha-Amanitin 0.5μM R00 exp5]]|0.057|<button type="primary" size="small" modal="28">View</button>|
|[[:results:exp360|Genistein 15μM R07 exp360]]|0.052|<button type="primary" size="small" modal="29">View</button>|
</modal>


<modal id="1" size="lg" title="Ixabepilone 0.004 to 0.005μM on day4 R04 exp184  vs  Taxol 0.004μM R03 exp103">
{{:chemogenomics:comparison_plots:exp103_vs_exp184.png?nolink |}}
</modal>

<modal id="2" size="lg" title="Ixabepilone 0.004 to 0.005μM on day4 R04 exp184  vs  Vincristine 0.0005μM R04 exp190">
{{:chemogenomics:comparison_plots:exp184_vs_exp190.png?nolink |}}
</modal>

<modal id="3" size="lg" title="Ixabepilone 0.004 to 0.005μM on day4 R04 exp184  vs  Quercetin 20μM R08 exp517">
{{:chemogenomics:comparison_plots:exp184_vs_exp517.png?nolink |}}
</modal>

<modal id="4" size="lg" title="Ixabepilone 0.004 to 0.005μM on day4 R04 exp184  vs  Mdivi-1 15μM R05 exp217">
{{:chemogenomics:comparison_plots:exp184_vs_exp217.png?nolink |}}
</modal>

<modal id="5" size="lg" title="Ixabepilone 0.004 to 0.005μM on day4 R04 exp184  vs  S-trityl-L-cysteine 0.5μM R05 exp243">
{{:chemogenomics:comparison_plots:exp184_vs_exp243.png?nolink |}}
</modal>

<modal id="6" size="lg" title="Ixabepilone 0.004 to 0.005μM on day4 R04 exp184  vs  UMK57 1μM R01 exp59">
{{:chemogenomics:comparison_plots:exp184_vs_exp59.png?nolink |}}
</modal>

<modal id="7" size="lg" title="Ixabepilone 0.004 to 0.005μM on day4 R04 exp184  vs  Vinblastine 0.002μM R01 exp60">
{{:chemogenomics:comparison_plots:exp184_vs_exp60.png?nolink |}}
</modal>

<modal id="8" size="lg" title="Ixabepilone 0.004 to 0.005μM on day4 R04 exp184  vs  UMK57 0.6μM R03 exp107">
{{:chemogenomics:comparison_plots:exp107_vs_exp184.png?nolink |}}
</modal>

<modal id="9" size="lg" title="Ixabepilone 0.004 to 0.005μM on day4 R04 exp184  vs  Sulforaphane 9μM R08 exp526 no dilution day6">
{{:chemogenomics:comparison_plots:exp184_vs_exp526.png?nolink |}}
</modal>

<modal id="10" size="lg" title="Ixabepilone 0.004 to 0.005μM on day4 R04 exp184  vs  Taxol 0.002μM R01 exp54">
{{:chemogenomics:comparison_plots:exp184_vs_exp54.png?nolink |}}
</modal>

<modal id="11" size="lg" title="Ixabepilone 0.004 to 0.005μM on day4 R04 exp184  vs  Sulforaphane 9μM R08 exp525">
{{:chemogenomics:comparison_plots:exp184_vs_exp525.png?nolink |}}
</modal>

<modal id="12" size="lg" title="Ixabepilone 0.004 to 0.005μM on day4 R04 exp184  vs  proTAME 5μM R04 exp187">
{{:chemogenomics:comparison_plots:exp184_vs_exp187.png?nolink |}}
</modal>

<modal id="13" size="lg" title="Ixabepilone 0.004 to 0.005μM on day4 R04 exp184  vs  Talazoparib 0.006μM R06 exp299">
{{:chemogenomics:comparison_plots:exp184_vs_exp299.png?nolink |}}
</modal>

<modal id="14" size="lg" title="Epothilone-B 0.0015μM R05 exp231  vs  Ixabepilone 0.004 to 0.005μM on day4 R04 exp184">
{{:chemogenomics:comparison_plots:exp184_vs_exp231.png?nolink |}}
</modal>

<modal id="15" size="lg" title="Cabazitaxel 0.001μM R05 exp223  vs  Ixabepilone 0.004 to 0.005μM on day4 R04 exp184">
{{:chemogenomics:comparison_plots:exp184_vs_exp223.png?nolink |}}
</modal>

<modal id="16" size="lg" title="Combretastatin A4 0.002 to 0.003μM day4 R04 exp179  vs  Ixabepilone 0.004 to 0.005μM on day4 R04 exp184">
{{:chemogenomics:comparison_plots:exp179_vs_exp184.png?nolink |}}
</modal>

<modal id="17" size="lg" title="Docetaxel 0.001 to 0.002μM on day4 R04 exp159  vs  Ixabepilone 0.004 to 0.005μM on day4 R04 exp184">
{{:chemogenomics:comparison_plots:exp159_vs_exp184.png?nolink |}}
</modal>

<modal id="18" size="lg" title="BML-284 0.09μM R08 exp460  vs  Ixabepilone 0.004 to 0.005μM on day4 R04 exp184">
{{:chemogenomics:comparison_plots:exp184_vs_exp460.png?nolink |}}
</modal>

<modal id="19" size="lg" title="Docetaxel 0.002μM R01 exp45  vs  Ixabepilone 0.004 to 0.005μM on day4 R04 exp184">
{{:chemogenomics:comparison_plots:exp184_vs_exp45.png?nolink |}}
</modal>

<modal id="20" size="lg" title="2-Methoxyestradiol 0.55 to 0.75μM  on day4 R07 exp311  vs  Ixabepilone 0.004 to 0.005μM on day4 R04 exp184">
{{:chemogenomics:comparison_plots:exp184_vs_exp311.png?nolink |}}
</modal>

<modal id="21" size="lg" title="Demecolcine 0.03μM R05 exp228  vs  Ixabepilone 0.004 to 0.005μM on day4 R04 exp184">
{{:chemogenomics:comparison_plots:exp184_vs_exp228.png?nolink |}}
</modal>

<modal id="22" size="lg" title="Epothilone-D 0.004 to 0.006μM on day4 R05 exp232  vs  Ixabepilone 0.004 to 0.005μM on day4 R04 exp184">
{{:chemogenomics:comparison_plots:exp184_vs_exp232.png?nolink |}}
</modal>

<modal id="23" size="lg" title="2-Methoxyestradiol 0.55μM R07 exp310  vs  Ixabepilone 0.004 to 0.005μM on day4 R04 exp184">
{{:chemogenomics:comparison_plots:exp184_vs_exp310.png?nolink |}}
</modal>

<modal id="24" size="lg" title="Colchicine 0.009μM R05 exp215  vs  Ixabepilone 0.004 to 0.005μM on day4 R04 exp184">
{{:chemogenomics:comparison_plots:exp184_vs_exp215.png?nolink |}}
</modal>

<modal id="25" size="lg" title="2-Methoxyestradiol 0.55 to 1μM on day4 R07 exp312  vs  Ixabepilone 0.004 to 0.005μM on day4 R04 exp184">
{{:chemogenomics:comparison_plots:exp184_vs_exp312.png?nolink |}}
</modal>

<modal id="26" size="lg" title="BI-D1870 2μM R04 exp162  vs  Ixabepilone 0.004 to 0.005μM on day4 R04 exp184">
{{:chemogenomics:comparison_plots:exp162_vs_exp184.png?nolink |}}
</modal>

<modal id="27" size="lg" title="HMS-I1 1μM R01 exp46  vs  Ixabepilone 0.004 to 0.005μM on day4 R04 exp184">
{{:chemogenomics:comparison_plots:exp184_vs_exp46.png?nolink |}}
</modal>

<modal id="28" size="lg" title="Alpha-Amanitin 0.5μM R00 exp5  vs  Ixabepilone 0.004 to 0.005μM on day4 R04 exp184">
{{:chemogenomics:comparison_plots:exp184_vs_exp5.png?nolink |}}
</modal>

<modal id="29" size="lg" title="Genistein 15μM R07 exp360  vs  Ixabepilone 0.004 to 0.005μM on day4 R04 exp184">
{{:chemogenomics:comparison_plots:exp184_vs_exp360.png?nolink |}}
</modal>



<modal id="modal_go_sensitive" size="lg" title="Top 30 sensitive GO terms">
^GO Term^Fold Change^Genes^
|protein depolymerization|64.62|KIF18B,KIF2C,KATNB1,GAK|
|mitotic sister chromatid segregation|31.36|KIF18B,KIF4A,KNTC1,KIF2C,KATNB1,DLGAP5,CCNB1|
|sister chromatid segregation|30.47|KIF18B,KIF4A,KNTC1,KIF2C,KATNB1,DLGAP5,CCNB1|
|regulation of sister chromatid segregation|29.80|KNTC1,TACC3,DLGAP5,TRIP13,CCNB1|
|mitotic nuclear division|26.20|KIF18B,KIF4A,KNTC1,KIF2C,KATNB1,DLGAP5,CCNB1|
|nuclear chromosome segregation|22.32|KIF18B,KIF4A,KNTC1,KIF2C,KATNB1,DLGAP5,TRIP13,CCNB1|
|spindle pole|21.67|KNTC1,TACC3,KATNB1,KATNA1,DLGAP5,CCNB1|
|chromosome segregation|16.84|KIF18B,KIF4A,KNTC1,KIF2C,KATNB1,DLGAP5,TRIP13,DDX3X,CCNB1|
|microtubule binding|16.21|KIF18B,KIF4A,KIF2C,KATNB1,KATNA1,DLGAP5,GTSE1|
|nuclear division|16.15|KIF18B,KIF4A,KNTC1,KIF2C,KATNB1,DLGAP5,TRIP13,CCNB1|
|chromosome organization|15.31|KIF18B,KIF4A,KNTC1,KIF2C,KATNB1,DLGAP5,TRIP13,FBXW7,DDX3X,CCNB1,MCM9|
|organelle fission|14.93|KIF18B,KIF4A,KNTC1,KIF2C,KATNB1,DLGAP5,TRIP13,CCNB1|
|tubulin binding|13.45|KIF18B,KIF4A,KIF2C,KATNB1,KATNA1,DLGAP5,DDX3X,GTSE1|
|spindle|13.31|KIF18B,KIF4A,KNTC1,TACC3,KIF2C,KATNB1,KATNA1,DLGAP5,CCNB1|
|mitotic cell cycle process|11.87|KIF18B,KIF4A,KNTC1,TACC3,KIF2C,KATNB1,DLGAP5,TRIP13,CCNB1,GTSE1|
|mitotic cell cycle|10.21|KIF18B,KIF4A,KNTC1,TACC3,KIF2C,KATNB1,DLGAP5,TRIP13,CCNB1,GTSE1|
|cell division|9.71|KIF18B,KIF4A,KNTC1,TACC3,KIF2C,KATNB1,KATNA1,CCNB1|
|cell cycle process|8.44|KIF18B,KIF4A,KNTC1,TACC3,KIF2C,KATNB1,DLGAP5,TRIP13,FBXW7,DDX3X,CCNB1,GTSE1|
|regulation of cell cycle process|8.00|KNTC1,TACC3,KIF2C,DLGAP5,TRIP13,FBXW7,DDX3X,CCNB1,GTSE1|
</modal>
<modal id="modal_go_resistant" size="lg" title="Top 30 resistant GO terms">No GO term hits below threshold. (FDR <0.05)</modal>