====== Quercetin 20μM R08 exp517 ======
==== Mechanism of Action ====
General kinase inhibitor, may inhibit NF-‘_B, anti-oxidant, putative senolytic
  * **<color #00a2e8>Class / Subclass 1:</color>** Signal Transduction / Kinase Inhibitor
  * **<color #00a2e8>Class / Subclass 2:</color>** Gene Regulation / Transcription Inhibitor
  * **<color #00a2e8>Class / Subclass 3:</color>** Uncharacterized Mechanism / Natural Product


==== Technical Notes ====
<accordion collapsed='true'>
<panel title='Compound References' collapsed='true'>
    * **<color #00a2e8>PubChem Name:</color>** %%Quercetin dihydrate%%
    * **<color #00a2e8>Synonyms:</color>** N/A
    * **<color #00a2e8>CAS #:</color>** 6151-25-3
    * **<color #00a2e8>PubChem CID:</color>** [[https://pubchem.ncbi.nlm.nih.gov/compound/5284452|5284452]]
    * **<color #00a2e8>IUPAC:</color>** %%2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one;dihydrate%%
    * **<color #00a2e8>INCHI Name:</color>** InChI=1S/C15H10O7.2H2O/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6;;/h1-5,16-19,21H;2*1H2
    * **<color #00a2e8>INCHI Key:</color>** GMGIWEZSKCNYSW-UHFFFAOYSA-N
    * **<color #00a2e8>Molecular Weight:</color>** 338.27
    * **<color #00a2e8>Canonical SMILES:</color>** C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O.O.O
    * **<color #00a2e8>Isomeric SMILES:</color>** N/A
    * **<color #00a2e8>Molecular Formula:</color>** C15H14O9
{{:chemogenomics:structures:chem-0322.svg?nolink}}
</panel>


<panel title='Compound Supplier' collapsed='true'>
    * **<color #00a2e8>Supplier Name:</color>** Sigma-Aldrich
    * **<color #00a2e8>Catalog #:</color>** Q0125
    * **<color #00a2e8>Lot #:</color>** 113K1051
</panel>


<panel title='Compound Characterization' collapsed='true'>
Characterization data not available.
</panel>


<panel title='Dose Response Curve' collapsed='true'>
    * **<color #00a2e8>Platform ID:</color>** Quercetin
    * **<color #00a2e8>Min:</color>** -18.5542; **<color #00a2e8>Max:</color>** 12.6779
{{:chemogenomics:dose_response:dr_572.png?nolink&500 |}}
\\ 
\\ 
\\ 
\\ 
|< 300px 100px 200px >|
^ IC   ^ Concentration (µM) ^
| IC10  |N/A    |
| IC20  |N/A    |
| IC30  |N/A    |
| IC40  |N/A    |
| IC50  |N/A    |
| IC60  |N/A    |
| IC70  |N/A    |
| IC80  |N/A    |
| IC90  |N/A    |
\\ 
</panel>
</accordion>
==== Screen Summary ====
    * **<color #00a2e8>Round</color>**: 08
    * **<color #00a2e8>Dose</color>**: 20µM
    * **<color #00a2e8>Days of incubation</color>**: 8
    * **<color #00a2e8>Doublings</color>**: 3.4
    * **<color #00a2e8>Numbers of reads</color>**: 18650040


==== Screen Results ====


^Sensitive/Resistant hits (FDR<0.05)^CRANKS^Score Plot^Top 30 Genes^Screen Similarity^Top 30 Sensitive GO terms^Top 30 Resistant GO terms^
|43/17|<color #e85500>[[https://files.tyerslab.com/files/public/chemogenomics/cranks/Quercetin_20uM_Round-8_exp517.txt|Scores]]</color>|<button type="primary" size="sm" modal="ScorePlot">View</button>|<button type="primary" size="sm" modal="modal_hits">View</button>|<button type="primary" size="sm" modal="modal_screen_similarity">View</button>|<button type="primary" size="sm" modal="modal_go_sensitive">View</button>|<button type="primary" size="sm" modal="modal_go_resistant">View</button>|
<modal id='ScorePlot' size='lg' title='Quercetin 20μM R08 exp517'>
{{:chemogenomics:cranks_plots:exp517.png?nolink}}
</modal>


<modal id="modal_hits" size="sm" title="Top 30 S/R Genes">
^Gene^CRANKS Score^FDR^
|[[:human_genes:G:GAK|GAK]]|-3.44|<0.01|
|[[:human_genes:B:BRD1|BRD1]]|-3.07|<0.01|
|[[:human_genes:M:MCM9|MCM9]]|-3.05|<0.01|
|[[:human_genes:C:CNOT8|CNOT8]]|-3.03|<0.01|
|[[:human_genes:R:RPS15A|RPS15A]]|-3.01|0.20|
|[[:human_genes:T:TCF4|TCF4]]|-2.98|<0.01|
|[[:human_genes:N:NPRL3|NPRL3]]|-2.96|0.01|
|[[:human_genes:P:PCGF1|PCGF1]]|-2.96|<0.01|
|[[:human_genes:S:SEPHS1|SEPHS1]]|-2.90|<0.01|
|[[:human_genes:B:BCL2|BCL2]]|-2.88|<0.01|
|[[:human_genes:C:CNOT2|CNOT2]]|-2.87|<0.01|
|[[:human_genes:G:GTSE1|GTSE1]]|-2.86|<0.01|
|[[:human_genes:R:RANBP1|RANBP1]]|-2.83|<0.01|
|[[:human_genes:N:NPRL2|NPRL2]]|-2.74|0.03|
|[[:human_genes:R:RETSAT|RETSAT]]|-2.68|0.01|
|[[:human_genes:M:MSI2|MSI2]]|-2.61|0.01|
|[[:human_genes:V:VPS51|VPS51]]|-2.59|0.04|
|[[:human_genes:K:KMT2D|KMT2D]]|-2.59|0.01|
|[[:human_genes:H:HIST1H2AG|HIST1H2AG]]|-2.56|0.03|
|[[:human_genes:S:SLC25A37|SLC25A37]]|-2.54|0.03|
|[[:human_genes:S:SLC52A2|SLC52A2]]|-2.52|0.02|
|[[:human_genes:R:RAET1L|RAET1L]]|-2.50|0.02|
|[[:human_genes:T:TACC3|TACC3]]|-2.50|0.02|
|[[:human_genes:A:ANKRD17|ANKRD17]]|-2.49|0.03|
|[[:human_genes:Z:ZNF451|ZNF451]]|-2.48|0.03|
|[[:human_genes:D:DLGAP5|DLGAP5]]|-2.46|0.02|
|[[:human_genes:C:CYP4Z1|CYP4Z1]]|-2.45|0.02|
|[[:human_genes:K:KNTC1|KNTC1]]|-2.44|0.04|
|[[:human_genes:E:EYA2|EYA2]]|-2.43|0.04|
|[[:human_genes:E:ELMSAN1|ELMSAN1]]|-2.43|0.03|
|[[:human_genes:N:NSUN2|NSUN2]]|2.26|0.06|
|[[:human_genes:U:UBE3A|UBE3A]]|2.27|0.06|
|[[:human_genes:G:GLRX5|GLRX5]]|2.27|0.15|
|[[:human_genes:S:SP1|SP1]]|2.29|0.06|
|[[:human_genes:C:CLVS2|CLVS2]]|2.31|0.06|
|[[:human_genes:N:NDUFS5|NDUFS5]]|2.33|0.13|
|[[:human_genes:M:MS4A13|MS4A13]]|2.34|0.43|
|[[:human_genes:M:ME2|ME2]]|2.35|0.05|
|[[:human_genes:P:PRRC2C|PRRC2C]]|2.37|0.07|
|[[:human_genes:Z:ZNF737|ZNF737]]|2.41|0.06|
|[[:human_genes:T:TIMM17A|TIMM17A]]|2.44|0.06|
|[[:human_genes:F:FBXO11|FBXO11]]|2.49|0.02|
|[[:human_genes:G:GATA3|GATA3]]|2.50|0.02|
|[[:human_genes:T:TAF3|TAF3]]|2.65|0.05|
|[[:human_genes:E:EIF4A1|EIF4A1]]|2.69|0.02|
|[[:human_genes:T:TP53|TP53]]|2.71|0.02|
|[[:human_genes:P:PDSS1|PDSS1]]|2.78|0.02|
|[[:human_genes:K:KIF18B|KIF18B]]|2.80|<0.01|
|[[:human_genes:A:ALAS1|ALAS1]]|2.82|0.06|
|[[:human_genes:K:KIAA1328|KIAA1328]]|2.82|0.01|
|[[:human_genes:S:SLFN11|SLFN11]]|2.85|<0.01|
|[[:human_genes:C:COQ6|COQ6]]|3.03|0.01|
|[[:human_genes:H:HCCS|HCCS]]|3.07|0.01|
|[[:human_genes:P:PPP6R3|PPP6R3]]|3.07|<0.01|
|[[:human_genes:H:HMBS|HMBS]]|3.21|<0.01|
|[[:human_genes:A:ALAD|ALAD]]|3.26|<0.01|
|[[:human_genes:A:AHCYL1|AHCYL1]]|3.57|<0.01|
|[[:human_genes:B:BAK1|BAK1]]|3.64|<0.01|
|[[:human_genes:T:TAF5L|TAF5L]]|4.06|<0.01|
|[[:human_genes:M:MARCH5|MARCH5]]|4.09|<0.01|
</modal>


<modal id="modal_screen_similarity" size="lg" title="Correlated Screens">
^Screen^Correlation^Plot^
|[[:results:exp59|UMK57 1μM R01 exp59]]|0.105|<button type="primary" size="small" modal="1">View</button>|
|[[:results:exp529|Thimerosal 0.85μM R08 exp529]]|0.087|<button type="primary" size="small" modal="2">View</button>|
|[[:results:exp190|Vincristine 0.0005μM R04 exp190]]|0.086|<button type="primary" size="small" modal="3">View</button>|
|[[:results:exp103|Taxol 0.004μM R03 exp103]]|0.075|<button type="primary" size="small" modal="4">View</button>|
|[[:results:exp106|UM131593 0.2μM R03 exp106]]|0.071|<button type="primary" size="small" modal="5">View</button>|
|[[:results:exp416|Tubacin 1.6μM R07 exp416]]|0.069|<button type="primary" size="small" modal="6">View</button>|
|[[:results:exp525|Sulforaphane 9μM R08 exp525]]|0.069|<button type="primary" size="small" modal="7">View</button>|
|[[:results:exp84|UM0125461 0.74μM R02 exp84]]|0.067|<button type="primary" size="small" modal="8">View</button>|
|[[:results:exp60|Vinblastine 0.002μM R01 exp60]]|0.067|<button type="primary" size="small" modal="9">View</button>|
|[[:results:exp526|Sulforaphane 9μM R08 exp526 no dilution day6]]|0.065|<button type="primary" size="small" modal="10">View</button>|
|[[:results:exp107|UMK57 0.6μM R03 exp107]]|0.062|<button type="primary" size="small" modal="11">View</button>|
|[[:results:exp443|SNS-032 15μM R08 exp443]]|0.06|<button type="primary" size="small" modal="12">View</button>|
|[[:results:exp80|RO-3307 4.7μM R02 exp80]]|0.06|<button type="primary" size="small" modal="13">View</button>|
|[[:results:exp35|TRAIL 5ng/ml R00 exp35]]|0.058|<button type="primary" size="small" modal="14">View</button>|
|[[:results:exp535|Trimetrexate 0.03μM R08 exp535]]|0.058|<button type="primary" size="small" modal="15">View</button>|
|[[:results:exp531|THZ1 0.06μM R08 exp531]]|0.055|<button type="primary" size="small" modal="16">View</button>|
|[[:results:exp520|Rucaparib 6.5μM R08 exp520]]|0.055|<button type="primary" size="small" modal="17">View</button>|
|[[:results:exp36|TRAIL 50ng/ml R00 exp36]]|0.055|<button type="primary" size="small" modal="18">View</button>|
|[[:results:exp243|S-trityl-L-cysteine 0.5μM R05 exp243]]|0.055|<button type="primary" size="small" modal="19">View</button>|
|[[:results:exp147|Resveratrol 16μM R03 exp147]]|0.054|<button type="primary" size="small" modal="20">View</button>|
|[[:results:exp436|Dynasore 7μM R08 exp436]]|0.106|<button type="primary" size="small" modal="21">View</button>|
|[[:results:exp460|BML-284 0.09μM R08 exp460]]|0.106|<button type="primary" size="small" modal="22">View</button>|
|[[:results:exp312|2-Methoxyestradiol 0.55 to 1μM on day4 R07 exp312]]|0.101|<button type="primary" size="small" modal="23">View</button>|
|[[:results:exp217|Mdivi-1 15μM R05 exp217]]|0.095|<button type="primary" size="small" modal="24">View</button>|
|[[:results:exp179|Combretastatin A4 0.002 to 0.003μM day4 R04 exp179]]|0.09|<button type="primary" size="small" modal="25">View</button>|
|[[:results:exp184|Ixabepilone 0.004 to 0.005μM on day4 R04 exp184]]|0.088|<button type="primary" size="small" modal="26">View</button>|
|[[:results:exp175|3-Bromopyruvate 7μM R04 exp175]]|0.087|<button type="primary" size="small" modal="27">View</button>|
|[[:results:exp440|Aphidicolin 0.4μM R08 exp440]]|0.082|<button type="primary" size="small" modal="28">View</button>|
|[[:results:exp228|Demecolcine 0.03μM R05 exp228]]|0.082|<button type="primary" size="small" modal="29">View</button>|
|[[:results:exp78|Pterostilbene 16μM R02 exp78]]|0.079|<button type="primary" size="small" modal="30">View</button>|
|[[:results:exp227|Cryptotanshinone 12μM R05 exp227]]|0.073|<button type="primary" size="small" modal="31">View</button>|
|[[:results:exp485|GSK626616 14μM R08 exp485]]|0.073|<button type="primary" size="small" modal="32">View</button>|
|[[:results:exp357|Dorsomorphin 5μM R07 exp357]]|0.071|<button type="primary" size="small" modal="33">View</button>|
|[[:results:exp215|Colchicine 0.009μM R05 exp215]]|0.07|<button type="primary" size="small" modal="34">View</button>|
|[[:results:exp294|Nutlin-3A 1.6μM R06 exp294]]|0.07|<button type="primary" size="small" modal="35">View</button>|
|[[:results:exp450|Artemisinin 50μM R08 exp450]]|0.07|<button type="primary" size="small" modal="36">View</button>|
|[[:results:exp356|Docosahexaenoic-acid 50μM R07 exp356]]|0.069|<button type="primary" size="small" modal="37">View</button>|
|[[:results:exp500|LY2090314 0.003μM R08 exp500 no dilution day6]]|0.068|<button type="primary" size="small" modal="38">View</button>|
|[[:results:exp180|Dynasore 10μM R04 exp180]]|0.068|<button type="primary" size="small" modal="39">View</button>|
|[[:results:exp310|2-Methoxyestradiol 0.55μM R07 exp310]]|0.068|<button type="primary" size="small" modal="40">View</button>|
|[[:results:exp354|Diepoxybutane 3μM R07 exp354]]|0.067|<button type="primary" size="small" modal="41">View</button>|
|[[:results:exp512|Olaparib 4μM R08 exp512]]|0.067|<button type="primary" size="small" modal="42">View</button>|
|[[:results:exp499|LY2090314 0.003μM R08 exp499]]|0.065|<button type="primary" size="small" modal="43">View</button>|
|[[:results:exp311|2-Methoxyestradiol 0.55 to 0.75μM  on day4 R07 exp311]]|0.064|<button type="primary" size="small" modal="44">View</button>|
|[[:results:exp350|Deferoxamine 11μM R07 exp350]]|0.063|<button type="primary" size="small" modal="45">View</button>|
|[[:results:exp343|Centrinone 0.5μM R07 exp343]]|0.063|<button type="primary" size="small" modal="46">View</button>|
|[[:results:exp67|BVD-523 15μM R02 exp67]]|0.063|<button type="primary" size="small" modal="47">View</button>|
|[[:results:exp360|Genistein 15μM R07 exp360]]|0.063|<button type="primary" size="small" modal="48">View</button>|
|[[:results:exp231|Epothilone-B 0.0015μM R05 exp231]]|0.062|<button type="primary" size="small" modal="49">View</button>|
|[[:results:exp515|PU-H71 1μM R08 exp515]]|0.062|<button type="primary" size="small" modal="50">View</button>|
|[[:results:exp472|CI-1040 9.5μM R08 exp472]]|0.059|<button type="primary" size="small" modal="51">View</button>|
|[[:results:exp467|CAY10603 0.55μM R08 exp467]]|0.059|<button type="primary" size="small" modal="52">View</button>|
|[[:results:exp329|Hydroxyurea 100μM R07 exp329]]|0.058|<button type="primary" size="small" modal="53">View</button>|
|[[:results:exp321|ABT-702 5μM plus Deferoxamine 11μM R07 exp321]]|0.058|<button type="primary" size="small" modal="54">View</button>|
|[[:results:exp474|CR131-b 0.005μM R08 exp474]]|0.058|<button type="primary" size="small" modal="55">View</button>|
|[[:results:exp456|Benzoate 20000μM R08 exp456]]|0.058|<button type="primary" size="small" modal="56">View</button>|
|[[:results:exp498|Lead acetate 2000μM R08 exp498 no dilution day6]]|0.057|<button type="primary" size="small" modal="57">View</button>|
|[[:results:exp451|Atovaquone 15μM R08 exp451]]|0.055|<button type="primary" size="small" modal="58">View</button>|
|[[:results:exp116|AICAR 240μM R03 exp116]]|0.054|<button type="primary" size="small" modal="59">View</button>|
|[[:results:exp6|Bortezomib 0.005μM R00 exp6]]|0.054|<button type="primary" size="small" modal="60">View</button>|
|[[:results:exp21|MLN-4924 0.2μM R00 exp21]]|0.053|<button type="primary" size="small" modal="61">View</button>|
|[[:results:exp330|5-Azacytidine 2μM R07 exp330]]|0.052|<button type="primary" size="small" modal="62">View</button>|
|[[:results:exp290|LLY-283 2.6μM R06 exp290]]|0.051|<button type="primary" size="small" modal="63">View</button>|
|[[:results:exp503|Mitomycin-C 0.06μM R08 exp503]]|0.051|<button type="primary" size="small" modal="64">View</button>|
</modal>


<modal id="1" size="lg" title="Quercetin 20μM R08 exp517  vs  UMK57 1μM R01 exp59">
{{:chemogenomics:comparison_plots:exp517_vs_exp59.png?nolink |}}
</modal>

<modal id="2" size="lg" title="Quercetin 20μM R08 exp517  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp517_vs_exp529.png?nolink |}}
</modal>

<modal id="3" size="lg" title="Quercetin 20μM R08 exp517  vs  Vincristine 0.0005μM R04 exp190">
{{:chemogenomics:comparison_plots:exp190_vs_exp517.png?nolink |}}
</modal>

<modal id="4" size="lg" title="Quercetin 20μM R08 exp517  vs  Taxol 0.004μM R03 exp103">
{{:chemogenomics:comparison_plots:exp103_vs_exp517.png?nolink |}}
</modal>

<modal id="5" size="lg" title="Quercetin 20μM R08 exp517  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp517.png?nolink |}}
</modal>

<modal id="6" size="lg" title="Quercetin 20μM R08 exp517  vs  Tubacin 1.6μM R07 exp416">
{{:chemogenomics:comparison_plots:exp416_vs_exp517.png?nolink |}}
</modal>

<modal id="7" size="lg" title="Quercetin 20μM R08 exp517  vs  Sulforaphane 9μM R08 exp525">
{{:chemogenomics:comparison_plots:exp517_vs_exp525.png?nolink |}}
</modal>

<modal id="8" size="lg" title="Quercetin 20μM R08 exp517  vs  UM0125461 0.74μM R02 exp84">
{{:chemogenomics:comparison_plots:exp517_vs_exp84.png?nolink |}}
</modal>

<modal id="9" size="lg" title="Quercetin 20μM R08 exp517  vs  Vinblastine 0.002μM R01 exp60">
{{:chemogenomics:comparison_plots:exp517_vs_exp60.png?nolink |}}
</modal>

<modal id="10" size="lg" title="Quercetin 20μM R08 exp517  vs  Sulforaphane 9μM R08 exp526 no dilution day6">
{{:chemogenomics:comparison_plots:exp517_vs_exp526.png?nolink |}}
</modal>

<modal id="11" size="lg" title="Quercetin 20μM R08 exp517  vs  UMK57 0.6μM R03 exp107">
{{:chemogenomics:comparison_plots:exp107_vs_exp517.png?nolink |}}
</modal>

<modal id="12" size="lg" title="Quercetin 20μM R08 exp517  vs  SNS-032 15μM R08 exp443">
{{:chemogenomics:comparison_plots:exp443_vs_exp517.png?nolink |}}
</modal>

<modal id="13" size="lg" title="Quercetin 20μM R08 exp517  vs  RO-3307 4.7μM R02 exp80">
{{:chemogenomics:comparison_plots:exp517_vs_exp80.png?nolink |}}
</modal>

<modal id="14" size="lg" title="Quercetin 20μM R08 exp517  vs  TRAIL 5ng/ml R00 exp35">
{{:chemogenomics:comparison_plots:exp35_vs_exp517.png?nolink |}}
</modal>

<modal id="15" size="lg" title="Quercetin 20μM R08 exp517  vs  Trimetrexate 0.03μM R08 exp535">
{{:chemogenomics:comparison_plots:exp517_vs_exp535.png?nolink |}}
</modal>

<modal id="16" size="lg" title="Quercetin 20μM R08 exp517  vs  THZ1 0.06μM R08 exp531">
{{:chemogenomics:comparison_plots:exp517_vs_exp531.png?nolink |}}
</modal>

<modal id="17" size="lg" title="Quercetin 20μM R08 exp517  vs  Rucaparib 6.5μM R08 exp520">
{{:chemogenomics:comparison_plots:exp517_vs_exp520.png?nolink |}}
</modal>

<modal id="18" size="lg" title="Quercetin 20μM R08 exp517  vs  TRAIL 50ng/ml R00 exp36">
{{:chemogenomics:comparison_plots:exp36_vs_exp517.png?nolink |}}
</modal>

<modal id="19" size="lg" title="Quercetin 20μM R08 exp517  vs  S-trityl-L-cysteine 0.5μM R05 exp243">
{{:chemogenomics:comparison_plots:exp243_vs_exp517.png?nolink |}}
</modal>

<modal id="20" size="lg" title="Quercetin 20μM R08 exp517  vs  Resveratrol 16μM R03 exp147">
{{:chemogenomics:comparison_plots:exp147_vs_exp517.png?nolink |}}
</modal>

<modal id="21" size="lg" title="Dynasore 7μM R08 exp436  vs  Quercetin 20μM R08 exp517">
{{:chemogenomics:comparison_plots:exp436_vs_exp517.png?nolink |}}
</modal>

<modal id="22" size="lg" title="BML-284 0.09μM R08 exp460  vs  Quercetin 20μM R08 exp517">
{{:chemogenomics:comparison_plots:exp460_vs_exp517.png?nolink |}}
</modal>

<modal id="23" size="lg" title="2-Methoxyestradiol 0.55 to 1μM on day4 R07 exp312  vs  Quercetin 20μM R08 exp517">
{{:chemogenomics:comparison_plots:exp312_vs_exp517.png?nolink |}}
</modal>

<modal id="24" size="lg" title="Mdivi-1 15μM R05 exp217  vs  Quercetin 20μM R08 exp517">
{{:chemogenomics:comparison_plots:exp217_vs_exp517.png?nolink |}}
</modal>

<modal id="25" size="lg" title="Combretastatin A4 0.002 to 0.003μM day4 R04 exp179  vs  Quercetin 20μM R08 exp517">
{{:chemogenomics:comparison_plots:exp179_vs_exp517.png?nolink |}}
</modal>

<modal id="26" size="lg" title="Ixabepilone 0.004 to 0.005μM on day4 R04 exp184  vs  Quercetin 20μM R08 exp517">
{{:chemogenomics:comparison_plots:exp184_vs_exp517.png?nolink |}}
</modal>

<modal id="27" size="lg" title="3-Bromopyruvate 7μM R04 exp175  vs  Quercetin 20μM R08 exp517">
{{:chemogenomics:comparison_plots:exp175_vs_exp517.png?nolink |}}
</modal>

<modal id="28" size="lg" title="Aphidicolin 0.4μM R08 exp440  vs  Quercetin 20μM R08 exp517">
{{:chemogenomics:comparison_plots:exp440_vs_exp517.png?nolink |}}
</modal>

<modal id="29" size="lg" title="Demecolcine 0.03μM R05 exp228  vs  Quercetin 20μM R08 exp517">
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</modal>

<modal id="30" size="lg" title="Pterostilbene 16μM R02 exp78  vs  Quercetin 20μM R08 exp517">
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</modal>

<modal id="31" size="lg" title="Cryptotanshinone 12μM R05 exp227  vs  Quercetin 20μM R08 exp517">
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</modal>

<modal id="32" size="lg" title="GSK626616 14μM R08 exp485  vs  Quercetin 20μM R08 exp517">
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</modal>

<modal id="33" size="lg" title="Dorsomorphin 5μM R07 exp357  vs  Quercetin 20μM R08 exp517">
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</modal>

<modal id="34" size="lg" title="Colchicine 0.009μM R05 exp215  vs  Quercetin 20μM R08 exp517">
{{:chemogenomics:comparison_plots:exp215_vs_exp517.png?nolink |}}
</modal>

<modal id="35" size="lg" title="Nutlin-3A 1.6μM R06 exp294  vs  Quercetin 20μM R08 exp517">
{{:chemogenomics:comparison_plots:exp294_vs_exp517.png?nolink |}}
</modal>

<modal id="36" size="lg" title="Artemisinin 50μM R08 exp450  vs  Quercetin 20μM R08 exp517">
{{:chemogenomics:comparison_plots:exp450_vs_exp517.png?nolink |}}
</modal>

<modal id="37" size="lg" title="Docosahexaenoic-acid 50μM R07 exp356  vs  Quercetin 20μM R08 exp517">
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</modal>

<modal id="38" size="lg" title="LY2090314 0.003μM R08 exp500 no dilution day6  vs  Quercetin 20μM R08 exp517">
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</modal>

<modal id="39" size="lg" title="Dynasore 10μM R04 exp180  vs  Quercetin 20μM R08 exp517">
{{:chemogenomics:comparison_plots:exp180_vs_exp517.png?nolink |}}
</modal>

<modal id="40" size="lg" title="2-Methoxyestradiol 0.55μM R07 exp310  vs  Quercetin 20μM R08 exp517">
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</modal>

<modal id="41" size="lg" title="Diepoxybutane 3μM R07 exp354  vs  Quercetin 20μM R08 exp517">
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</modal>

<modal id="42" size="lg" title="Olaparib 4μM R08 exp512  vs  Quercetin 20μM R08 exp517">
{{:chemogenomics:comparison_plots:exp512_vs_exp517.png?nolink |}}
</modal>

<modal id="43" size="lg" title="LY2090314 0.003μM R08 exp499  vs  Quercetin 20μM R08 exp517">
{{:chemogenomics:comparison_plots:exp499_vs_exp517.png?nolink |}}
</modal>

<modal id="44" size="lg" title="2-Methoxyestradiol 0.55 to 0.75μM  on day4 R07 exp311  vs  Quercetin 20μM R08 exp517">
{{:chemogenomics:comparison_plots:exp311_vs_exp517.png?nolink |}}
</modal>

<modal id="45" size="lg" title="Deferoxamine 11μM R07 exp350  vs  Quercetin 20μM R08 exp517">
{{:chemogenomics:comparison_plots:exp350_vs_exp517.png?nolink |}}
</modal>

<modal id="46" size="lg" title="Centrinone 0.5μM R07 exp343  vs  Quercetin 20μM R08 exp517">
{{:chemogenomics:comparison_plots:exp343_vs_exp517.png?nolink |}}
</modal>

<modal id="47" size="lg" title="BVD-523 15μM R02 exp67  vs  Quercetin 20μM R08 exp517">
{{:chemogenomics:comparison_plots:exp517_vs_exp67.png?nolink |}}
</modal>

<modal id="48" size="lg" title="Genistein 15μM R07 exp360  vs  Quercetin 20μM R08 exp517">
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</modal>

<modal id="49" size="lg" title="Epothilone-B 0.0015μM R05 exp231  vs  Quercetin 20μM R08 exp517">
{{:chemogenomics:comparison_plots:exp231_vs_exp517.png?nolink |}}
</modal>

<modal id="50" size="lg" title="PU-H71 1μM R08 exp515  vs  Quercetin 20μM R08 exp517">
{{:chemogenomics:comparison_plots:exp515_vs_exp517.png?nolink |}}
</modal>

<modal id="51" size="lg" title="CI-1040 9.5μM R08 exp472  vs  Quercetin 20μM R08 exp517">
{{:chemogenomics:comparison_plots:exp472_vs_exp517.png?nolink |}}
</modal>

<modal id="52" size="lg" title="CAY10603 0.55μM R08 exp467  vs  Quercetin 20μM R08 exp517">
{{:chemogenomics:comparison_plots:exp467_vs_exp517.png?nolink |}}
</modal>

<modal id="53" size="lg" title="Hydroxyurea 100μM R07 exp329  vs  Quercetin 20μM R08 exp517">
{{:chemogenomics:comparison_plots:exp329_vs_exp517.png?nolink |}}
</modal>

<modal id="54" size="lg" title="ABT-702 5μM plus Deferoxamine 11μM R07 exp321  vs  Quercetin 20μM R08 exp517">
{{:chemogenomics:comparison_plots:exp321_vs_exp517.png?nolink |}}
</modal>

<modal id="55" size="lg" title="CR131-b 0.005μM R08 exp474  vs  Quercetin 20μM R08 exp517">
{{:chemogenomics:comparison_plots:exp474_vs_exp517.png?nolink |}}
</modal>

<modal id="56" size="lg" title="Benzoate 20000μM R08 exp456  vs  Quercetin 20μM R08 exp517">
{{:chemogenomics:comparison_plots:exp456_vs_exp517.png?nolink |}}
</modal>

<modal id="57" size="lg" title="Lead acetate 2000μM R08 exp498 no dilution day6  vs  Quercetin 20μM R08 exp517">
{{:chemogenomics:comparison_plots:exp498_vs_exp517.png?nolink |}}
</modal>

<modal id="58" size="lg" title="Atovaquone 15μM R08 exp451  vs  Quercetin 20μM R08 exp517">
{{:chemogenomics:comparison_plots:exp451_vs_exp517.png?nolink |}}
</modal>

<modal id="59" size="lg" title="AICAR 240μM R03 exp116  vs  Quercetin 20μM R08 exp517">
{{:chemogenomics:comparison_plots:exp116_vs_exp517.png?nolink |}}
</modal>

<modal id="60" size="lg" title="Bortezomib 0.005μM R00 exp6  vs  Quercetin 20μM R08 exp517">
{{:chemogenomics:comparison_plots:exp517_vs_exp6.png?nolink |}}
</modal>

<modal id="61" size="lg" title="MLN-4924 0.2μM R00 exp21  vs  Quercetin 20μM R08 exp517">
{{:chemogenomics:comparison_plots:exp21_vs_exp517.png?nolink |}}
</modal>

<modal id="62" size="lg" title="5-Azacytidine 2μM R07 exp330  vs  Quercetin 20μM R08 exp517">
{{:chemogenomics:comparison_plots:exp330_vs_exp517.png?nolink |}}
</modal>

<modal id="63" size="lg" title="LLY-283 2.6μM R06 exp290  vs  Quercetin 20μM R08 exp517">
{{:chemogenomics:comparison_plots:exp290_vs_exp517.png?nolink |}}
</modal>

<modal id="64" size="lg" title="Mitomycin-C 0.06μM R08 exp503  vs  Quercetin 20μM R08 exp517">
{{:chemogenomics:comparison_plots:exp503_vs_exp517.png?nolink |}}
</modal>



<modal id="modal_go_sensitive" size="lg" title="Top 30 sensitive GO terms">
^GO Term^Fold Change^Genes^
|GATOR1 complex|571.34|NPRL3,NPRL2|
</modal>
<modal id="modal_go_resistant" size="lg" title="Top 30 resistant GO terms">
^GO Term^Fold Change^Genes^
|protoporphyrinogen IX biosynthetic process|207.11|ALAD,HMBS,ALAS1|
|protoporphyrinogen IX metabolic process|165.69|ALAD,HMBS,ALAS1|
|release of cytochrome c from mitochondria|78.90|BAK1,TP53,PMAIP1|
|positive regulation of release of cytochrome c from mitochondria|69.04|BAK1,TP53,PMAIP1|
|heme biosynthetic process|66.28|ALAD,HMBS,ALAS1|
|tetrapyrrole biosynthetic process|59.18|ALAD,HMBS,ALAS1|
|porphyrin-containing compound biosynthetic process|59.18|ALAD,HMBS,ALAS1|
|positive regulation of mitochondrion organization|30.26|MARCHF5,BAK1,TP53,PMAIP1|
|mitochondrial membrane|7.83|MARCHF5,BAK1,HCCS,COQ6,ALAS1,TIMM17A,NDUFS5,PMAIP1,SLC25A51,YME1L1|
|organelle inner membrane|7.58|HCCS,COQ6,ALAS1,TIMM17A,NDUFS5,SLC25A51,YME1L1|
|mitochondrial envelope|7.35|MARCHF5,BAK1,HCCS,COQ6,ALAS1,TIMM17A,NDUFS5,PMAIP1,SLC25A51,YME1L1|
</modal>