====== Thimerosal 0.85μM R08 exp529 ======
==== Mechanism of Action ====
Organomercury compound, antiseptic and antifungal, approved preservative in vaccines
  * **<color #00a2e8>Class / Subclass 1:</color>** Infectious Disease / Antifungal




==== Technical Notes ====
<accordion collapsed='true'>
<panel title='Compound References' collapsed='true'>
    * **<color #00a2e8>PubChem Name:</color>** %%Thimerosal%%
    * **<color #00a2e8>Synonyms:</color>** N/A
    * **<color #00a2e8>CAS #:</color>** 54-64-8
    * **<color #00a2e8>PubChem CID:</color>** [[https://pubchem.ncbi.nlm.nih.gov/compound/16684434|16684434]]
    * **<color #00a2e8>IUPAC:</color>** %%sodium;(2-carboxylatophenyl)sulfanyl-ethylmercury%%
    * **<color #00a2e8>INCHI Name:</color>** InChI=1S/C7H6O2S.C2H5.Hg.Na/c8-7(9)5-3-1-2-4-6(5)10;1-2;;/h1-4,10H,(H,8,9);1H2,2H3;;/q;;2*+1/p-2
    * **<color #00a2e8>INCHI Key:</color>** RTKIYNMVFMVABJ-UHFFFAOYSA-L
    * **<color #00a2e8>Molecular Weight:</color>** 404.82
    * **<color #00a2e8>Canonical SMILES:</color>** CC[Hg]SC1=CC=CC=C1C(=O)[O-].[Na+]
    * **<color #00a2e8>Isomeric SMILES:</color>** N/A
    * **<color #00a2e8>Molecular Formula:</color>** VLALYNQHNP GASAAPCCVP QALEPLPIVY YVGRKPKVEQ LSNMIVRSCK CS
{{:chemogenomics:structures:chem-0333.svg?nolink}}
</panel>


<panel title='Compound Supplier' collapsed='true'>
    * **<color #00a2e8>Supplier Name:</color>** Med Chem Express
    * **<color #00a2e8>Catalog #:</color>** HY-19588
    * **<color #00a2e8>Lot #:</color>** 27402
</panel>


<panel title='Compound Characterization' collapsed='true'>
    * **<color #00a2e8>XRPD:</color>** Expected C9H9HgNaO2S; found C9H9HgNaO2S
</panel>


<panel title='Dose Response Curve' collapsed='true'>
    * **<color #00a2e8>Platform ID:</color>** Thimerosal
    * **<color #00a2e8>Min:</color>** -8.7605; **<color #00a2e8>Max:</color>** 99.8675
{{:chemogenomics:dose_response:dr_586.png?nolink&500 |}}
\\ 
\\ 
\\ 
\\ 
|< 300px 100px 200px >|
^ IC   ^ Concentration (µM) ^
| IC10  |0.6073    |
| IC20  |0.7434    |
| IC30  |0.8504    |
| IC40  |0.9495    |
| IC50  |1.0500    |
| IC60  |1.1620    |
| IC70  |1.2980    |
| IC80  |1.4840    |
| IC90  |1.8170    |
\\ 
</panel>
</accordion>
==== Screen Summary ====
    * **<color #00a2e8>Round</color>**: 08
    * **<color #00a2e8>Dose</color>**: 850nM
    * **<color #00a2e8>Days of incubation</color>**: 8
    * **<color #00a2e8>Doublings</color>**: 1.6
    * **<color #00a2e8>Numbers of reads</color>**: 15847503


==== Screen Results ====


^Sensitive/Resistant hits (FDR<0.05)^CRANKS^Score Plot^Top 30 Genes^Screen Similarity^Top 30 Sensitive GO terms^Top 30 Resistant GO terms^
|20/99|<color #e85500>[[https://files.tyerslab.com/files/public/chemogenomics/cranks/Thimerosal_0.85uM_Round-8_exp529.txt|Scores]]</color>|<button type="primary" size="sm" modal="ScorePlot">View</button>|<button type="primary" size="sm" modal="modal_hits">View</button>|<button type="primary" size="sm" modal="modal_screen_similarity">View</button>|<button type="primary" size="sm" modal="modal_go_sensitive">View</button>|<button type="primary" size="sm" modal="modal_go_resistant">View</button>|
<modal id='ScorePlot' size='lg' title='Thimerosal 0.85μM R08 exp529'>
{{:chemogenomics:cranks_plots:exp529.png?nolink}}
</modal>


<modal id="modal_hits" size="sm" title="Top 30 S/R Genes">
^Gene^CRANKS Score^FDR^
|[[:human_genes:A:ABCC1|ABCC1]]|-5.26|<0.01|
|[[:human_genes:M:MSI2|MSI2]]|-3.83|<0.01|
|[[:human_genes:W:WDR26|WDR26]]|-3.63|<0.01|
|[[:human_genes:G:GSS|GSS]]|-3.60|<0.01|
|[[:human_genes:S:STMN1|STMN1]]|-3.47|<0.01|
|[[:human_genes:N:NPRL3|NPRL3]]|-3.36|<0.01|
|[[:human_genes:G:GCLM|GCLM]]|-3.32|<0.01|
|[[:human_genes:N:NGLY1|NGLY1]]|-3.30|<0.01|
|[[:human_genes:G:GCLC|GCLC]]|-3.25|<0.01|
|[[:human_genes:X:XPR1|XPR1]]|-3.18|<0.01|
|[[:human_genes:S:SSH2|SSH2]]|-3.14|<0.01|
|[[:human_genes:L:LRP8|LRP8]]|-2.91|<0.01|
|[[:human_genes:C:CCT2|CCT2]]|-2.86|0.25|
|[[:human_genes:Y:YPEL5|YPEL5]]|-2.80|<0.01|
|[[:human_genes:K:KIF15|KIF15]]|-2.75|<0.01|
|[[:human_genes:D:DDI2|DDI2]]|-2.60|0.01|
|[[:human_genes:S:SLC7A11|SLC7A11]]|-2.58|0.02|
|[[:human_genes:M:MDM2|MDM2]]|-2.57|0.07|
|[[:human_genes:T:TNPO3|TNPO3]]|-2.55|0.19|
|[[:human_genes:O:OTUB1|OTUB1]]|-2.54|0.04|
|[[:human_genes:F:FAM111B|FAM111B]]|-2.52|0.02|
|[[:human_genes:C:CPSF2|CPSF2]]|-2.44|0.20|
|[[:human_genes:T:TUBA1B|TUBA1B]]|-2.43|0.06|
|[[:human_genes:G:GPX4|GPX4]]|-2.40|0.04|
|[[:human_genes:M:MTMR4|MTMR4]]|-2.36|0.05|
|[[:human_genes:K:KIAA0020|KIAA0020]]|-2.31|0.15|
|[[:human_genes:R:RANBP1|RANBP1]]|-2.29|0.06|
|[[:human_genes:H:HNRNPK|HNRNPK]]|-2.26|0.17|
|[[:human_genes:G:GAK|GAK]]|-2.25|0.07|
|[[:human_genes:C:CNOT8|CNOT8]]|-2.25|0.07|
|[[:human_genes:G:GFM1|GFM1]]|2.73|0.01|
|[[:human_genes:L:LARS2|LARS2]]|2.75|<0.01|
|[[:human_genes:H:HMGXB3|HMGXB3]]|2.77|<0.01|
|[[:human_genes:B:BACH2|BACH2]]|2.77|<0.01|
|[[:human_genes:K:KMT2D|KMT2D]]|2.77|<0.01|
|[[:human_genes:N:NARS2|NARS2]]|2.77|<0.01|
|[[:human_genes:M:MRPS25|MRPS25]]|2.81|<0.01|
|[[:human_genes:P:PARS2|PARS2]]|2.82|<0.01|
|[[:human_genes:K:KLF16|KLF16]]|2.83|<0.01|
|[[:human_genes:S:SELRC1|SELRC1]]|2.84|<0.01|
|[[:human_genes:C:CARS2|CARS2]]|2.84|<0.01|
|[[:human_genes:M:MRPL53|MRPL53]]|2.86|<0.01|
|[[:human_genes:R:RNASEH1|RNASEH1]]|2.87|<0.01|
|[[:human_genes:E:EIF4A1|EIF4A1]]|2.91|<0.01|
|[[:human_genes:U:UBQLN1|UBQLN1]]|3.07|0.00|
|[[:human_genes:L:LPCAT3|LPCAT3]]|3.09|0.00|
|[[:human_genes:B:BAK1|BAK1]]|3.10|0.00|
|[[:human_genes:S:SRM|SRM]]|3.11|0.00|
|[[:human_genes:E:EARS2|EARS2]]|3.13|<0.01|
|[[:human_genes:D:DARS2|DARS2]]|3.18|0.01|
|[[:human_genes:Y:YARS2|YARS2]]|3.20|<0.01|
|[[:human_genes:T:TARS2|TARS2]]|3.24|<0.01|
|[[:human_genes:W:WBSCR16|WBSCR16]]|3.25|0.03|
|[[:human_genes:P:PRRC2A|PRRC2A]]|3.28|0.00|
|[[:human_genes:E:EIF3H|EIF3H]]|3.34|0.00|
|[[:human_genes:A:ACSL4|ACSL4]]|3.47|0.00|
|[[:human_genes:R:RBM7|RBM7]]|3.66|0.00|
|[[:human_genes:T:TAZ|TAZ]]|3.74|<0.01|
|[[:human_genes:S:SEC62|SEC62]]|3.96|0.00|
|[[:human_genes:I:IKZF1|IKZF1]]|4.11|0.00|
</modal>


<modal id="modal_screen_similarity" size="lg" title="Correlated Screens">
^Screen^Correlation^Plot^
|[[:results:exp84|UM0125461 0.74μM R02 exp84]]|0.12|<button type="primary" size="small" modal="1">View</button>|
|[[:results:exp492|iCRT14 30μM R08 exp492]]|0.088|<button type="primary" size="small" modal="2">View</button>|
|[[:results:exp416|Tubacin 1.6μM R07 exp416]]|0.076|<button type="primary" size="small" modal="3">View</button>|
|[[:results:exp535|Trimetrexate 0.03μM R08 exp535]]|0.058|<button type="primary" size="small" modal="4">View</button>|
|[[:results:exp59|UMK57 1μM R01 exp59]]|0.053|<button type="primary" size="small" modal="5">View</button>|
|[[:results:exp106|UM131593 0.2μM R03 exp106]]|0.052|<button type="primary" size="small" modal="6">View</button>|
|[[:results:exp329|Hydroxyurea 100μM R07 exp329]]|0.171|<button type="primary" size="small" modal="7">View</button>|
|[[:results:exp515|PU-H71 1μM R08 exp515]]|0.121|<button type="primary" size="small" modal="8">View</button>|
|[[:results:exp440|Aphidicolin 0.4μM R08 exp440]]|0.112|<button type="primary" size="small" modal="9">View</button>|
|[[:results:exp25|Oligomycin-A 2μM R00 exp25]]|0.1|<button type="primary" size="small" modal="10">View</button>|
|[[:results:exp290|LLY-283 2.6μM R06 exp290]]|0.096|<button type="primary" size="small" modal="11">View</button>|
|[[:results:exp513|ONC212 0.15μM R08 exp513]]|0.094|<button type="primary" size="small" modal="12">View</button>|
|[[:results:exp441|GSK-J4 1.5μM R08 exp441]]|0.093|<button type="primary" size="small" modal="13">View</button>|
|[[:results:exp450|Artemisinin 50μM R08 exp450]]|0.091|<button type="primary" size="small" modal="14">View</button>|
|[[:results:exp472|CI-1040 9.5μM R08 exp472]]|0.089|<button type="primary" size="small" modal="15">View</button>|
|[[:results:exp527|Tanespimycin 14μM R08 exp527]]|0.089|<button type="primary" size="small" modal="16">View</button>|
|[[:results:exp517|Quercetin 20μM R08 exp517]]|0.087|<button type="primary" size="small" modal="17">View</button>|
|[[:results:exp512|Olaparib 4μM R08 exp512]]|0.086|<button type="primary" size="small" modal="18">View</button>|
|[[:results:exp264|Arsenate 40μM R06 exp264]]|0.086|<button type="primary" size="small" modal="19">View</button>|
|[[:results:exp532|TIC10 10μM R08 exp532]]|0.085|<button type="primary" size="small" modal="20">View</button>|
|[[:results:exp489|Hippuristanol 0.12μM R08 exp489 no dilution day6]]|0.084|<button type="primary" size="small" modal="21">View</button>|
|[[:results:exp474|CR131-b 0.005μM R08 exp474]]|0.084|<button type="primary" size="small" modal="22">View</button>|
|[[:results:exp78|Pterostilbene 16μM R02 exp78]]|0.083|<button type="primary" size="small" modal="23">View</button>|
|[[:results:exp488|Hippuristanol 0.12μM R08 exp488]]|0.083|<button type="primary" size="small" modal="24">View</button>|
|[[:results:exp485|GSK626616 14μM R08 exp485]]|0.08|<button type="primary" size="small" modal="25">View</button>|
|[[:results:exp468|CB-5083 0.4μM R08 exp468]]|0.08|<button type="primary" size="small" modal="26">View</button>|
|[[:results:exp456|Benzoate 20000μM R08 exp456]]|0.072|<button type="primary" size="small" modal="27">View</button>|
|[[:results:exp503|Mitomycin-C 0.06μM R08 exp503]]|0.071|<button type="primary" size="small" modal="28">View</button>|
|[[:results:exp525|Sulforaphane 9μM R08 exp525]]|0.071|<button type="primary" size="small" modal="29">View</button>|
|[[:results:exp435|JQ1 0.8μM R08 exp435]]|0.07|<button type="primary" size="small" modal="30">View</button>|
|[[:results:exp360|Genistein 15μM R07 exp360]]|0.069|<button type="primary" size="small" modal="31">View</button>|
|[[:results:exp451|Atovaquone 15μM R08 exp451]]|0.069|<button type="primary" size="small" modal="32">View</button>|
|[[:results:exp211|AICAR 240μM R05 exp211]]|0.068|<button type="primary" size="small" modal="33">View</button>|
|[[:results:exp356|Docosahexaenoic-acid 50μM R07 exp356]]|0.067|<button type="primary" size="small" modal="34">View</button>|
|[[:results:exp439|QNZ 0.01μM R08 exp439]]|0.066|<button type="primary" size="small" modal="35">View</button>|
|[[:results:exp524|Staurosporine 0.02μM R08 exp524]]|0.065|<button type="primary" size="small" modal="36">View</button>|
|[[:results:exp445|∆-9-Tetrahydrocannabinol 30μM R08 exp445]]|0.063|<button type="primary" size="small" modal="37">View</button>|
|[[:results:exp478|Doxorubicin 0.02μM R08 exp478]]|0.063|<button type="primary" size="small" modal="38">View</button>|
|[[:results:exp66|BI-D1870 3.15μM R02 exp66]]|0.062|<button type="primary" size="small" modal="39">View</button>|
|[[:results:exp459|Bleomycin 5μM R08 exp459]]|0.061|<button type="primary" size="small" modal="40">View</button>|
|[[:results:exp447|Amiloride 100μM R08 exp447]]|0.06|<button type="primary" size="small" modal="41">View</button>|
|[[:results:exp443|SNS-032 15μM R08 exp443]]|0.06|<button type="primary" size="small" modal="42">View</button>|
|[[:results:exp526|Sulforaphane 9μM R08 exp526 no dilution day6]]|0.06|<button type="primary" size="small" modal="43">View</button>|
|[[:results:exp288|HMS-I2 10μM R06 exp288]]|0.059|<button type="primary" size="small" modal="44">View</button>|
|[[:results:exp350|Deferoxamine 11μM R07 exp350]]|0.059|<button type="primary" size="small" modal="45">View</button>|
|[[:results:exp539|42°C R08 exp539]]|0.056|<button type="primary" size="small" modal="46">View</button>|
|[[:results:exp502|Milciclib 2μM R08 exp502]]|0.056|<button type="primary" size="small" modal="47">View</button>|
|[[:results:exp175|3-Bromopyruvate 7μM R04 exp175]]|0.052|<button type="primary" size="small" modal="48">View</button>|
|[[:results:exp449|Arsenic trioxide 60μM R08 exp449]]|0.052|<button type="primary" size="small" modal="49">View</button>|
|[[:results:exp531|THZ1 0.06μM R08 exp531]]|0.052|<button type="primary" size="small" modal="50">View</button>|
|[[:results:exp116|AICAR 240μM R03 exp116]]|0.052|<button type="primary" size="small" modal="51">View</button>|
|[[:results:exp357|Dorsomorphin 5μM R07 exp357]]|0.051|<button type="primary" size="small" modal="52">View</button>|
|[[:results:exp48|Mubritinib 0.2μM R01 exp48]]|0.051|<button type="primary" size="small" modal="53">View</button>|
</modal>


<modal id="1" size="lg" title="Thimerosal 0.85μM R08 exp529  vs  UM0125461 0.74μM R02 exp84">
{{:chemogenomics:comparison_plots:exp529_vs_exp84.png?nolink |}}
</modal>

<modal id="2" size="lg" title="Thimerosal 0.85μM R08 exp529  vs  iCRT14 30μM R08 exp492">
{{:chemogenomics:comparison_plots:exp492_vs_exp529.png?nolink |}}
</modal>

<modal id="3" size="lg" title="Thimerosal 0.85μM R08 exp529  vs  Tubacin 1.6μM R07 exp416">
{{:chemogenomics:comparison_plots:exp416_vs_exp529.png?nolink |}}
</modal>

<modal id="4" size="lg" title="Thimerosal 0.85μM R08 exp529  vs  Trimetrexate 0.03μM R08 exp535">
{{:chemogenomics:comparison_plots:exp529_vs_exp535.png?nolink |}}
</modal>

<modal id="5" size="lg" title="Thimerosal 0.85μM R08 exp529  vs  UMK57 1μM R01 exp59">
{{:chemogenomics:comparison_plots:exp529_vs_exp59.png?nolink |}}
</modal>

<modal id="6" size="lg" title="Thimerosal 0.85μM R08 exp529  vs  UM131593 0.2μM R03 exp106">
{{:chemogenomics:comparison_plots:exp106_vs_exp529.png?nolink |}}
</modal>

<modal id="7" size="lg" title="Hydroxyurea 100μM R07 exp329  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp329_vs_exp529.png?nolink |}}
</modal>

<modal id="8" size="lg" title="PU-H71 1μM R08 exp515  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp515_vs_exp529.png?nolink |}}
</modal>

<modal id="9" size="lg" title="Aphidicolin 0.4μM R08 exp440  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp440_vs_exp529.png?nolink |}}
</modal>

<modal id="10" size="lg" title="Oligomycin-A 2μM R00 exp25  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp25_vs_exp529.png?nolink |}}
</modal>

<modal id="11" size="lg" title="LLY-283 2.6μM R06 exp290  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp290_vs_exp529.png?nolink |}}
</modal>

<modal id="12" size="lg" title="ONC212 0.15μM R08 exp513  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp513_vs_exp529.png?nolink |}}
</modal>

<modal id="13" size="lg" title="GSK-J4 1.5μM R08 exp441  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp441_vs_exp529.png?nolink |}}
</modal>

<modal id="14" size="lg" title="Artemisinin 50μM R08 exp450  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp450_vs_exp529.png?nolink |}}
</modal>

<modal id="15" size="lg" title="CI-1040 9.5μM R08 exp472  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp472_vs_exp529.png?nolink |}}
</modal>

<modal id="16" size="lg" title="Tanespimycin 14μM R08 exp527  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp527_vs_exp529.png?nolink |}}
</modal>

<modal id="17" size="lg" title="Quercetin 20μM R08 exp517  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp517_vs_exp529.png?nolink |}}
</modal>

<modal id="18" size="lg" title="Olaparib 4μM R08 exp512  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp512_vs_exp529.png?nolink |}}
</modal>

<modal id="19" size="lg" title="Arsenate 40μM R06 exp264  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp264_vs_exp529.png?nolink |}}
</modal>

<modal id="20" size="lg" title="TIC10 10μM R08 exp532  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp529_vs_exp532.png?nolink |}}
</modal>

<modal id="21" size="lg" title="Hippuristanol 0.12μM R08 exp489 no dilution day6  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp489_vs_exp529.png?nolink |}}
</modal>

<modal id="22" size="lg" title="CR131-b 0.005μM R08 exp474  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp474_vs_exp529.png?nolink |}}
</modal>

<modal id="23" size="lg" title="Pterostilbene 16μM R02 exp78  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp529_vs_exp78.png?nolink |}}
</modal>

<modal id="24" size="lg" title="Hippuristanol 0.12μM R08 exp488  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp488_vs_exp529.png?nolink |}}
</modal>

<modal id="25" size="lg" title="GSK626616 14μM R08 exp485  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp485_vs_exp529.png?nolink |}}
</modal>

<modal id="26" size="lg" title="CB-5083 0.4μM R08 exp468  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp468_vs_exp529.png?nolink |}}
</modal>

<modal id="27" size="lg" title="Benzoate 20000μM R08 exp456  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp456_vs_exp529.png?nolink |}}
</modal>

<modal id="28" size="lg" title="Mitomycin-C 0.06μM R08 exp503  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp503_vs_exp529.png?nolink |}}
</modal>

<modal id="29" size="lg" title="Sulforaphane 9μM R08 exp525  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp525_vs_exp529.png?nolink |}}
</modal>

<modal id="30" size="lg" title="JQ1 0.8μM R08 exp435  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp435_vs_exp529.png?nolink |}}
</modal>

<modal id="31" size="lg" title="Genistein 15μM R07 exp360  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp360_vs_exp529.png?nolink |}}
</modal>

<modal id="32" size="lg" title="Atovaquone 15μM R08 exp451  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp451_vs_exp529.png?nolink |}}
</modal>

<modal id="33" size="lg" title="AICAR 240μM R05 exp211  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp211_vs_exp529.png?nolink |}}
</modal>

<modal id="34" size="lg" title="Docosahexaenoic-acid 50μM R07 exp356  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp356_vs_exp529.png?nolink |}}
</modal>

<modal id="35" size="lg" title="QNZ 0.01μM R08 exp439  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp439_vs_exp529.png?nolink |}}
</modal>

<modal id="36" size="lg" title="Staurosporine 0.02μM R08 exp524  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp524_vs_exp529.png?nolink |}}
</modal>

<modal id="37" size="lg" title="∆-9-Tetrahydrocannabinol 30μM R08 exp445  vs  Thimerosal 0.85μM R08 exp529">
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</modal>

<modal id="38" size="lg" title="Doxorubicin 0.02μM R08 exp478  vs  Thimerosal 0.85μM R08 exp529">
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</modal>

<modal id="39" size="lg" title="BI-D1870 3.15μM R02 exp66  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp529_vs_exp66.png?nolink |}}
</modal>

<modal id="40" size="lg" title="Bleomycin 5μM R08 exp459  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp459_vs_exp529.png?nolink |}}
</modal>

<modal id="41" size="lg" title="Amiloride 100μM R08 exp447  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp447_vs_exp529.png?nolink |}}
</modal>

<modal id="42" size="lg" title="SNS-032 15μM R08 exp443  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp443_vs_exp529.png?nolink |}}
</modal>

<modal id="43" size="lg" title="Sulforaphane 9μM R08 exp526 no dilution day6  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp526_vs_exp529.png?nolink |}}
</modal>

<modal id="44" size="lg" title="HMS-I2 10μM R06 exp288  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp288_vs_exp529.png?nolink |}}
</modal>

<modal id="45" size="lg" title="Deferoxamine 11μM R07 exp350  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp350_vs_exp529.png?nolink |}}
</modal>

<modal id="46" size="lg" title="42°C R08 exp539  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp529_vs_exp539.png?nolink |}}
</modal>

<modal id="47" size="lg" title="Milciclib 2μM R08 exp502  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp502_vs_exp529.png?nolink |}}
</modal>

<modal id="48" size="lg" title="3-Bromopyruvate 7μM R04 exp175  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp175_vs_exp529.png?nolink |}}
</modal>

<modal id="49" size="lg" title="Arsenic trioxide 60μM R08 exp449  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp449_vs_exp529.png?nolink |}}
</modal>

<modal id="50" size="lg" title="THZ1 0.06μM R08 exp531  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp529_vs_exp531.png?nolink |}}
</modal>

<modal id="51" size="lg" title="AICAR 240μM R03 exp116  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp116_vs_exp529.png?nolink |}}
</modal>

<modal id="52" size="lg" title="Dorsomorphin 5μM R07 exp357  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp357_vs_exp529.png?nolink |}}
</modal>

<modal id="53" size="lg" title="Mubritinib 0.2μM R01 exp48  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp48_vs_exp529.png?nolink |}}
</modal>



<modal id="modal_go_sensitive" size="lg" title="Top 30 sensitive GO terms">
^GO Term^Fold Change^Genes^
|nonribosomal peptide biosynthetic process|122.43|GSS,GCLM,GCLC|
|acid-amino acid ligase activity|81.62|GSS,GCLM,GCLC|
|glutathione metabolic process|54.94|GSS,GCLM,GCLC,SLC7A11,GPX4|
|response to oxidative stress|11.39|ABCC1,GSS,GCLM,GCLC,SLC7A11,MDM2,GPX4|
</modal>
<modal id="modal_go_resistant" size="lg" title="Top 30 resistant GO terms">
^GO Term^Fold Change^Genes^
|tRNA aminoacylation for mitochondrial protein translation|315.60|TARS2,YARS2,DARS2,EARS2|
|tRNA aminoacylation for protein translation|116.27|TARS2,YARS2,DARS2,EARS2,CARS2,PARS2,NARS2,LARS2|
|aminoacyl-tRNA ligase activity|116.27|TARS2,YARS2,DARS2,EARS2,CARS2,PARS2,NARS2,LARS2|
|ligase activity, forming carbon-oxygen bonds|116.27|TARS2,YARS2,DARS2,EARS2,CARS2,PARS2,NARS2,LARS2|
|tRNA aminoacylation|107.77|TARS2,YARS2,DARS2,EARS2,CARS2,PARS2,NARS2,LARS2|
|amino acid activation|105.20|TARS2,YARS2,DARS2,EARS2,CARS2,PARS2,NARS2,LARS2|
|mitochondrial RNA metabolic process|64.22|TARS2,YARS2,DARS2,EARS2,LRPPRC|
|mitochondrial translation|46.46|TARS2,YARS2,DARS2,EARS2,MRPL53,MRPS25,LARS2,MRPS27,GFM1|
|mitochondrial gene expression|35.76|TARS2,YARS2,DARS2,EARS2,MRPL53,MRPS25,LARS2,MRPS27,GFM1|
|catalytic activity, acting on a tRNA|35.35|TARS2,YARS2,DARS2,EARS2,CARS2,PARS2,NARS2,LARS2|
|ligase activity|31.66|ACSL4,TARS2,YARS2,DARS2,EARS2,CARS2,PARS2,NARS2,LARS2|
|tRNA metabolic process|23.75|TARS2,YARS2,DARS2,EARS2,CARS2,PARS2,NARS2,LARS2|
|translation|21.66|EIF3H,TARS2,YARS2,DARS2,EARS2,EIF4A1,MRPL53,CARS2,PARS2,MRPS25,NARS2,LARS2,MRPS27,GFM1|
|peptide biosynthetic process|20.24|EIF3H,TARS2,YARS2,DARS2,EARS2,EIF4A1,MRPL53,CARS2,PARS2,MRPS25,NARS2,LARS2,MRPS27,GFM1|
|amide biosynthetic process|16.47|ACSL4,EIF3H,TARS2,YARS2,DARS2,EARS2,EIF4A1,MRPL53,CARS2,PARS2,MRPS25,NARS2,LARS2,MRPS27,GFM1|
|mitochondrial matrix|16.31|TARS2,YARS2,DARS2,EARS2,MRPL53,CARS2,PARS2,MRPS25,NARS2,LARS2,MRPS27,ALAS1,GFM1,LRPPRC|
|peptide metabolic process|16.31|EIF3H,TARS2,YARS2,DARS2,EARS2,EIF4A1,MRPL53,CARS2,PARS2,MRPS25,NARS2,LARS2,MRPS27,GFM1|
|catalytic activity, acting on RNA|14.42|TARS2,YARS2,DARS2,EARS2,EIF4A1,RNASEH1,CARS2,PARS2,NARS2,LARS2|
|amide metabolic process|10.94|ACSL4,EIF3H,TARS2,YARS2,DARS2,EARS2,EIF4A1,MRPL53,CARS2,PARS2,MRPS25,NARS2,LARS2,MRPS27,GFM1|
</modal>