====== UM0129480 7μM R02 exp85 ======
==== Mechanism of Action ====
Unknown
  * **<color #00a2e8>Class / Subclass 1:</color>** Uncharacterized Mechanism / Chemical Screen Hit




==== Technical Notes ====
<accordion collapsed='true'>
<panel title='Compound References' collapsed='true'>
    * **<color #00a2e8>PubChem Name:</color>** %%N/A%%
    * **<color #00a2e8>Synonyms:</color>** N/A
    * **<color #00a2e8>CAS #:</color>** N/A
    * **<color #00a2e8>PubChem CID:</color>** N/A
    * **<color #00a2e8>IUPAC:</color>** %%N/A%%
    * **<color #00a2e8>INCHI Name:</color>** N/A
    * **<color #00a2e8>INCHI Key:</color>** N/A
    * **<color #00a2e8>Molecular Weight:</color>** 565.43
    * **<color #00a2e8>Canonical SMILES:</color>** N/A
    * **<color #00a2e8>Isomeric SMILES:</color>** N/A
    * **<color #00a2e8>Molecular Formula:</color>** C27H21N2O2F3SCl2
{{:chemogenomics:structures:chem-0061.svg?nolink}}
</panel>


<panel title='Compound Supplier' collapsed='true'>
    * **<color #00a2e8>Supplier Name:</color>** In house - University of Montreal - Chemistry Platform
    * **<color #00a2e8>Catalog #:</color>** N/A
    * **<color #00a2e8>Lot #:</color>** IRIC-004 / 2119-072-1 Rico Lavo / Batch #01
</panel>


<panel title='Compound Characterization' collapsed='true'>
    * **<color #00a2e8>HRMS (ESI-TOF) m/z:</color>** (M+H)+ Calcd for C27H21Cl2F3N2O2S 565.07257; found 565.07328
</panel>


<panel title='Dose Response Curve' collapsed='true'>
    * **<color #00a2e8>Platform ID:</color>** UM129480
    * **<color #00a2e8>Min:</color>** -12.7498; **<color #00a2e8>Max:</color>** 77.5794
{{:chemogenomics:dose_response:dr_26.png?nolink&500 |}}
\\ 
\\ 
\\ 
\\ 
|< 300px 100px 200px >|
^ IC   ^ Concentration (µM) ^
| IC10  |N/A    |
| IC20  |4.6558    |
| IC30  |5.4831    |
| IC40  |6.2699    |
| IC50  |7.0908    |
| IC60  |N/A    |
| IC70  |N/A    |
| IC80  |N/A    |
| IC90  |N/A    |
\\ 
</panel>
</accordion>
==== Screen Summary ====
    * **<color #00a2e8>Round</color>**: 02
    * **<color #00a2e8>Dose</color>**: 7µM
    * **<color #00a2e8>Days of incubation</color>**: 8
    * **<color #00a2e8>Doublings</color>**: 1.5
    * **<color #00a2e8>Numbers of reads</color>**: 13412153


==== Screen Results ====


^Sensitive/Resistant hits (FDR<0.05)^CRANKS^Score Plot^Top 30 Genes^Screen Similarity^Top 30 Sensitive GO terms^Top 30 Resistant GO terms^
|15/42|<color #e85500>[[https://files.tyerslab.com/files/public/chemogenomics/cranks/UM0129480_7uM_Round-2_exp85.txt|Scores]]</color>|<button type="primary" size="sm" modal="ScorePlot">View</button>|<button type="primary" size="sm" modal="modal_hits">View</button>|<button type="primary" size="sm" modal="modal_screen_similarity">View</button>|<button type="primary" size="sm" modal="modal_go_sensitive">View</button>|<button type="primary" size="sm" modal="modal_go_resistant">View</button>|
<modal id='ScorePlot' size='lg' title='UM0129480 7μM R02 exp85'>
{{:chemogenomics:cranks_plots:exp85.png?nolink}}
</modal>


<modal id="modal_hits" size="sm" title="Top 30 S/R Genes">
^Gene^CRANKS Score^FDR^
|[[:human_genes:S:SLC29A1|SLC29A1]]|-4.40|<0.01|
|[[:human_genes:T:TCF4|TCF4]]|-3.78|<0.01|
|[[:human_genes:P:PRKAG1|PRKAG1]]|-3.60|<0.01|
|[[:human_genes:P:PRKAA1|PRKAA1]]|-3.09|<0.01|
|[[:human_genes:O:OTUB1|OTUB1]]|-2.99|<0.01|
|[[:human_genes:W:WDR26|WDR26]]|-2.99|0.02|
|[[:human_genes:S:SMG7|SMG7]]|-2.85|0.05|
|[[:human_genes:T:TRIM44|TRIM44]]|-2.82|0.02|
|[[:human_genes:A:ATF4|ATF4]]|-2.81|0.02|
|[[:human_genes:T:TRAF2|TRAF2]]|-2.78|0.02|
|[[:human_genes:P:PRAMEF25|PRAMEF25]]|-2.68|0.43|
|[[:human_genes:P:PRAMEF26|PRAMEF26]]|-2.67|0.44|
|[[:human_genes:B:BSG|BSG]]|-2.61|0.04|
|[[:human_genes:I:IPO11|IPO11]]|-2.60|0.02|
|[[:human_genes:Y:YPEL5|YPEL5]]|-2.54|0.03|
|[[:human_genes:R:RPL30|RPL30]]|-2.53|0.13|
|[[:human_genes:B:BCOR|BCOR]]|-2.50|0.03|
|[[:human_genes:S:SMG9|SMG9]]|-2.46|0.05|
|[[:human_genes:G:GLE1|GLE1]]|-2.46|0.40|
|[[:human_genes:T:TBK1|TBK1]]|-2.45|0.05|
|[[:human_genes:G:GP2|GP2]]|-2.43|0.04|
|[[:human_genes:T:TSC2|TSC2]]|-2.40|0.05|
|[[:human_genes:M:MBTD1|MBTD1]]|-2.40|0.06|
|[[:human_genes:A:ATP13A1|ATP13A1]]|-2.38|0.05|
|[[:human_genes:R:RING1|RING1]]|-2.37|0.05|
|[[:human_genes:S:SLC2A13|SLC2A13]]|-2.35|0.05|
|[[:human_genes:M:MDM2|MDM2]]|-2.32|0.14|
|[[:human_genes:P:PRKACG|PRKACG]]|-2.31|0.05|
|[[:human_genes:P:PCYT1A|PCYT1A]]|-2.29|0.06|
|[[:human_genes:T:TCF12|TCF12]]|-2.29|0.10|
|[[:human_genes:S:SEPSECS|SEPSECS]]|2.58|0.04|
|[[:human_genes:E:ELP6|ELP6]]|2.58|<0.01|
|[[:human_genes:T:THG1L|THG1L]]|2.60|<0.01|
|[[:human_genes:V:VDAC2|VDAC2]]|2.66|<0.01|
|[[:human_genes:C:COA3|COA3]]|2.67|<0.01|
|[[:human_genes:P:PMAIP1|PMAIP1]]|2.67|<0.01|
|[[:human_genes:G:GLRX5|GLRX5]]|2.67|0.06|
|[[:human_genes:Z:ZCRB1|ZCRB1]]|2.67|0.01|
|[[:human_genes:D:DDX39A|DDX39A]]|2.71|<0.01|
|[[:human_genes:P:PUS3|PUS3]]|2.75|<0.01|
|[[:human_genes:F:FBXO11|FBXO11]]|2.88|<0.01|
|[[:human_genes:T:TXNIP|TXNIP]]|2.89|<0.01|
|[[:human_genes:R:RFK|RFK]]|2.93|<0.01|
|[[:human_genes:K:KCTD5|KCTD5]]|3.10|<0.01|
|[[:human_genes:O:OMA1|OMA1]]|3.25|0.00|
|[[:human_genes:E:ENY2|ENY2]]|3.31|<0.01|
|[[:human_genes:C:CMAS|CMAS]]|3.33|0.00|
|[[:human_genes:I:IBA57|IBA57]]|3.35|0.00|
|[[:human_genes:N:NFU1|NFU1]]|3.40|<0.01|
|[[:human_genes:D:DPH2|DPH2]]|3.47|0.00|
|[[:human_genes:S:STARD7|STARD7]]|3.60|0.00|
|[[:human_genes:P:PTAR1|PTAR1]]|3.73|0.00|
|[[:human_genes:U:UBQLN1|UBQLN1]]|3.87|0.00|
|[[:human_genes:B:BAK1|BAK1]]|3.93|0.00|
|[[:human_genes:D:DPH5|DPH5]]|4.01|0.00|
|[[:human_genes:D:DPH1|DPH1]]|4.13|0.00|
|[[:human_genes:P:PPP6C|PPP6C]]|4.46|0.00|
|[[:human_genes:D:DPH3|DPH3]]|4.57|0.00|
|[[:human_genes:R:RBM26|RBM26]]|4.69|0.00|
|[[:human_genes:M:MARCH5|MARCH5]]|4.97|0.00|
</modal>


<modal id="modal_screen_similarity" size="lg" title="Correlated Screens">
^Screen^Correlation^Plot^
|[[:results:exp492|iCRT14 30μM R08 exp492]]|0.09|<button type="primary" size="small" modal="1">View</button>|
|[[:results:exp38|Wortmannin 5μM R00 exp38]]|0.07|<button type="primary" size="small" modal="2">View</button>|
|[[:results:exp259|6-Thio-2-deoxyguanosine 2μM R06 exp259]]|0.097|<button type="primary" size="small" modal="3">View</button>|
|[[:results:exp450|Artemisinin 50μM R08 exp450]]|0.094|<button type="primary" size="small" modal="4">View</button>|
|[[:results:exp357|Dorsomorphin 5μM R07 exp357]]|0.079|<button type="primary" size="small" modal="5">View</button>|
|[[:results:exp116|AICAR 240μM R03 exp116]]|0.078|<button type="primary" size="small" modal="6">View</button>|
|[[:results:exp459|Bleomycin 5μM R08 exp459]]|0.075|<button type="primary" size="small" modal="7">View</button>|
|[[:results:exp451|Atovaquone 15μM R08 exp451]]|0.075|<button type="primary" size="small" modal="8">View</button>|
|[[:results:exp80|RO-3307 4.7μM R02 exp80]]|0.071|<button type="primary" size="small" modal="9">View</button>|
|[[:results:exp134|MS023 2μM R03 exp134]]|0.071|<button type="primary" size="small" modal="10">View</button>|
|[[:results:exp3|Actinomycin-D 0.001μM R00 exp3]]|0.071|<button type="primary" size="small" modal="11">View</button>|
|[[:results:exp456|Benzoate 20000μM R08 exp456]]|0.07|<button type="primary" size="small" modal="12">View</button>|
|[[:results:exp488|Hippuristanol 0.12μM R08 exp488]]|0.069|<button type="primary" size="small" modal="13">View</button>|
|[[:results:exp135|MS023 7μM R03 exp135]]|0.069|<button type="primary" size="small" modal="14">View</button>|
|[[:results:exp485|GSK626616 14μM R08 exp485]]|0.069|<button type="primary" size="small" modal="15">View</button>|
|[[:results:exp199|Etoposide 0.3μM R05 exp199]]|0.068|<button type="primary" size="small" modal="16">View</button>|
|[[:results:exp472|CI-1040 9.5μM R08 exp472]]|0.067|<button type="primary" size="small" modal="17">View</button>|
|[[:results:exp443|SNS-032 15μM R08 exp443]]|0.067|<button type="primary" size="small" modal="18">View</button>|
|[[:results:exp502|Milciclib 2μM R08 exp502]]|0.066|<button type="primary" size="small" modal="19">View</button>|
|[[:results:exp67|BVD-523 15μM R02 exp67]]|0.066|<button type="primary" size="small" modal="20">View</button>|
|[[:results:exp440|Aphidicolin 0.4μM R08 exp440]]|0.064|<button type="primary" size="small" modal="21">View</button>|
|[[:results:exp503|Mitomycin-C 0.06μM R08 exp503]]|0.064|<button type="primary" size="small" modal="22">View</button>|
|[[:results:exp214|2-Deoxy-D-glucose 800μM R05 exp214]]|0.063|<button type="primary" size="small" modal="23">View</button>|
|[[:results:exp512|Olaparib 4μM R08 exp512]]|0.063|<button type="primary" size="small" modal="24">View</button>|
|[[:results:exp515|PU-H71 1μM R08 exp515]]|0.061|<button type="primary" size="small" modal="25">View</button>|
|[[:results:exp363|GSK-J4 1-1.25μM to day4 R07 exp363]]|0.061|<button type="primary" size="small" modal="26">View</button>|
|[[:results:exp524|Staurosporine 0.02μM R08 exp524]]|0.061|<button type="primary" size="small" modal="27">View</button>|
|[[:results:exp489|Hippuristanol 0.12μM R08 exp489 no dilution day6]]|0.06|<button type="primary" size="small" modal="28">View</button>|
|[[:results:exp2|5-Fluorouracil 20μM R00 exp2]]|0.059|<button type="primary" size="small" modal="29">View</button>|
|[[:results:exp527|Tanespimycin 14μM R08 exp527]]|0.059|<button type="primary" size="small" modal="30">View</button>|
|[[:results:exp445|∆-9-Tetrahydrocannabinol 30μM R08 exp445]]|0.059|<button type="primary" size="small" modal="31">View</button>|
|[[:results:exp28|Pimelic-diphenylamide-106 5μM R00 exp28]]|0.058|<button type="primary" size="small" modal="32">View</button>|
|[[:results:exp34|Rotenone 20μM R00 exp34]]|0.056|<button type="primary" size="small" modal="33">View</button>|
|[[:results:exp66|BI-D1870 3.15μM R02 exp66]]|0.055|<button type="primary" size="small" modal="34">View</button>|
|[[:results:exp234|Ethanol 0.01 R05 exp234]]|0.055|<button type="primary" size="small" modal="35">View</button>|
|[[:results:exp19|Etoposide 1μM R00 exp19]]|0.055|<button type="primary" size="small" modal="36">View</button>|
|[[:results:exp468|CB-5083 0.4μM R08 exp468]]|0.054|<button type="primary" size="small" modal="37">View</button>|
|[[:results:exp211|AICAR 240μM R05 exp211]]|0.053|<button type="primary" size="small" modal="38">View</button>|
|[[:results:exp359|FK-506 30μM R07 exp359]]|0.053|<button type="primary" size="small" modal="39">View</button>|
|[[:results:exp227|Cryptotanshinone 12μM R05 exp227]]|0.053|<button type="primary" size="small" modal="40">View</button>|
|[[:results:exp466|Cannabidiol 20μM R08 exp466]]|0.053|<button type="primary" size="small" modal="41">View</button>|
|[[:results:exp355|Dinaciclib 0.007μM R07 exp355]]|0.053|<button type="primary" size="small" modal="42">View</button>|
|[[:results:exp269|Bisphenol A 100μM R06 exp269]]|0.052|<button type="primary" size="small" modal="43">View</button>|
|[[:results:exp441|GSK-J4 1.5μM R08 exp441]]|0.052|<button type="primary" size="small" modal="44">View</button>|
|[[:results:exp478|Doxorubicin 0.02μM R08 exp478]]|0.051|<button type="primary" size="small" modal="45">View</button>|
</modal>


<modal id="1" size="lg" title="UM0129480 7μM R02 exp85  vs  iCRT14 30μM R08 exp492">
{{:chemogenomics:comparison_plots:exp492_vs_exp85.png?nolink |}}
</modal>

<modal id="2" size="lg" title="UM0129480 7μM R02 exp85  vs  Wortmannin 5μM R00 exp38">
{{:chemogenomics:comparison_plots:exp38_vs_exp85.png?nolink |}}
</modal>

<modal id="3" size="lg" title="6-Thio-2-deoxyguanosine 2μM R06 exp259  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp259_vs_exp85.png?nolink |}}
</modal>

<modal id="4" size="lg" title="Artemisinin 50μM R08 exp450  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp450_vs_exp85.png?nolink |}}
</modal>

<modal id="5" size="lg" title="Dorsomorphin 5μM R07 exp357  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp357_vs_exp85.png?nolink |}}
</modal>

<modal id="6" size="lg" title="AICAR 240μM R03 exp116  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp116_vs_exp85.png?nolink |}}
</modal>

<modal id="7" size="lg" title="Bleomycin 5μM R08 exp459  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp459_vs_exp85.png?nolink |}}
</modal>

<modal id="8" size="lg" title="Atovaquone 15μM R08 exp451  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp451_vs_exp85.png?nolink |}}
</modal>

<modal id="9" size="lg" title="RO-3307 4.7μM R02 exp80  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp80_vs_exp85.png?nolink |}}
</modal>

<modal id="10" size="lg" title="MS023 2μM R03 exp134  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp134_vs_exp85.png?nolink |}}
</modal>

<modal id="11" size="lg" title="Actinomycin-D 0.001μM R00 exp3  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp3_vs_exp85.png?nolink |}}
</modal>

<modal id="12" size="lg" title="Benzoate 20000μM R08 exp456  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp456_vs_exp85.png?nolink |}}
</modal>

<modal id="13" size="lg" title="Hippuristanol 0.12μM R08 exp488  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp488_vs_exp85.png?nolink |}}
</modal>

<modal id="14" size="lg" title="MS023 7μM R03 exp135  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp135_vs_exp85.png?nolink |}}
</modal>

<modal id="15" size="lg" title="GSK626616 14μM R08 exp485  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp485_vs_exp85.png?nolink |}}
</modal>

<modal id="16" size="lg" title="Etoposide 0.3μM R05 exp199  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp199_vs_exp85.png?nolink |}}
</modal>

<modal id="17" size="lg" title="CI-1040 9.5μM R08 exp472  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp472_vs_exp85.png?nolink |}}
</modal>

<modal id="18" size="lg" title="SNS-032 15μM R08 exp443  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp443_vs_exp85.png?nolink |}}
</modal>

<modal id="19" size="lg" title="Milciclib 2μM R08 exp502  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp502_vs_exp85.png?nolink |}}
</modal>

<modal id="20" size="lg" title="BVD-523 15μM R02 exp67  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp67_vs_exp85.png?nolink |}}
</modal>

<modal id="21" size="lg" title="Aphidicolin 0.4μM R08 exp440  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp440_vs_exp85.png?nolink |}}
</modal>

<modal id="22" size="lg" title="Mitomycin-C 0.06μM R08 exp503  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp503_vs_exp85.png?nolink |}}
</modal>

<modal id="23" size="lg" title="2-Deoxy-D-glucose 800μM R05 exp214  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp214_vs_exp85.png?nolink |}}
</modal>

<modal id="24" size="lg" title="Olaparib 4μM R08 exp512  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp512_vs_exp85.png?nolink |}}
</modal>

<modal id="25" size="lg" title="PU-H71 1μM R08 exp515  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp515_vs_exp85.png?nolink |}}
</modal>

<modal id="26" size="lg" title="GSK-J4 1-1.25μM to day4 R07 exp363  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp363_vs_exp85.png?nolink |}}
</modal>

<modal id="27" size="lg" title="Staurosporine 0.02μM R08 exp524  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp524_vs_exp85.png?nolink |}}
</modal>

<modal id="28" size="lg" title="Hippuristanol 0.12μM R08 exp489 no dilution day6  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp489_vs_exp85.png?nolink |}}
</modal>

<modal id="29" size="lg" title="5-Fluorouracil 20μM R00 exp2  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp2_vs_exp85.png?nolink |}}
</modal>

<modal id="30" size="lg" title="Tanespimycin 14μM R08 exp527  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp527_vs_exp85.png?nolink |}}
</modal>

<modal id="31" size="lg" title="∆-9-Tetrahydrocannabinol 30μM R08 exp445  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp445_vs_exp85.png?nolink |}}
</modal>

<modal id="32" size="lg" title="Pimelic-diphenylamide-106 5μM R00 exp28  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp28_vs_exp85.png?nolink |}}
</modal>

<modal id="33" size="lg" title="Rotenone 20μM R00 exp34  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp34_vs_exp85.png?nolink |}}
</modal>

<modal id="34" size="lg" title="BI-D1870 3.15μM R02 exp66  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp66_vs_exp85.png?nolink |}}
</modal>

<modal id="35" size="lg" title="Ethanol 0.01 R05 exp234  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp234_vs_exp85.png?nolink |}}
</modal>

<modal id="36" size="lg" title="Etoposide 1μM R00 exp19  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp19_vs_exp85.png?nolink |}}
</modal>

<modal id="37" size="lg" title="CB-5083 0.4μM R08 exp468  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp468_vs_exp85.png?nolink |}}
</modal>

<modal id="38" size="lg" title="AICAR 240μM R05 exp211  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp211_vs_exp85.png?nolink |}}
</modal>

<modal id="39" size="lg" title="FK-506 30μM R07 exp359  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp359_vs_exp85.png?nolink |}}
</modal>

<modal id="40" size="lg" title="Cryptotanshinone 12μM R05 exp227  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp227_vs_exp85.png?nolink |}}
</modal>

<modal id="41" size="lg" title="Cannabidiol 20μM R08 exp466  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp466_vs_exp85.png?nolink |}}
</modal>

<modal id="42" size="lg" title="Dinaciclib 0.007μM R07 exp355  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp355_vs_exp85.png?nolink |}}
</modal>

<modal id="43" size="lg" title="Bisphenol A 100μM R06 exp269  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp269_vs_exp85.png?nolink |}}
</modal>

<modal id="44" size="lg" title="GSK-J4 1.5μM R08 exp441  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp441_vs_exp85.png?nolink |}}
</modal>

<modal id="45" size="lg" title="Doxorubicin 0.02μM R08 exp478  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp478_vs_exp85.png?nolink |}}
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<modal id="modal_go_sensitive" size="lg" title="Top 30 sensitive GO terms">
^GO Term^Fold Change^Genes^
|cAMP-dependent protein kinase activity|355.37|PRKAG1,PRKAA1,PRKACG|
|cyclic nucleotide-dependent protein kinase activity|253.84|PRKAG1,PRKAA1,PRKACG|
|regulation of TORC1 signaling|27.55|PRKAA1,OTUB1,TBK1,TSC2|
|transferase complex|7.13|PRKAG1,PRKAA1,WDR26,TRAF2,YPEL5,BCOR,TBK1,MBTD1,RING1,PRKACG|
|intracellular protein-containing complex|6.07|PRKAG1,PRKAA1,WDR26,TRAF2,YPEL5,BCOR,MBTD1,RING1,PRKACG|
</modal>
<modal id="modal_go_resistant" size="lg" title="Top 30 resistant GO terms">
^GO Term^Fold Change^Genes^
|protein histidyl modification to diphthamide|442.24|DPH3,DPH1,DPH5,DPH2|
|peptidyl-histidine modification|236.91|DPH3,DPH5,DPH2|
|porin activity|221.12|BAK1,VDAC2|
|metallo-sulfur cluster assembly|59.23|NFU1,IBA57,GLRX5|
|iron-sulfur cluster assembly|59.23|NFU1,IBA57,GLRX5|
|positive regulation of response to endoplasmic reticulum stress|47.38|BAK1,UBQLN1,PMAIP1|
|metal cluster binding|33.00|DPH1,DPH2,NFU1,GLRX5|
|iron-sulfur cluster binding|33.00|DPH1,DPH2,NFU1,GLRX5|
|tRNA modification|31.06|DPH3,PUS3,THG1L,ELP6,SEPSECS|
|tRNA processing|21.94|DPH3,PUS3,THG1L,ELP6,SEPSECS|
|mitochondrial membrane organization|20.86|BAK1,OMA1,PMAIP1,VDAC2|
|mitochondrial outer membrane|15.95|MARCHF5,BAK1,STARD7,PMAIP1,VDAC2,THG1L|
|tRNA metabolic process|14.78|DPH3,PUS3,THG1L,ELP6,SEPSECS|
|organelle outer membrane|14.05|MARCHF5,BAK1,STARD7,PMAIP1,VDAC2,THG1L|
|outer membrane|13.94|MARCHF5,BAK1,STARD7,PMAIP1,VDAC2,THG1L|
|mitochondrial membrane|6.26|MARCHF5,BAK1,STARD7,OMA1,PMAIP1,COA3,VDAC2,THG1L|
|mitochondrial envelope|5.88|MARCHF5,BAK1,STARD7,OMA1,PMAIP1,COA3,VDAC2,THG1L|
</modal>