======= ANKRD40 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: ANKRD40
  * **<color #00a2e8>Official Name</color>**: ankyrin repeat domain 40
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=91369|91369]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q6AI12|Q6AI12]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=ANKRD40&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20ANKRD40|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**:  N/A

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='primary' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
|Ank 2|
|Ank|
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|cellular component|
|molecular function|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='default' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp134|MS023 2μM R03 exp134]]|-2.52|
|[[:results:exp222|Betulinic acid 10 to 15μM on day4 R05 exp222]]|-1.95|
|[[:results:exp189|Temozolomide 200μM R04 exp189]]|-1.79|
|[[:results:exp6|Bortezomib 0.005μM R00 exp6]]|1.7|
|[[:results:exp281|Disulfiram 4.3μM R06 exp281]]|1.71|
|[[:results:exp61|YM155 0.0002μM R01 exp61]]|1.71|
|[[:results:exp11|CCCP 1μM R00 exp11]]|1.74|
|[[:results:exp282|Fluvastatin 2.2μM R06 exp282]]|1.74|
|[[:results:exp13|Chloramphenicol 20μM R00 exp13]]|1.79|
|[[:results:exp50|Nicotinamide 2000μM R01 exp50]]|1.82|
|[[:results:exp68|Clomiphene 4.4μM R02 exp68]]|1.83|
|[[:results:exp302|35°C R06 exp302]]|1.84|
|[[:results:exp183|IU1-C 25μM R04 exp183]]|1.84|
|[[:results:exp464|Calcipotriol 5μM R08 exp464]]|1.86|
|[[:results:exp130|JQ1 0.01μM R03 exp130]]|1.86|
|[[:results:exp406|Thalidomide 20μM R07 exp406]]|1.87|
|[[:results:exp36|TRAIL 50ng/ml R00 exp36]]|1.88|
|[[:results:exp31|Rifampicin 1μM R00 exp31]]|1.9|
|[[:results:exp438|NN-Diethyl-meta-toluamide 500μM R08 exp438]]|1.93|
|[[:results:exp493|IL-3 9ng/ml R08 exp493]]|1.94|
|[[:results:exp457|Bisphenol F 50μM R08 exp457]]|1.96|
|[[:results:exp209|Deguelin 0.15μM R05 exp209]]|1.99|
|[[:results:exp10|CCCP 0.1μM R00 exp10]]|2|
|[[:results:exp520|Rucaparib 6.5μM R08 exp520]]|2.02|
|[[:results:exp476|Dihydrosphingosine 8μM R08 exp476]]|2.13|
|[[:results:exp58|UM131593 0.1μM R01 exp58]]|2.15|
|[[:results:exp288|HMS-I2 10μM R06 exp288]]|2.18|
|[[:results:exp32|Rifampicin 10μM R00 exp32]]|2.45|
|[[:results:exp12|Chloramphenicol 2μM R00 exp12]]|2.51|
|[[:results:exp495|IWR1 50μM R08 exp495]]|2.52|
|[[:results:exp101|Nicotinamide 1000μM R03 exp101]]|2.57|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
No correlation found to any other genes in chemogenomics.
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 0/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|0/1|
|909776.0|0/1|
|bile duct|0/28|
|blood|0/28|
|bone|0/26|
|breast|0/33|
|central nervous system|0/56|
|cervix|0/4|
|colorectal|0/17|
|esophagus|0/13|
|fibroblast|0/1|
|gastric|0/16|
|kidney|0/21|
|liver|0/20|
|lung|0/75|
|lymphocyte|0/16|
|ovary|0/26|
|pancreas|0/24|
|peripheral nervous system|0/16|
|plasma cell|0/15|
|prostate|0/1|
|skin|0/24|
|soft tissue|0/9|
|thyroid|0/2|
|upper aerodigestive|0/22|
|urinary tract|0/29|
|uterus|0/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 1097
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 6.24 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='ANKRD40 Expression in NALM6 Cells: 6.24'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>