======= C11orf57 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: NKAPD1
  * **<color #00a2e8>Official Name</color>**: NKAP domain containing 1
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=55216|55216]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q6ZUT1|Q6ZUT1]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=C11orf57&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20C11orf57|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**:  N/A

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='default' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='default' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
No Pfam Domain information is available for this gene.
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
No GO term information is available for this gene.
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp272|CHIR-124 0.04μM R06 exp272]]|-2.03|
|[[:results:exp113|1-Methyl-nicotinamide-chloride 1000μM R03 exp113]]|-1.74|
|[[:results:exp264|Arsenate 40μM R06 exp264]]|1.71|
|[[:results:exp435|JQ1 0.8μM R08 exp435]]|1.75|
|[[:results:exp28|Pimelic-diphenylamide-106 5μM R00 exp28]]|1.92|
|[[:results:exp466|Cannabidiol 20μM R08 exp466]]|1.93|
|[[:results:exp365|I-BRD9 4μM R07 exp365]]|2.06|
|[[:results:exp485|GSK626616 14μM R08 exp485]]|2.14|
|[[:results:exp487|Hinokiflavone 12μM R08 exp487]]|2.26|
|[[:results:exp536|Vitamin-D3 40μM R08 exp536]]|2.36|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:b:bcs1l|BCS1L]]|0.48|
|[[:human genes:c:cxorf56|CXorf56]]|0.47|
|[[:human genes:r:rabggtb|RABGGTB]]|0.461|
|[[:human genes:z:znhit1|ZNHIT1]]|0.454|
|[[:human genes:t:triap1|TRIAP1]]|0.453|
|[[:human genes:g:gemin7|GEMIN7]]|0.452|
|[[:human genes:s:sco2|SCO2]]|0.44|
|[[:human genes:r:rpe|RPE]]|0.438|
|[[:human genes:s:selrc1|SELRC1]]|0.437|
|[[:human genes:f:fh|FH]]|0.434|
|[[:human genes:u:uap1|UAP1]]|0.432|
|[[:human genes:d:dhrsx|DHRSX]]|0.426|
|[[:human genes:h:hsd17b10|HSD17B10]]|0.419|
|[[:human genes:v:vezt|VEZT]]|0.41|
|[[:human genes:p:ppp4c|PPP4C]]|0.407|
|[[:human genes:h:hccs|HCCS]]|0.407|
|[[:human genes:f:fastkd5|FASTKD5]]|0.402|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 27/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|0/1|
|909776.0|0/1|
|bile duct|2/28|
|blood|0/28|
|bone|1/26|
|breast|2/33|
|central nervous system|3/56|
|cervix|1/4|
|colorectal|0/17|
|esophagus|0/13|
|fibroblast|0/1|
|gastric|0/16|
|kidney|2/21|
|liver|0/20|
|lung|2/75|
|lymphocyte|0/16|
|ovary|2/26|
|pancreas|1/24|
|peripheral nervous system|2/16|
|plasma cell|0/15|
|prostate|0/1|
|skin|3/24|
|soft tissue|0/9|
|thyroid|0/2|
|upper aerodigestive|2/22|
|urinary tract|0/29|
|uterus|0/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 3189
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 6.43 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='C11ORF57 Expression in NALM6 Cells: 6.43'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>