======= C2orf82 ======= == Gene Information == * **Official Symbol**: SNORC * **Official Name**: secondary ossification center associated regulator of chondrocyte maturation * **Aliases and Previous Symbols**: N/A * **Entrez ID**: [[https://www.ncbi.nlm.nih.gov/gene/?term=389084|389084]] * **UniProt**: [[https://www.uniprot.org/uniprot/Q6UX34|Q6UX34]] * **Interactions**: [[https://thebiogrid.org/search.php?search=C2orf82&organism=9606|BioGRID]] * **PubMed articles**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20C2orf82|Open PubMed]] * **OMIM**: [[https://omim.org/entry/620882|Open OMIM]] == Function Summary == * **Entrez Summary**: N/A * **UniProt Summary**: Plays a role in the regulation of chondrocyte maturation and postnatal endochondral ossification. May inhibit cell growth stimulation induced by FGF2. {ECO:0000250|UniProtKB:Q9CXL7}. No Pfam Domain information is available for this gene. |cell periphery| |cartilage development| |connective tissue development| |collagen-containing extracellular matrix| |skeletal system development| |tissue development| \\ === CRISPR Data === No hits were found. No correlation found to any other genes in chemogenomics. Global Fraction of Cell Lines Where Essential: 1/739 ^Tissue^Fraction Of Cell Lines Where Essential^ |1290807.0|0/1| |909776.0|0/1| |bile duct|0/28| |blood|0/28| |bone|0/26| |breast|0/33| |central nervous system|0/56| |cervix|0/4| |colorectal|0/17| |esophagus|0/13| |fibroblast|0/1| |gastric|0/16| |kidney|0/21| |liver|0/20| |lung|0/75| |lymphocyte|0/16| |ovary|0/26| |pancreas|0/24| |peripheral nervous system|0/16| |plasma cell|0/15| |prostate|0/1| |skin|0/24| |soft tissue|0/9| |thyroid|0/2| |upper aerodigestive|0/22| |urinary tract|0/29| |uterus|0/5| == Essentiality in NALM6 == * **Essentiality Rank**: 13307 * **Expression level (log2 read counts)**: 1.02 {{:chemogenomics:nalm6 dist.png?nolink |}}