======= C7orf43 ======= == Gene Information == * **Official Symbol**: MAP11 * **Official Name**: microtubule associated protein 11 * **Aliases and Previous Symbols**: N/A * **Entrez ID**: [[https://www.ncbi.nlm.nih.gov/gene/?term=55262|55262]] * **UniProt**: [[https://www.uniprot.org/uniprot/Q8WVR3|Q8WVR3]] * **Interactions**: [[https://thebiogrid.org/search.php?search=C7orf43&organism=9606|BioGRID]] * **PubMed articles**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20C7orf43|Open PubMed]] * **OMIM**: N/A == Function Summary == * **Entrez Summary**: N/A * **UniProt Summary**: N/A No Pfam Domain information is available for this gene. |alpha-tubulin binding| |mitotic spindle| |midbody| |microtubule organizing center| |intracellular membrane-bounded organelle| |regulation of cell population proliferation| \\ === CRISPR Data === ^Screen^Score^ |[[:results:exp89|Vemurafenib 6.6μM R02 exp89]]|-1.88| |[[:results:exp219|A-395N 10μM R05 exp219]]|1.76| |[[:results:exp162|BI-D1870 2μM R04 exp162]]|1.79| No correlation found to any other genes in chemogenomics. Global Fraction of Cell Lines Where Essential: 0/739 ^Tissue^Fraction Of Cell Lines Where Essential^ |1290807.0|0/1| |909776.0|0/1| |bile duct|0/28| |blood|0/28| |bone|0/26| |breast|0/33| |central nervous system|0/56| |cervix|0/4| |colorectal|0/17| |esophagus|0/13| |fibroblast|0/1| |gastric|0/16| |kidney|0/21| |liver|0/20| |lung|0/75| |lymphocyte|0/16| |ovary|0/26| |pancreas|0/24| |peripheral nervous system|0/16| |plasma cell|0/15| |prostate|0/1| |skin|0/24| |soft tissue|0/9| |thyroid|0/2| |upper aerodigestive|0/22| |urinary tract|0/29| |uterus|0/5| == Essentiality in NALM6 == * **Essentiality Rank**: 10380 * **Expression level (log2 read counts)**: 4.78 {{:chemogenomics:nalm6 dist.png?nolink |}}