======= CCDC154 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: CCDC154
  * **<color #00a2e8>Official Name</color>**: coiled-coil domain containing 154
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=645811|645811]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/A6NI56|A6NI56]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=CCDC154&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20CCDC154|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: [[https://omim.org/entry/618740|Open OMIM]]

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='default' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
No Pfam Domain information is available for this gene.
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|bone mineralization involved in bone maturation|
|tooth eruption|
|ossification involved in bone maturation|
|bone maturation|
|animal organ maturation|
|bone resorption|
|bone remodeling|
|bone mineralization|
|odontogenesis of dentin-containing tooth|
|biomineral tissue development|
|biomineralization|
|tissue remodeling|
|odontogenesis|
|anatomical structure maturation|
|tissue homeostasis|
|bone development|
|developmental maturation|
|early endosome|
|ossification|
|multicellular organismal homeostasis|
|anatomical structure homeostasis|
|skeletal system development|
|animal organ morphogenesis|
|homeostatic process|
|tissue development|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='default' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp27|Pimelic-diphenylamide-106 0.5μM R00 exp27]]|-1.75|
|[[:results:exp277|Curcumin 6.5μM R06 exp277]]|1.7|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
No correlation found to any other genes in chemogenomics.
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: N/A
^Tissue^Fraction Of Cell Lines Where Essential^
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 18224
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 3.2 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='CCDC154 Expression in NALM6 Cells: 3.2'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>