======= CGB2 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: CGB2
  * **<color #00a2e8>Official Name</color>**: chorionic gonadotropin subunit beta 2
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=114336|114336]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q6NT52|Q6NT52]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=CGB2&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20CGB2|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: [[https://omim.org/entry/608824|Open OMIM]]

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='primary' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
|Cys knot|
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|hormone activity|
|hormone-mediated signaling pathway|
|cellular response to hormone stimulus|
|response to hormone|
|cellular response to endogenous stimulus|
|G protein-coupled receptor signaling pathway|
|response to endogenous stimulus|
|extracellular space|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp425|Beta-Estradiol 0.55μM R07 exp425]]|1.77|
|[[:results:exp291|LLY-284 2.6μM R06 exp291]]|1.82|
|[[:results:exp219|A-395N 10μM R05 exp219]]|1.91|
|[[:results:exp422|Wiskostatin 3μM R07 exp422]]|1.91|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:v:vasn|VASN]]|0.527|
|[[:human genes:c:cdc73|CDC73]]|0.525|
|[[:human genes:c:c1qtnf9b|C1QTNF9B]]|0.523|
|[[:human genes:t:tbc1d3h|TBC1D3H]]|0.516|
|[[:human genes:t:tbc1d3c|TBC1D3C]]|0.515|
|[[:human genes:p:pde4dip|PDE4DIP]]|0.511|
|[[:human genes:t:ticrr|TICRR]]|0.491|
|[[:human genes:w:wdr75|WDR75]]|0.489|
|[[:human genes:c:cope|COPE]]|0.487|
|[[:human genes:s:supt5h|SUPT5H]]|0.487|
|[[:human genes:t:tceb3cl2|TCEB3CL2]]|0.487|
|[[:human genes:p:psmb4|PSMB4]]|0.485|
|[[:human genes:t:tbc1d3g|TBC1D3G]]|0.484|
|[[:human genes:t:tbc1d3k|TBC1D3K]]|0.48|
|[[:human genes:t:tbc1d3e|TBC1D3E]]|0.48|
|[[:human genes:t:tbc1d3l|TBC1D3L]]|0.48|
|[[:human genes:t:tbc1d3i|TBC1D3I]]|0.48|
|[[:human genes:r:rrn3|RRN3]]|0.479|
|[[:human genes:t:tbc1d3f|TBC1D3F]]|0.476|
|[[:human genes:p:pola1|POLA1]]|0.475|
|[[:human genes:k:krt78|KRT78]]|0.475|
|[[:human genes:z:znf830|ZNF830]]|0.474|
|[[:human genes:e:exosc5|EXOSC5]]|0.473|
|[[:human genes:t:tbc1d3|TBC1D3]]|0.47|
|[[:human genes:p:psmd3|PSMD3]]|0.47|
|[[:human genes:c:cep192|CEP192]]|0.47|
|[[:human genes:p:psmb3|PSMB3]]|0.47|
|[[:human genes:p:psma6|PSMA6]]|0.468|
|[[:human genes:t:tceb3c|TCEB3C]]|0.467|
|[[:human genes:t:twistnb|TWISTNB]]|0.466|
|[[:human genes:s:supt6h|SUPT6H]]|0.466|
|[[:human genes:c:cbwd5|CBWD5]]|0.465|
|[[:human genes:t:trim52|TRIM52]]|0.463|
|[[:human genes:n:nup160|NUP160]]|0.461|
|[[:human genes:p:pole|POLE]]|0.461|
|[[:human genes:p:psma7|PSMA7]]|0.457|
|[[:human genes:m:mt1e|MT1E]]|0.457|
|[[:human genes:e:exosc9|EXOSC9]]|0.453|
|[[:human genes:g:golga8o|GOLGA8O]]|0.453|
|[[:human genes:p:psmd11|PSMD11]]|0.453|
|[[:human genes:t:tceb3cl|TCEB3CL]]|0.453|
|[[:human genes:n:npipb8|NPIPB8]]|0.451|
|[[:human genes:m:myo1h|MYO1H]]|0.45|
|[[:human genes:p:psmb2|PSMB2]]|0.449|
|[[:human genes:r:rpf1|RPF1]]|0.449|
|[[:human genes:c:cbwd3|CBWD3]]|0.445|
|[[:human genes:z:znf219|ZNF219]]|0.445|
|[[:human genes:n:napa|NAPA]]|0.444|
|[[:human genes:p:psmd14|PSMD14]]|0.443|
|[[:human genes:c:c14orf93|C14orf93]]|0.442|
|[[:human genes:s:sf3a3|SF3A3]]|0.44|
|[[:human genes:m:myo18a|MYO18A]]|0.439|
|[[:human genes:e:exd1|EXD1]]|0.439|
|[[:human genes:h:hist2h3a|HIST2H3A]]|0.439|
|[[:human genes:h:hist2h3c|HIST2H3C]]|0.438|
|[[:human genes:p:psmb1|PSMB1]]|0.438|
|[[:human genes:p:pold1|POLD1]]|0.437|
|[[:human genes:c:col2a1|COL2A1]]|0.436|
|[[:human genes:k:kctd17|KCTD17]]|0.435|
|[[:human genes:a:ankle2|ANKLE2]]|0.435|
|[[:human genes:x:xylt2|XYLT2]]|0.435|
|[[:human genes:s:ssh2|SSH2]]|0.433|
|[[:human genes:f:fam25b|FAM25B]]|0.432|
|[[:human genes:c:chd4|CHD4]]|0.432|
|[[:human genes:k:kiaa0947|KIAA0947]]|0.431|
|[[:human genes:p:pan3|PAN3]]|0.43|
|[[:human genes:t:tsg101|TSG101]]|0.429|
|[[:human genes:o:orc6|ORC6]]|0.428|
|[[:human genes:d:dnm2|DNM2]]|0.427|
|[[:human genes:r:rrp15|RRP15]]|0.427|
|[[:human genes:m:myh7b|MYH7B]]|0.426|
|[[:human genes:p:paf1|PAF1]]|0.426|
|[[:human genes:a:arcn1|ARCN1]]|0.426|
|[[:human genes:i:iscu|ISCU]]|0.426|
|[[:human genes:c:chaf1a|CHAF1A]]|0.424|
|[[:human genes:r:rpl35|RPL35]]|0.424|
|[[:human genes:e:exosc6|EXOSC6]]|0.424|
|[[:human genes:r:rps9|RPS9]]|0.424|
|[[:human genes:m:madcam1|MADCAM1]]|0.422|
|[[:human genes:r:rbm39|RBM39]]|0.421|
|[[:human genes:z:znf541|ZNF541]]|0.421|
|[[:human genes:s:sf3a1|SF3A1]]|0.42|
|[[:human genes:c:cbwd6|CBWD6]]|0.42|
|[[:human genes:t:tfip11|TFIP11]]|0.42|
|[[:human genes:e:eif4a3|EIF4A3]]|0.42|
|[[:human genes:c:ccdc94|CCDC94]]|0.418|
|[[:human genes:s:snip1|SNIP1]]|0.418|
|[[:human genes:p:psmc1|PSMC1]]|0.416|
|[[:human genes:e:ebna1bp2|EBNA1BP2]]|0.416|
|[[:human genes:r:rad51|RAD51]]|0.416|
|[[:human genes:z:znf106|ZNF106]]|0.415|
|[[:human genes:o:orc1|ORC1]]|0.414|
|[[:human genes:g:golga6l3|GOLGA6L3]]|0.413|
|[[:human genes:g:golga8r|GOLGA8R]]|0.413|
|[[:human genes:c:ccna2|CCNA2]]|0.412|
|[[:human genes:n:npipb5|NPIPB5]]|0.412|
|[[:human genes:c:cacna1a|CACNA1A]]|0.412|
|[[:human genes:p:psmd1|PSMD1]]|0.411|
|[[:human genes:t:tuba8|TUBA8]]|0.41|
|[[:human genes:z:znf655|ZNF655]]|0.41|
|[[:human genes:r:rfxank|RFXANK]]|0.41|
|[[:human genes:l:lrr1|LRR1]]|0.409|
|[[:human genes:c:cdc6|CDC6]]|0.409|
|[[:human genes:m:mcoln1|MCOLN1]]|0.407|
|[[:human genes:n:nol10|NOL10]]|0.407|
|[[:human genes:r:rpl14|RPL14]]|0.406|
|[[:human genes:p:ppm1d|PPM1D]]|0.406|
|[[:human genes:d:dock6|DOCK6]]|0.406|
|[[:human genes:r:rpl30|RPL30]]|0.406|
|[[:human genes:h:hgc6.3|HGC6.3]]|0.406|
|[[:human genes:m:mat2a|MAT2A]]|0.405|
|[[:human genes:u:upf1|UPF1]]|0.405|
|[[:human genes:m:med17|MED17]]|0.405|
|[[:human genes:p:psmd2|PSMD2]]|0.405|
|[[:human genes:m:mdm2|MDM2]]|0.405|
|[[:human genes:s:slc5a5|SLC5A5]]|0.404|
|[[:human genes:r:rps2|RPS2]]|0.404|
|[[:human genes:s:snrpa1|SNRPA1]]|0.404|
|[[:human genes:r:rbbp5|RBBP5]]|0.404|
|[[:human genes:c:ckap5|CKAP5]]|0.403|
|[[:human genes:c:cactin|CACTIN]]|0.403|
|[[:human genes:c:ccdc64b|CCDC64B]]|0.403|
|[[:human genes:r:rps28|RPS28]]|0.401|
|[[:human genes:i:ints6|INTS6]]|0.401|
|[[:human genes:f:fam20a|FAM20A]]|0.401|
|[[:human genes:c:cdc45|CDC45]]|0.401|
|[[:human genes:d:dtl|DTL]]|0.401|
|[[:human genes:g:gprin2|GPRIN2]]|0.401|
|[[:human genes:s:s1pr4|S1PR4]]|0.401|
|[[:human genes:b:bysl|BYSL]]|0.4|
|[[:human genes:s:slc6a17|SLC6A17]]|0.4|
|[[:human genes:m:mepce|MEPCE]]|0.4|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 0/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|0/1|
|909776.0|0/1|
|bile duct|0/28|
|blood|0/28|
|bone|0/26|
|breast|0/33|
|central nervous system|0/56|
|cervix|0/4|
|colorectal|0/17|
|esophagus|0/13|
|fibroblast|0/1|
|gastric|0/16|
|kidney|0/21|
|liver|0/20|
|lung|0/75|
|lymphocyte|0/16|
|ovary|0/26|
|pancreas|0/24|
|peripheral nervous system|0/16|
|plasma cell|0/15|
|prostate|0/1|
|skin|0/24|
|soft tissue|0/9|
|thyroid|0/2|
|upper aerodigestive|0/22|
|urinary tract|0/29|
|uterus|0/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 2064
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: -6.6 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='CGB2 Expression in NALM6 Cells: -6.6'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>