======= EGFLAM =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: EGFLAM
  * **<color #00a2e8>Official Name</color>**: EGF like, fibronectin type III and laminin G domains
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=133584|133584]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q63HQ2|Q63HQ2]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=EGFLAM&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20EGFLAM|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: [[https://omim.org/entry/617683|Open OMIM]]

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='primary' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
|Laminin G 1|
|Laminin G 2|
|fn3|
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan|
|interstitial matrix|
|glycosaminoglycan binding|
|chondroitin sulfate metabolic process|
|chondroitin sulfate proteoglycan metabolic process|
|substrate adhesion-dependent cell spreading|
|peptide cross-linking|
|basement membrane|
|proteoglycan metabolic process|
|mucopolysaccharide metabolic process|
|positive regulation of cell-substrate adhesion|
|glycosaminoglycan metabolic process|
|aminoglycan metabolic process|
|cell-substrate adhesion|
|peptidyl-serine modification|
|regulation of cell-substrate adhesion|
|synapse|
|extracellular matrix organization|
|sulfur compound metabolic process|
|glycoprotein metabolic process|
|extracellular structure organization|
|positive regulation of cell adhesion|
|cell junction|
|cell morphogenesis involved in differentiation|
|regulation of cell adhesion|
|calcium ion binding|
|cell morphogenesis|
|cellular component morphogenesis|
|peptidyl-amino acid modification|
|cell adhesion|
|biological adhesion|
|animal organ morphogenesis|
|cell migration|
|oxoacid metabolic process|
|organic acid metabolic process|
|carbohydrate derivative metabolic process|
|localization of cell|
|cell motility|
|locomotion|
|movement of cell or subcellular component|
|cell development|
|small molecule metabolic process|
|tissue development|
</modal>
\\

 === CRISPR Data ===
<button type='default' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='default' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
No hits were found.
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
No correlation found to any other genes in chemogenomics.
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 0/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|0/1|
|909776.0|0/1|
|bile duct|0/28|
|blood|0/28|
|bone|0/26|
|breast|0/33|
|central nervous system|0/56|
|cervix|0/4|
|colorectal|0/17|
|esophagus|0/13|
|fibroblast|0/1|
|gastric|0/16|
|kidney|0/21|
|liver|0/20|
|lung|0/75|
|lymphocyte|0/16|
|ovary|0/26|
|pancreas|0/24|
|peripheral nervous system|0/16|
|plasma cell|0/15|
|prostate|0/1|
|skin|0/24|
|soft tissue|0/9|
|thyroid|0/2|
|upper aerodigestive|0/22|
|urinary tract|0/29|
|uterus|0/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 14524
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: -0.77 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='EGFLAM Expression in NALM6 Cells: -0.77'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>