======= F8A3 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: F8A3
  * **<color #00a2e8>Official Name</color>**: coagulation factor VIII associated 3
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=474384|474384]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/P23610|P23610]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=F8A3&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20F8A3|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**:  N/A

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**:  Not known. Possible housekeeping role.

<button type='default' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='default' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
No Pfam Domain information is available for this gene.
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
No GO term information is available for this gene.
</modal>
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 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp470|Chloroquine 32μM R08 exp470]]|-2.5|
|[[:results:exp454|Bafilomycin-A1 0.009μM R08 exp454]]|-2.43|
|[[:results:exp68|Clomiphene 4.4μM R02 exp68]]|-2.4|
|[[:results:exp169|BH1 1μM R04 exp169]]|-2.15|
|[[:results:exp434|Vemurafenib 6.6μM R08 exp434]]|-1.93|
|[[:results:exp175|3-Bromopyruvate 7μM R04 exp175]]|1.78|
|[[:results:exp242|Radicicol 0.16μM R05 exp242]]|1.91|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:h:htt|HTT]]|0.602|
|[[:human genes:h:hgc6.3|HGC6.3]]|0.402|
|[[:human genes:t:tbc1d23|TBC1D23]]|0.402|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: N/A
^Tissue^Fraction Of Cell Lines Where Essential^
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 3108
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 3.52 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='F8A3 Expression in NALM6 Cells: 3.52'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>