======= FAT3 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: FAT3
  * **<color #00a2e8>Official Name</color>**: FAT atypical cadherin 3
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=120114|120114]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q8TDW7|Q8TDW7]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=FAT3&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20FAT3|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: [[https://omim.org/entry/612483|Open OMIM]]

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**:  May play a role in the interactions between neurites derived from specific subsets of neurons during development. {ECO:0000250}.

<button type='primary' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
|Laminin G 1|
|Cadherin|
|Laminin G 2|
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|homophilic cell adhesion via plasma membrane adhesion molecules|
|cell-cell adhesion via plasma-membrane adhesion molecules|
|cell-cell adhesion|
|calcium ion binding|
|cell adhesion|
|biological adhesion|
</modal>
\\

 === CRISPR Data ===
<button type='default' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='default' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
No hits were found.
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
No correlation found to any other genes in chemogenomics.
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: N/A
^Tissue^Fraction Of Cell Lines Where Essential^
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 18092
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 1.68 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='FAT3 Expression in NALM6 Cells: 1.68'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>