======= FUT9 ======= == Gene Information == * **Official Symbol**: FUT9 * **Official Name**: fucosyltransferase 9 * **Aliases and Previous Symbols**: N/A * **Entrez ID**: [[https://www.ncbi.nlm.nih.gov/gene/?term=10690|10690]] * **UniProt**: [[https://www.uniprot.org/uniprot/Q9Y231|Q9Y231]] * **Interactions**: [[https://thebiogrid.org/search.php?search=FUT9&organism=9606|BioGRID]] * **PubMed articles**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20FUT9|Open PubMed]] * **OMIM**: [[https://omim.org/entry/606865|Open OMIM]] == Function Summary == * **Entrez Summary**: N/A * **UniProt Summary**: Transfers a fucose to lacto-N-neotetraose but not to either alpha2,3-sialyl lacto-N-neotetraose or lacto-N-tetraose. Can catalyze the last step in the biosynthesis of Lewis antigen, the addition of a fucose to precursor polysaccharides. {ECO:0000269|PubMed:10386598}. |Glyco transf 10| |alpha-(1->3)-fucosyltransferase activity| |L-fucose metabolic process| |fucose catabolic process| |fucosyltransferase activity| |L-fucose catabolic process| |fucose metabolic process| |fucosylation| |hexose catabolic process| |monosaccharide catabolic process| |Golgi cisterna membrane| |carbohydrate catabolic process| |hexose metabolic process| |monosaccharide metabolic process| |macromolecule glycosylation| |protein glycosylation| |glycosylation| |glycoprotein biosynthetic process| |glycoprotein metabolic process| |small molecule catabolic process| |carbohydrate metabolic process| |carbohydrate derivative biosynthetic process| |Golgi apparatus| |carbohydrate derivative metabolic process| |organonitrogen compound biosynthetic process| |cellular macromolecule biosynthetic process| |small molecule metabolic process| |macromolecule biosynthetic process| |organic substance catabolic process| \\ === CRISPR Data === No hits were found. No correlation found to any other genes in chemogenomics. Global Fraction of Cell Lines Where Essential: 0/739 ^Tissue^Fraction Of Cell Lines Where Essential^ |1290807.0|0/1| |909776.0|0/1| |bile duct|0/28| |blood|0/28| |bone|0/26| |breast|0/33| |central nervous system|0/56| |cervix|0/4| |colorectal|0/17| |esophagus|0/13| |fibroblast|0/1| |gastric|0/16| |kidney|0/21| |liver|0/20| |lung|0/75| |lymphocyte|0/16| |ovary|0/26| |pancreas|0/24| |peripheral nervous system|0/16| |plasma cell|0/15| |prostate|0/1| |skin|0/24| |soft tissue|0/9| |thyroid|0/2| |upper aerodigestive|0/22| |urinary tract|0/29| |uterus|0/5| == Essentiality in NALM6 == * **Essentiality Rank**: 13014 * **Expression level (log2 read counts)**: 1.15 {{:chemogenomics:nalm6 dist.png?nolink |}}