======= GOLGA6L6 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: GOLGA6L6
  * **<color #00a2e8>Official Name</color>**: golgin A6 family like 6
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=727832|727832]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/A8MZA4|A8MZA4]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=GOLGA6L6&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20GOLGA6L6|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**:  N/A

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='default' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='default' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
No Pfam Domain information is available for this gene.
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
No GO term information is available for this gene.
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp440|Aphidicolin 0.4μM R08 exp440]]|-2.18|
|[[:results:exp2|5-Fluorouracil 20μM R00 exp2]]|-2.11|
|[[:results:exp448|Ammonium tetrathiomolybdate 10μM R08 exp448]]|-2.11|
|[[:results:exp28|Pimelic-diphenylamide-106 5μM R00 exp28]]|-1.98|
|[[:results:exp4|Actinomycin-D 0.01μM R00 exp4]]|-1.87|
|[[:results:exp478|Doxorubicin 0.02μM R08 exp478]]|-1.84|
|[[:results:exp34|Rotenone 20μM R00 exp34]]|-1.78|
|[[:results:exp435|JQ1 0.8μM R08 exp435]]|-1.76|
|[[:results:exp484|GSK-J5 1.5μM R08 exp484]]|1.72|
|[[:results:exp405|Tenofovir 10μM R07 exp405]]|1.72|
|[[:results:exp46|HMS-I1 1μM R01 exp46]]|1.75|
|[[:results:exp89|Vemurafenib 6.6μM R02 exp89]]|1.77|
|[[:results:exp437|Ethanol 0.003 R08 exp437]]|1.79|
|[[:results:exp58|UM131593 0.1μM R01 exp58]]|1.84|
|[[:results:exp331|A-769662 20μM R07 exp331]]|1.97|
|[[:results:exp280|Daidzin 10μM R06 exp280]]|2.04|
|[[:results:exp59|UMK57 1μM R01 exp59]]|2.1|
|[[:results:exp496|Lead acetate 990μM R08 exp496]]|2.36|
|[[:results:exp223|Cabazitaxel 0.001μM R05 exp223]]|2.48|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:t:tceb3c|TCEB3C]]|0.517|
|[[:human genes:t:tceb3cl2|TCEB3CL2]]|0.517|
|[[:human genes:d:ddtl|DDTL]]|0.514|
|[[:human genes:t:tceb3cl|TCEB3CL]]|0.504|
|[[:human genes:p:psma6|PSMA6]]|0.498|
|[[:human genes:p:psmb1|PSMB1]]|0.494|
|[[:human genes:c:cactin|CACTIN]]|0.492|
|[[:human genes:p:psmb4|PSMB4]]|0.487|
|[[:human genes:h:hivep3|HIVEP3]]|0.487|
|[[:human genes:o:orc1|ORC1]]|0.486|
|[[:human genes:c:chd4|CHD4]]|0.483|
|[[:human genes:p:polr2d|POLR2D]]|0.479|
|[[:human genes:s:supt6h|SUPT6H]]|0.479|
|[[:human genes:g:golga8o|GOLGA8O]]|0.478|
|[[:human genes:d:dhfr|DHFR]]|0.477|
|[[:human genes:l:lrr1|LRR1]]|0.477|
|[[:human genes:s:sf3a1|SF3A1]]|0.476|
|[[:human genes:n:nup205|NUP205]]|0.476|
|[[:human genes:m:myb|MYB]]|0.472|
|[[:human genes:p:paf1|PAF1]]|0.468|
|[[:human genes:t:tp53tg3b|TP53TG3B]]|0.468|
|[[:human genes:t:tp53tg3|TP53TG3]]|0.468|
|[[:human genes:t:tp53tg3c|TP53TG3C]]|0.467|
|[[:human genes:m:mt1e|MT1E]]|0.465|
|[[:human genes:t:taf1|TAF1]]|0.465|
|[[:human genes:r:rpl35|RPL35]]|0.463|
|[[:human genes:n:nupl1|NUPL1]]|0.46|
|[[:human genes:k:kctd17|KCTD17]]|0.459|
|[[:human genes:h:hap1|HAP1]]|0.458|
|[[:human genes:p:psma7|PSMA7]]|0.456|
|[[:human genes:p:pan2|PAN2]]|0.455|
|[[:human genes:s:supt5h|SUPT5H]]|0.449|
|[[:human genes:c:cep192|CEP192]]|0.449|
|[[:human genes:c:copg1|COPG1]]|0.446|
|[[:human genes:n:npipb5|NPIPB5]]|0.445|
|[[:human genes:w:wdr75|WDR75]]|0.445|
|[[:human genes:t:tbc1d3g|TBC1D3G]]|0.443|
|[[:human genes:p:psmc6|PSMC6]]|0.442|
|[[:human genes:h:hist1h2be|HIST1H2BE]]|0.441|
|[[:human genes:r:rps9|RPS9]]|0.44|
|[[:human genes:t:tspy1|TSPY1]]|0.44|
|[[:human genes:r:rad21|RAD21]]|0.439|
|[[:human genes:c:ctage4|CTAGE4]]|0.439|
|[[:human genes:p:psmc2|PSMC2]]|0.438|
|[[:human genes:r:rad51|RAD51]]|0.437|
|[[:human genes:r:rps11|RPS11]]|0.437|
|[[:human genes:r:rps2|RPS2]]|0.437|
|[[:human genes:c:cbwd3|CBWD3]]|0.436|
|[[:human genes:r:rps12|RPS12]]|0.436|
|[[:human genes:e:esf1|ESF1]]|0.435|
|[[:human genes:s:ssh2|SSH2]]|0.433|
|[[:human genes:u:upf1|UPF1]]|0.431|
|[[:human genes:c:chmp4b|CHMP4B]]|0.43|
|[[:human genes:t:tp53tg3d|TP53TG3D]]|0.429|
|[[:human genes:p:pola1|POLA1]]|0.428|
|[[:human genes:b:bysl|BYSL]]|0.427|
|[[:human genes:t:tbc1d3c|TBC1D3C]]|0.427|
|[[:human genes:t:twistnb|TWISTNB]]|0.426|
|[[:human genes:p:psmd14|PSMD14]]|0.426|
|[[:human genes:c:cbwd5|CBWD5]]|0.423|
|[[:human genes:t:tbc1d3h|TBC1D3H]]|0.423|
|[[:human genes:u:uqcrh|UQCRH]]|0.422|
|[[:human genes:r:rps7|RPS7]]|0.422|
|[[:human genes:d:ddx56|DDX56]]|0.421|
|[[:human genes:a:aatf|AATF]]|0.42|
|[[:human genes:p:psmd1|PSMD1]]|0.419|
|[[:human genes:s:sf3a3|SF3A3]]|0.419|
|[[:human genes:c:c1qtnf9b|C1QTNF9B]]|0.418|
|[[:human genes:l:lad1|LAD1]]|0.418|
|[[:human genes:p:pan3|PAN3]]|0.418|
|[[:human genes:p:psmc1|PSMC1]]|0.417|
|[[:human genes:p:psmc4|PSMC4]]|0.416|
|[[:human genes:r:rrp7a|RRP7A]]|0.415|
|[[:human genes:c:cln6|CLN6]]|0.415|
|[[:human genes:a:akirin2|AKIRIN2]]|0.414|
|[[:human genes:o:osbp|OSBP]]|0.413|
|[[:human genes:n:nup54|NUP54]]|0.413|
|[[:human genes:n:nbpf10|NBPF10]]|0.412|
|[[:human genes:c:cdc6|CDC6]]|0.412|
|[[:human genes:i:ik|IK]]|0.411|
|[[:human genes:p:plk1|PLK1]]|0.411|
|[[:human genes:r:rnf121|RNF121]]|0.409|
|[[:human genes:s:syt9|SYT9]]|0.408|
|[[:human genes:a:ankle2|ANKLE2]]|0.408|
|[[:human genes:c:chmp2a|CHMP2A]]|0.408|
|[[:human genes:n:nup62|NUP62]]|0.407|
|[[:human genes:p:psmd2|PSMD2]]|0.407|
|[[:human genes:f:fam25b|FAM25B]]|0.406|
|[[:human genes:c:ccdc116|CCDC116]]|0.406|
|[[:human genes:p:polr2h|POLR2H]]|0.406|
|[[:human genes:o:orc6|ORC6]]|0.406|
|[[:human genes:z:znf106|ZNF106]]|0.406|
|[[:human genes:h:hinfp|HINFP]]|0.405|
|[[:human genes:s:slc6a17|SLC6A17]]|0.404|
|[[:human genes:c:ctage9|CTAGE9]]|0.401|
|[[:human genes:n:nop16|NOP16]]|0.401|
|[[:human genes:h:hist2h3d|HIST2H3D]]|0.401|
|[[:human genes:d:dtl|DTL]]|0.401|
|[[:human genes:e:exosc8|EXOSC8]]|0.4|
|[[:human genes:p:psap|PSAP]]|0.4|
|[[:human genes:g:golga8j|GOLGA8J]]|0.4|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 0/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|0/1|
|909776.0|0/1|
|bile duct|0/28|
|blood|0/28|
|bone|0/26|
|breast|0/33|
|central nervous system|0/56|
|cervix|0/4|
|colorectal|0/17|
|esophagus|0/13|
|fibroblast|0/1|
|gastric|0/16|
|kidney|0/21|
|liver|0/20|
|lung|0/75|
|lymphocyte|0/16|
|ovary|0/26|
|pancreas|0/24|
|peripheral nervous system|0/16|
|plasma cell|0/15|
|prostate|0/1|
|skin|0/24|
|soft tissue|0/9|
|thyroid|0/2|
|upper aerodigestive|0/22|
|urinary tract|0/29|
|uterus|0/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 1384
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 0.8 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='GOLGA6L6 Expression in NALM6 Cells: 0.8'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>