======= GTPBP6 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: GTPBP6
  * **<color #00a2e8>Official Name</color>**: GTP binding protein 6 (putative)
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=8225|8225]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/O43824|O43824]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=GTPBP6&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20GTPBP6|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: [[https://omim.org/entry/300124|Open OMIM]]

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**:  This gene encodes a GTP binding protein and is located in the pseudoautosomal region (PAR) at the end of the short arms of the X and Y chromosomes. [provided by RefSeq, Nov 2011]. 
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='default' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
No Pfam Domain information is available for this gene.
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|ribosome binding|
|GTP binding|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp124|GSK343 3μM R03 exp124]]|-1.92|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:n:nars2|NARS2]]|0.546|
|[[:human genes:p:pet112|PET112]]|0.54|
|[[:human genes:m:mtrf1l|MTRF1L]]|0.532|
|[[:human genes:l:lars2|LARS2]]|0.532|
|[[:human genes:a:acad9|ACAD9]]|0.52|
|[[:human genes:m:mrps10|MRPS10]]|0.508|
|[[:human genes:f:fastkd2|FASTKD2]]|0.507|
|[[:human genes:m:mettl17|METTL17]]|0.506|
|[[:human genes:g:gtpbp10|GTPBP10]]|0.504|
|[[:human genes:n:ndufs2|NDUFS2]]|0.503|
|[[:human genes:n:ndufa3|NDUFA3]]|0.499|
|[[:human genes:p:pars2|PARS2]]|0.493|
|[[:human genes:m:mrpl21|MRPL21]]|0.489|
|[[:human genes:d:dap3|DAP3]]|0.489|
|[[:human genes:y:yars2|YARS2]]|0.489|
|[[:human genes:e:ears2|EARS2]]|0.489|
|[[:human genes:n:ndufb11|NDUFB11]]|0.489|
|[[:human genes:n:ndufa1|NDUFA1]]|0.486|
|[[:human genes:m:mrp63|MRP63]]|0.485|
|[[:human genes:c:cars2|CARS2]]|0.482|
|[[:human genes:n:ndufaf7|NDUFAF7]]|0.479|
|[[:human genes:n:ndufc1|NDUFC1]]|0.478|
|[[:human genes:q:qrsl1|QRSL1]]|0.478|
|[[:human genes:s:selrc1|SELRC1]]|0.475|
|[[:human genes:t:tfb1m|TFB1M]]|0.475|
|[[:human genes:n:ndufb9|NDUFB9]]|0.471|
|[[:human genes:m:mrps21|MRPS21]]|0.469|
|[[:human genes:m:mrpl12|MRPL12]]|0.468|
|[[:human genes:w:wars2|WARS2]]|0.467|
|[[:human genes:r:rars2|RARS2]]|0.465|
|[[:human genes:i:iba57|IBA57]]|0.465|
|[[:human genes:m:mtif2|MTIF2]]|0.464|
|[[:human genes:n:ndufs5|NDUFS5]]|0.463|
|[[:human genes:n:nsun4|NSUN4]]|0.462|
|[[:human genes:r:rpusd3|RPUSD3]]|0.46|
|[[:human genes:m:mrps34|MRPS34]]|0.459|
|[[:human genes:g:gfm1|GFM1]]|0.457|
|[[:human genes:n:nubpl|NUBPL]]|0.455|
|[[:human genes:l:lrpprc|LRPPRC]]|0.455|
|[[:human genes:n:ndufv1|NDUFV1]]|0.454|
|[[:human genes:n:ndufc2|NDUFC2]]|0.453|
|[[:human genes:v:vars2|VARS2]]|0.452|
|[[:human genes:m:mtg1|MTG1]]|0.451|
|[[:human genes:m:mrps27|MRPS27]]|0.447|
|[[:human genes:t:tars2|TARS2]]|0.445|
|[[:human genes:r:rbfa|RBFA]]|0.445|
|[[:human genes:e:eral1|ERAL1]]|0.444|
|[[:human genes:p:polrmt|POLRMT]]|0.443|
|[[:human genes:t:trub2|TRUB2]]|0.443|
|[[:human genes:w:wbscr16|WBSCR16]]|0.442|
|[[:human genes:d:ddx28|DDX28]]|0.441|
|[[:human genes:n:ndufaf5|NDUFAF5]]|0.441|
|[[:human genes:m:mrps6|MRPS6]]|0.439|
|[[:human genes:t:timmdc1|TIMMDC1]]|0.439|
|[[:human genes:n:ndufa11|NDUFA11]]|0.438|
|[[:human genes:c:coq3|COQ3]]|0.438|
|[[:human genes:m:mrps25|MRPS25]]|0.438|
|[[:human genes:m:mrps16|MRPS16]]|0.437|
|[[:human genes:m:mrps18a|MRPS18A]]|0.435|
|[[:human genes:p:pet117|PET117]]|0.434|
|[[:human genes:f:ftsj2|FTSJ2]]|0.434|
|[[:human genes:r:rtn4ip1|RTN4IP1]]|0.434|
|[[:human genes:p:pnpt1|PNPT1]]|0.429|
|[[:human genes:g:gfm2|GFM2]]|0.429|
|[[:human genes:a:aars2|AARS2]]|0.429|
|[[:human genes:c:chchd1|CHCHD1]]|0.426|
|[[:human genes:c:coq7|COQ7]]|0.426|
|[[:human genes:g:grsf1|GRSF1]]|0.425|
|[[:human genes:s:sco2|SCO2]]|0.424|
|[[:human genes:g:glrx5|GLRX5]]|0.424|
|[[:human genes:g:gtpbp8|GTPBP8]]|0.423|
|[[:human genes:m:mterfd1|MTERFD1]]|0.423|
|[[:human genes:r:rmnd1|RMND1]]|0.423|
|[[:human genes:m:mrpl45|MRPL45]]|0.422|
|[[:human genes:m:mrps22|MRPS22]]|0.418|
|[[:human genes:n:ndufaf6|NDUFAF6]]|0.418|
|[[:human genes:t:tfam|TFAM]]|0.418|
|[[:human genes:n:ndufaf3|NDUFAF3]]|0.417|
|[[:human genes:c:coa3|COA3]]|0.416|
|[[:human genes:p:ptcd3|PTCD3]]|0.416|
|[[:human genes:h:hmgxb3|HMGXB3]]|0.415|
|[[:human genes:m:mrpl53|MRPL53]]|0.415|
|[[:human genes:p:pde12|PDE12]]|0.415|
|[[:human genes:n:ndufa2|NDUFA2]]|0.415|
|[[:human genes:f:fars2|FARS2]]|0.414|
|[[:human genes:p:polg2|POLG2]]|0.413|
|[[:human genes:x:xpnpep3|XPNPEP3]]|0.412|
|[[:human genes:m:mto1|MTO1]]|0.412|
|[[:human genes:h:hsd17b10|HSD17B10]]|0.411|
|[[:human genes:m:mrps35|MRPS35]]|0.411|
|[[:human genes:r:rpusd4|RPUSD4]]|0.41|
|[[:human genes:t:tomm7|TOMM7]]|0.41|
|[[:human genes:h:hars2|HARS2]]|0.41|
|[[:human genes:m:mrpl3|MRPL3]]|0.407|
|[[:human genes:n:ndufb10|NDUFB10]]|0.407|
|[[:human genes:m:mtg2|MTG2]]|0.405|
|[[:human genes:m:mrpl18|MRPL18]]|0.405|
|[[:human genes:n:ndufb7|NDUFB7]]|0.405|
|[[:human genes:c:cox20|COX20]]|0.404|
|[[:human genes:m:mtif3|MTIF3]]|0.403|
|[[:human genes:m:mrpl13|MRPL13]]|0.402|
|[[:human genes:c:clpp|CLPP]]|0.401|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: N/A
^Tissue^Fraction Of Cell Lines Where Essential^
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 1408
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 6.39 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='GTPBP6 Expression in NALM6 Cells: 6.39'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>