======= MRPL55 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: MRPL55
  * **<color #00a2e8>Official Name</color>**: mitochondrial ribosomal protein L55
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=128308|128308]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q7Z7F7|Q7Z7F7]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=MRPL55&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20MRPL55|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: [[https://omim.org/entry/611859|Open OMIM]]

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='primary' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
|Mitoc L55|
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|mitochondrial large ribosomal subunit|
|mitochondrial translational elongation|
|mitochondrial translational termination|
|translational termination|
|mitochondrial translation|
|translational elongation|
|cellular protein complex disassembly|
|mitochondrial gene expression|
|structural constituent of ribosome|
|protein-containing complex disassembly|
|translation|
|mitochondrial inner membrane|
|cellular component disassembly|
|peptide biosynthetic process|
|amide biosynthetic process|
|peptide metabolic process|
|cellular amide metabolic process|
|mitochondrion|
|organonitrogen compound biosynthetic process|
|cellular nitrogen compound biosynthetic process|
|cellular macromolecule biosynthetic process|
|macromolecule biosynthetic process|
|protein-containing complex subunit organization|
|gene expression|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp214|2-Deoxy-D-glucose 800μM R05 exp214]]|-2.36|
|[[:results:exp219|A-395N 10μM R05 exp219]]|-1.93|
|[[:results:exp539|42°C R08 exp539]]|1.86|
|[[:results:exp128|GSK591 2.6μM R03 exp128]]|2.04|
|[[:results:exp441|GSK-J4 1.5μM R08 exp441]]|2.3|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:m:mrps34|MRPS34]]|0.613|
|[[:human genes:h:hsd17b10|HSD17B10]]|0.609|
|[[:human genes:m:mrps5|MRPS5]]|0.609|
|[[:human genes:m:mtpap|MTPAP]]|0.591|
|[[:human genes:m:mrpl21|MRPL21]]|0.579|
|[[:human genes:r:rpusd4|RPUSD4]]|0.573|
|[[:human genes:m:mrpl23|MRPL23]]|0.567|
|[[:human genes:m:mrps21|MRPS21]]|0.56|
|[[:human genes:m:mrps18a|MRPS18A]]|0.555|
|[[:human genes:t:trub2|TRUB2]]|0.554|
|[[:human genes:v:vars2|VARS2]]|0.55|
|[[:human genes:c:c12orf65|C12orf65]]|0.546|
|[[:human genes:k:kiaa0391|KIAA0391]]|0.545|
|[[:human genes:s:sars2|SARS2]]|0.544|
|[[:human genes:m:mrpl53|MRPL53]]|0.544|
|[[:human genes:m:mrps2|MRPS2]]|0.543|
|[[:human genes:y:yars2|YARS2]]|0.533|
|[[:human genes:s:supv3l1|SUPV3L1]]|0.532|
|[[:human genes:c:c17orf89|C17orf89]]|0.532|
|[[:human genes:m:mrps12|MRPS12]]|0.531|
|[[:human genes:m:mrps9|MRPS9]]|0.529|
|[[:human genes:t:tars2|TARS2]]|0.527|
|[[:human genes:g:gfm1|GFM1]]|0.527|
|[[:human genes:f:fastkd5|FASTKD5]]|0.526|
|[[:human genes:g:gtpbp10|GTPBP10]]|0.523|
|[[:human genes:s:selrc1|SELRC1]]|0.523|
|[[:human genes:m:mrp63|MRP63]]|0.523|
|[[:human genes:g:gfm2|GFM2]]|0.518|
|[[:human genes:c:cox6c|COX6C]]|0.517|
|[[:human genes:t:tefm|TEFM]]|0.516|
|[[:human genes:c:c10orf2|C10orf2]]|0.515|
|[[:human genes:c:coq2|COQ2]]|0.515|
|[[:human genes:m:mrps6|MRPS6]]|0.515|
|[[:human genes:m:mrpl12|MRPL12]]|0.514|
|[[:human genes:q:qrsl1|QRSL1]]|0.514|
|[[:human genes:m:mrps24|MRPS24]]|0.512|
|[[:human genes:m:mtg2|MTG2]]|0.511|
|[[:human genes:n:ndufb11|NDUFB11]]|0.508|
|[[:human genes:m:mrps14|MRPS14]]|0.505|
|[[:human genes:m:mrps26|MRPS26]]|0.501|
|[[:human genes:m:mrpl47|MRPL47]]|0.499|
|[[:human genes:c:cox15|COX15]]|0.498|
|[[:human genes:f:fars2|FARS2]]|0.498|
|[[:human genes:m:mrps16|MRPS16]]|0.493|
|[[:human genes:d:dars2|DARS2]]|0.492|
|[[:human genes:m:mrps25|MRPS25]]|0.49|
|[[:human genes:s:sco2|SCO2]]|0.49|
|[[:human genes:n:ndufa3|NDUFA3]]|0.488|
|[[:human genes:t:tufm|TUFM]]|0.487|
|[[:human genes:e:ears2|EARS2]]|0.487|
|[[:human genes:m:mrps10|MRPS10]]|0.486|
|[[:human genes:m:mrps35|MRPS35]]|0.484|
|[[:human genes:r:rars2|RARS2]]|0.483|
|[[:human genes:p:pdss1|PDSS1]]|0.477|
|[[:human genes:m:mrpl15|MRPL15]]|0.472|
|[[:human genes:n:ndufa2|NDUFA2]]|0.472|
|[[:human genes:m:mtg1|MTG1]]|0.471|
|[[:human genes:c:cox16|COX16]]|0.47|
|[[:human genes:b:bcs1l|BCS1L]]|0.47|
|[[:human genes:f:ftsj2|FTSJ2]]|0.468|
|[[:human genes:p:pars2|PARS2]]|0.465|
|[[:human genes:w:wbscr16|WBSCR16]]|0.461|
|[[:human genes:d:dap3|DAP3]]|0.46|
|[[:human genes:m:mrpl18|MRPL18]]|0.458|
|[[:human genes:m:mrps23|MRPS23]]|0.452|
|[[:human genes:n:nars2|NARS2]]|0.451|
|[[:human genes:c:coa3|COA3]]|0.45|
|[[:human genes:r:rbfa|RBFA]]|0.45|
|[[:human genes:m:mrpl44|MRPL44]]|0.448|
|[[:human genes:p:pet112|PET112]]|0.448|
|[[:human genes:l:lrpprc|LRPPRC]]|0.444|
|[[:human genes:m:mrpl46|MRPL46]]|0.443|
|[[:human genes:m:mrpl34|MRPL34]]|0.443|
|[[:human genes:m:mars2|MARS2]]|0.443|
|[[:human genes:t:tmem242|TMEM242]]|0.443|
|[[:human genes:m:mrps22|MRPS22]]|0.441|
|[[:human genes:r:rnaseh1|RNASEH1]]|0.44|
|[[:human genes:d:dhx30|DHX30]]|0.44|
|[[:human genes:e:ecsit|ECSIT]]|0.439|
|[[:human genes:m:mrps11|MRPS11]]|0.438|
|[[:human genes:u:uqcr10|UQCR10]]|0.437|
|[[:human genes:c:coa6|COA6]]|0.437|
|[[:human genes:m:mrpl20|MRPL20]]|0.436|
|[[:human genes:l:lars2|LARS2]]|0.435|
|[[:human genes:m:mrpl43|MRPL43]]|0.434|
|[[:human genes:m:mterfd2|MTERFD2]]|0.434|
|[[:human genes:c:cox6b1|COX6B1]]|0.434|
|[[:human genes:u:uqcrc2|UQCRC2]]|0.433|
|[[:human genes:n:ndufc2|NDUFC2]]|0.432|
|[[:human genes:m:mrpl4|MRPL4]]|0.432|
|[[:human genes:c:chchd1|CHCHD1]]|0.431|
|[[:human genes:n:ndufaf3|NDUFAF3]]|0.431|
|[[:human genes:t:tfam|TFAM]]|0.429|
|[[:human genes:h:hars2|HARS2]]|0.429|
|[[:human genes:p:pnpt1|PNPT1]]|0.428|
|[[:human genes:p:pet117|PET117]]|0.425|
|[[:human genes:c:cox17|COX17]]|0.424|
|[[:human genes:c:coq3|COQ3]]|0.424|
|[[:human genes:m:mtrf1l|MTRF1L]]|0.423|
|[[:human genes:m:mrpl17|MRPL17]]|0.423|
|[[:human genes:n:ndufaf7|NDUFAF7]]|0.422|
|[[:human genes:t:timm8b|TIMM8B]]|0.42|
|[[:human genes:m:mrpl42|MRPL42]]|0.42|
|[[:human genes:n:ndufb2|NDUFB2]]|0.419|
|[[:human genes:a:atp5d|ATP5D]]|0.418|
|[[:human genes:a:aars2|AARS2]]|0.418|
|[[:human genes:m:mrpl3|MRPL3]]|0.414|
|[[:human genes:g:gatc|GATC]]|0.411|
|[[:human genes:m:mrpl49|MRPL49]]|0.41|
|[[:human genes:m:mrpl45|MRPL45]]|0.41|
|[[:human genes:u:uqcrfs1|UQCRFS1]]|0.409|
|[[:human genes:m:mcat|MCAT]]|0.408|
|[[:human genes:m:mrpl13|MRPL13]]|0.408|
|[[:human genes:m:mrpl2|MRPL2]]|0.407|
|[[:human genes:n:ndufs7|NDUFS7]]|0.407|
|[[:human genes:r:rpusd3|RPUSD3]]|0.405|
|[[:human genes:c:coa5|COA5]]|0.405|
|[[:human genes:t:tomm40|TOMM40]]|0.404|
|[[:human genes:m:mrpl11|MRPL11]]|0.404|
|[[:human genes:m:mrpl35|MRPL35]]|0.402|
|[[:human genes:c:chchd4|CHCHD4]]|0.402|
|[[:human genes:n:ndufb3|NDUFB3]]|0.402|
|[[:human genes:m:mettl17|METTL17]]|0.402|
|[[:human genes:m:mrpl52|MRPL52]]|0.401|
|[[:human genes:m:mrpl36|MRPL36]]|0.401|
|[[:human genes:h:hmgxb3|HMGXB3]]|0.401|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 60/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|0/1|
|909776.0|0/1|
|bile duct|1/28|
|blood|3/28|
|bone|2/26|
|breast|3/33|
|central nervous system|3/56|
|cervix|1/4|
|colorectal|2/17|
|esophagus|2/13|
|fibroblast|0/1|
|gastric|0/16|
|kidney|3/21|
|liver|2/20|
|lung|10/75|
|lymphocyte|0/16|
|ovary|0/26|
|pancreas|2/24|
|peripheral nervous system|1/16|
|plasma cell|1/15|
|prostate|0/1|
|skin|2/24|
|soft tissue|2/9|
|thyroid|0/2|
|upper aerodigestive|5/22|
|urinary tract|1/29|
|uterus|0/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 1661
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 4.4 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='MRPL55 Expression in NALM6 Cells: 4.4'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>