======= MRPS24 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: MRPS24
  * **<color #00a2e8>Official Name</color>**: mitochondrial ribosomal protein S24
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=64951|64951]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q96EL2|Q96EL2]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=MRPS24&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20MRPS24|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: [[https://omim.org/entry/611986|Open OMIM]]

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='default' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
No Pfam Domain information is available for this gene.
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|mitochondrial small ribosomal subunit|
|mitochondrial translational elongation|
|mitochondrial translational termination|
|translational termination|
|mitochondrial translation|
|translational elongation|
|cellular protein complex disassembly|
|mitochondrial gene expression|
|structural constituent of ribosome|
|protein-containing complex disassembly|
|translation|
|mitochondrial inner membrane|
|cellular component disassembly|
|peptide biosynthetic process|
|amide biosynthetic process|
|peptide metabolic process|
|cellular amide metabolic process|
|RNA binding|
|organonitrogen compound biosynthetic process|
|cellular nitrogen compound biosynthetic process|
|cellular macromolecule biosynthetic process|
|macromolecule biosynthetic process|
|protein-containing complex subunit organization|
|gene expression|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp441|GSK-J4 1.5μM R08 exp441]]|1.73|
|[[:results:exp503|Mitomycin-C 0.06μM R08 exp503]]|1.76|
|[[:results:exp94|Nocodazole 0.1μM R03 exp94]]|1.76|
|[[:results:exp208|Vinblastine 0.015μM R05 exp208]]|1.84|
|[[:results:exp529|Thimerosal 0.85μM R08 exp529]]|2.07|
|[[:results:exp492|iCRT14 30μM R08 exp492]]|2.22|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:m:mrpl53|MRPL53]]|0.635|
|[[:human genes:h:hsd17b10|HSD17B10]]|0.62|
|[[:human genes:s:selrc1|SELRC1]]|0.61|
|[[:human genes:y:yars2|YARS2]]|0.608|
|[[:human genes:m:mrps34|MRPS34]]|0.608|
|[[:human genes:v:vars2|VARS2]]|0.604|
|[[:human genes:t:tars2|TARS2]]|0.602|
|[[:human genes:e:ears2|EARS2]]|0.6|
|[[:human genes:r:rpusd4|RPUSD4]]|0.599|
|[[:human genes:m:mrps16|MRPS16]]|0.584|
|[[:human genes:m:mrpl23|MRPL23]]|0.584|
|[[:human genes:m:mrp63|MRP63]]|0.575|
|[[:human genes:c:cox16|COX16]]|0.574|
|[[:human genes:m:mrpl21|MRPL21]]|0.573|
|[[:human genes:m:mrps5|MRPS5]]|0.571|
|[[:human genes:f:fastkd5|FASTKD5]]|0.57|
|[[:human genes:s:sars2|SARS2]]|0.57|
|[[:human genes:m:mrps26|MRPS26]]|0.564|
|[[:human genes:m:mrps21|MRPS21]]|0.562|
|[[:human genes:p:pars2|PARS2]]|0.561|
|[[:human genes:m:mrpl47|MRPL47]]|0.559|
|[[:human genes:m:mrps18a|MRPS18A]]|0.559|
|[[:human genes:n:ndufa3|NDUFA3]]|0.55|
|[[:human genes:m:mrps2|MRPS2]]|0.548|
|[[:human genes:s:sco2|SCO2]]|0.548|
|[[:human genes:d:dap3|DAP3]]|0.547|
|[[:human genes:d:dars2|DARS2]]|0.544|
|[[:human genes:m:mrps25|MRPS25]]|0.543|
|[[:human genes:k:kiaa0391|KIAA0391]]|0.543|
|[[:human genes:l:lars2|LARS2]]|0.542|
|[[:human genes:n:nars2|NARS2]]|0.541|
|[[:human genes:m:mterfd2|MTERFD2]]|0.538|
|[[:human genes:m:mrps6|MRPS6]]|0.536|
|[[:human genes:c:cox7b|COX7B]]|0.534|
|[[:human genes:g:gfm1|GFM1]]|0.534|
|[[:human genes:s:supv3l1|SUPV3L1]]|0.528|
|[[:human genes:m:mtg2|MTG2]]|0.527|
|[[:human genes:m:mars2|MARS2]]|0.525|
|[[:human genes:f:ftsj2|FTSJ2]]|0.525|
|[[:human genes:m:mrps12|MRPS12]]|0.524|
|[[:human genes:c:c12orf65|C12orf65]]|0.524|
|[[:human genes:r:rnaseh1|RNASEH1]]|0.524|
|[[:human genes:c:coa3|COA3]]|0.523|
|[[:human genes:n:ndufaf7|NDUFAF7]]|0.522|
|[[:human genes:t:tefm|TEFM]]|0.521|
|[[:human genes:m:mrpl12|MRPL12]]|0.519|
|[[:human genes:q:qrsl1|QRSL1]]|0.518|
|[[:human genes:a:aars2|AARS2]]|0.518|
|[[:human genes:f:fars2|FARS2]]|0.516|
|[[:human genes:u:uqcr10|UQCR10]]|0.516|
|[[:human genes:m:mrps10|MRPS10]]|0.515|
|[[:human genes:h:hars2|HARS2]]|0.514|
|[[:human genes:b:bcs1l|BCS1L]]|0.514|
|[[:human genes:m:mrpl55|MRPL55]]|0.512|
|[[:human genes:m:mtrf1l|MTRF1L]]|0.51|
|[[:human genes:m:mrps9|MRPS9]]|0.509|
|[[:human genes:g:gatc|GATC]]|0.509|
|[[:human genes:c:coa6|COA6]]|0.508|
|[[:human genes:n:ndufb11|NDUFB11]]|0.508|
|[[:human genes:m:mrpl15|MRPL15]]|0.505|
|[[:human genes:g:gtpbp10|GTPBP10]]|0.503|
|[[:human genes:t:tufm|TUFM]]|0.502|
|[[:human genes:m:mrpl20|MRPL20]]|0.502|
|[[:human genes:g:gfm2|GFM2]]|0.501|
|[[:human genes:p:pet117|PET117]]|0.496|
|[[:human genes:r:rbfa|RBFA]]|0.495|
|[[:human genes:m:mrpl34|MRPL34]]|0.493|
|[[:human genes:m:mtpap|MTPAP]]|0.492|
|[[:human genes:r:rars2|RARS2]]|0.489|
|[[:human genes:m:mrpl44|MRPL44]]|0.489|
|[[:human genes:m:mettl17|METTL17]]|0.488|
|[[:human genes:m:mtif3|MTIF3]]|0.485|
|[[:human genes:c:cox6c|COX6C]]|0.483|
|[[:human genes:m:mrps14|MRPS14]]|0.483|
|[[:human genes:t:trub2|TRUB2]]|0.479|
|[[:human genes:c:cox11|COX11]]|0.474|
|[[:human genes:m:mrps17|MRPS17]]|0.473|
|[[:human genes:c:chchd4|CHCHD4]]|0.472|
|[[:human genes:w:wbscr16|WBSCR16]]|0.471|
|[[:human genes:d:dhrsx|DHRSX]]|0.471|
|[[:human genes:p:pet112|PET112]]|0.471|
|[[:human genes:p:pnpt1|PNPT1]]|0.469|
|[[:human genes:m:mrpl18|MRPL18]]|0.468|
|[[:human genes:c:c10orf2|C10orf2]]|0.468|
|[[:human genes:l:lrpprc|LRPPRC]]|0.464|
|[[:human genes:p:pdss1|PDSS1]]|0.464|
|[[:human genes:m:mrps23|MRPS23]]|0.464|
|[[:human genes:m:mrpl17|MRPL17]]|0.463|
|[[:human genes:c:c17orf89|C17orf89]]|0.463|
|[[:human genes:m:mrps35|MRPS35]]|0.462|
|[[:human genes:m:mrpl32|MRPL32]]|0.461|
|[[:human genes:p:polg2|POLG2]]|0.461|
|[[:human genes:c:coq2|COQ2]]|0.46|
|[[:human genes:m:mrps33|MRPS33]]|0.459|
|[[:human genes:c:coq3|COQ3]]|0.457|
|[[:human genes:n:ndufa2|NDUFA2]]|0.455|
|[[:human genes:m:mrpl45|MRPL45]]|0.455|
|[[:human genes:m:mrpl46|MRPL46]]|0.455|
|[[:human genes:m:mrpl4|MRPL4]]|0.452|
|[[:human genes:m:mrpl43|MRPL43]]|0.451|
|[[:human genes:m:mrpl3|MRPL3]]|0.449|
|[[:human genes:m:mrps7|MRPS7]]|0.448|
|[[:human genes:u:uqcrc2|UQCRC2]]|0.446|
|[[:human genes:c:cox17|COX17]]|0.445|
|[[:human genes:m:mrpl37|MRPL37]]|0.441|
|[[:human genes:n:ndufs2|NDUFS2]]|0.44|
|[[:human genes:c:cars2|CARS2]]|0.439|
|[[:human genes:m:mtg1|MTG1]]|0.439|
|[[:human genes:m:mrpl38|MRPL38]]|0.437|
|[[:human genes:c:chchd1|CHCHD1]]|0.436|
|[[:human genes:n:ndufb1|NDUFB1]]|0.434|
|[[:human genes:m:mrpl11|MRPL11]]|0.434|
|[[:human genes:a:alg8|ALG8]]|0.433|
|[[:human genes:p:polg|POLG]]|0.432|
|[[:human genes:m:mipep|MIPEP]]|0.432|
|[[:human genes:n:ndufaf3|NDUFAF3]]|0.431|
|[[:human genes:n:ndufs7|NDUFS7]]|0.431|
|[[:human genes:n:ndufv1|NDUFV1]]|0.429|
|[[:human genes:t:tbrg4|TBRG4]]|0.428|
|[[:human genes:m:mrpl2|MRPL2]]|0.427|
|[[:human genes:r:rnmtl1|RNMTL1]]|0.427|
|[[:human genes:m:mrps11|MRPS11]]|0.426|
|[[:human genes:a:aifm1|AIFM1]]|0.426|
|[[:human genes:a:alas1|ALAS1]]|0.423|
|[[:human genes:t:tomm20|TOMM20]]|0.421|
|[[:human genes:m:malsu1|MALSU1]]|0.421|
|[[:human genes:m:mrpl39|MRPL39]]|0.421|
|[[:human genes:p:pet100|PET100]]|0.42|
|[[:human genes:c:cox15|COX15]]|0.42|
|[[:human genes:m:mrpl41|MRPL41]]|0.419|
|[[:human genes:m:mrpl9|MRPL9]]|0.419|
|[[:human genes:c:cox6b1|COX6B1]]|0.419|
|[[:human genes:t:tomm40|TOMM40]]|0.414|
|[[:human genes:m:mrpl42|MRPL42]]|0.414|
|[[:human genes:r:rpusd3|RPUSD3]]|0.413|
|[[:human genes:c:coq6|COQ6]]|0.411|
|[[:human genes:t:tfam|TFAM]]|0.41|
|[[:human genes:n:ndufc2|NDUFC2]]|0.408|
|[[:human genes:m:minos1|MINOS1]]|0.406|
|[[:human genes:r:rpia|RPIA]]|0.405|
|[[:human genes:m:mrpl33|MRPL33]]|0.405|
|[[:human genes:m:mrps27|MRPS27]]|0.404|
|[[:human genes:c:coq4|COQ4]]|0.402|
|[[:human genes:s:slc25a26|SLC25A26]]|0.401|
|[[:human genes:e:elac2|ELAC2]]|0.401|
|[[:human genes:t:tomm6|TOMM6]]|0.4|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 113/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|0/1|
|909776.0|0/1|
|bile duct|4/28|
|blood|4/28|
|bone|4/26|
|breast|5/33|
|central nervous system|4/56|
|cervix|2/4|
|colorectal|4/17|
|esophagus|4/13|
|fibroblast|0/1|
|gastric|3/16|
|kidney|4/21|
|liver|6/20|
|lung|12/75|
|lymphocyte|3/16|
|ovary|0/26|
|pancreas|1/24|
|peripheral nervous system|1/16|
|plasma cell|4/15|
|prostate|0/1|
|skin|4/24|
|soft tissue|2/9|
|thyroid|0/2|
|upper aerodigestive|5/22|
|urinary tract|6/29|
|uterus|1/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 1262
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 4.8 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='MRPS24 Expression in NALM6 Cells: 4.8'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>