======= NBPF10 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: NBPF10
  * **<color #00a2e8>Official Name</color>**: NBPF member 10
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=100132406|100132406]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q6P3W6|Q6P3W6]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=NBPF10&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20NBPF10|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: [[https://omim.org/entry/614000|Open OMIM]]

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='primary' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
|DUF1220|
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|RNA binding|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp448|Ammonium tetrathiomolybdate 10μM R08 exp448]]|-1.73|
|[[:results:exp220|BAY-598 4μM R05 exp220]]|1.77|
|[[:results:exp376|Losmapimod 1μM R07 exp376]]|1.77|
|[[:results:exp331|A-769662 20μM R07 exp331]]|1.81|
|[[:results:exp278|CVT-10216 0.1μM R06 exp278]]|1.89|
|[[:results:exp81|Selumetinib 20μM R02 exp81]]|2.41|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:t:tbc1d3g|TBC1D3G]]|0.522|
|[[:human genes:p:prim1|PRIM1]]|0.515|
|[[:human genes:t:twistnb|TWISTNB]]|0.505|
|[[:human genes:m:med17|MED17]]|0.497|
|[[:human genes:c:cdc6|CDC6]]|0.492|
|[[:human genes:m:myo1h|MYO1H]]|0.491|
|[[:human genes:o:orc1|ORC1]]|0.49|
|[[:human genes:t:tbc1d3c|TBC1D3C]]|0.489|
|[[:human genes:a:akirin2|AKIRIN2]]|0.484|
|[[:human genes:c:cbwd3|CBWD3]]|0.484|
|[[:human genes:t:tfip11|TFIP11]]|0.484|
|[[:human genes:c:chmp2a|CHMP2A]]|0.48|
|[[:human genes:t:tbc1d3h|TBC1D3H]]|0.479|
|[[:human genes:s:supt6h|SUPT6H]]|0.476|
|[[:human genes:p:pola2|POLA2]]|0.476|
|[[:human genes:t:tbc1d3f|TBC1D3F]]|0.475|
|[[:human genes:t:tbc1d3|TBC1D3]]|0.474|
|[[:human genes:d:dnttip2|DNTTIP2]]|0.473|
|[[:human genes:c:cbwd6|CBWD6]]|0.472|
|[[:human genes:c:copb1|COPB1]]|0.471|
|[[:human genes:p:pcf11|PCF11]]|0.469|
|[[:human genes:r:rpl14|RPL14]]|0.469|
|[[:human genes:d:ddtl|DDTL]]|0.468|
|[[:human genes:t:tceb3cl2|TCEB3CL2]]|0.468|
|[[:human genes:c:cbwd5|CBWD5]]|0.467|
|[[:human genes:c:c14orf93|C14orf93]]|0.467|
|[[:human genes:t:ticrr|TICRR]]|0.467|
|[[:human genes:n:nupl1|NUPL1]]|0.466|
|[[:human genes:c:c1qtnf9b|C1QTNF9B]]|0.465|
|[[:human genes:z:zfand5|ZFAND5]]|0.463|
|[[:human genes:p:polr2a|POLR2A]]|0.46|
|[[:human genes:s:sf3a3|SF3A3]]|0.458|
|[[:human genes:p:psmd11|PSMD11]]|0.456|
|[[:human genes:r:rbbp5|RBBP5]]|0.454|
|[[:human genes:c:cactin|CACTIN]]|0.452|
|[[:human genes:n:nol10|NOL10]]|0.452|
|[[:human genes:p:paf1|PAF1]]|0.451|
|[[:human genes:h:hap1|HAP1]]|0.449|
|[[:human genes:c:chd4|CHD4]]|0.448|
|[[:human genes:m:mt1e|MT1E]]|0.445|
|[[:human genes:p:psmd1|PSMD1]]|0.443|
|[[:human genes:r:rrp15|RRP15]]|0.443|
|[[:human genes:c:cdc45|CDC45]]|0.443|
|[[:human genes:p:psma6|PSMA6]]|0.442|
|[[:human genes:u:upf1|UPF1]]|0.442|
|[[:human genes:t:tagln|TAGLN]]|0.441|
|[[:human genes:t:tceb3c|TCEB3C]]|0.44|
|[[:human genes:k:kctd17|KCTD17]]|0.44|
|[[:human genes:c:cdc73|CDC73]]|0.44|
|[[:human genes:s:ssh2|SSH2]]|0.438|
|[[:human genes:c:copg1|COPG1]]|0.438|
|[[:human genes:p:psmb2|PSMB2]]|0.438|
|[[:human genes:t:tbc1d3i|TBC1D3I]]|0.436|
|[[:human genes:o:orc6|ORC6]]|0.436|
|[[:human genes:t:tbc1d3k|TBC1D3K]]|0.436|
|[[:human genes:s:slc6a17|SLC6A17]]|0.436|
|[[:human genes:t:tbc1d3l|TBC1D3L]]|0.436|
|[[:human genes:t:tbc1d3e|TBC1D3E]]|0.436|
|[[:human genes:r:rps3a|RPS3A]]|0.436|
|[[:human genes:p:psmd3|PSMD3]]|0.435|
|[[:human genes:r:rnase3|RNASE3]]|0.434|
|[[:human genes:a:ankle2|ANKLE2]]|0.434|
|[[:human genes:r:rps12|RPS12]]|0.433|
|[[:human genes:i:ints6|INTS6]]|0.432|
|[[:human genes:t:tceb3cl|TCEB3CL]]|0.432|
|[[:human genes:v:vasn|VASN]]|0.431|
|[[:human genes:p:psmc1|PSMC1]]|0.431|
|[[:human genes:a:atp6v1c1|ATP6V1C1]]|0.43|
|[[:human genes:r:rrn3|RRN3]]|0.429|
|[[:human genes:c:ctage4|CTAGE4]]|0.428|
|[[:human genes:t:topbp1|TOPBP1]]|0.428|
|[[:human genes:r:ranbp2|RANBP2]]|0.427|
|[[:human genes:s:smg1|SMG1]]|0.427|
|[[:human genes:r:riok2|RIOK2]]|0.427|
|[[:human genes:p:psmb4|PSMB4]]|0.427|
|[[:human genes:m:myb|MYB]]|0.427|
|[[:human genes:n:nup107|NUP107]]|0.426|
|[[:human genes:p:psmc5|PSMC5]]|0.425|
|[[:human genes:t:tspy1|TSPY1]]|0.424|
|[[:human genes:r:rpl34|RPL34]]|0.423|
|[[:human genes:r:rpl35|RPL35]]|0.422|
|[[:human genes:a:atp6v0b|ATP6V0B]]|0.422|
|[[:human genes:r:rad21|RAD21]]|0.42|
|[[:human genes:e:elmod3|ELMOD3]]|0.42|
|[[:human genes:c:ctr9|CTR9]]|0.419|
|[[:human genes:b:bysl|BYSL]]|0.419|
|[[:human genes:p:psmc6|PSMC6]]|0.418|
|[[:human genes:r:rilpl2|RILPL2]]|0.417|
|[[:human genes:s:smg7|SMG7]]|0.416|
|[[:human genes:p:psmd6|PSMD6]]|0.416|
|[[:human genes:o:ogfr|OGFR]]|0.416|
|[[:human genes:s:scaf1|SCAF1]]|0.416|
|[[:human genes:w:wdr43|WDR43]]|0.413|
|[[:human genes:s:syt9|SYT9]]|0.413|
|[[:human genes:a:atp6ap2|ATP6AP2]]|0.412|
|[[:human genes:g:golga6l6|GOLGA6L6]]|0.412|
|[[:human genes:d:dtl|DTL]]|0.412|
|[[:human genes:c:cep192|CEP192]]|0.412|
|[[:human genes:c:ccdc116|CCDC116]]|0.41|
|[[:human genes:v:vps54|VPS54]]|0.41|
|[[:human genes:p:pwp2|PWP2]]|0.41|
|[[:human genes:o:or10g3|OR10G3]]|0.409|
|[[:human genes:n:nup205|NUP205]]|0.409|
|[[:human genes:s:slc4a1|SLC4A1]]|0.408|
|[[:human genes:g:golga8o|GOLGA8O]]|0.408|
|[[:human genes:r:rps2|RPS2]]|0.407|
|[[:human genes:d:ddx56|DDX56]]|0.406|
|[[:human genes:r:rnf121|RNF121]]|0.406|
|[[:human genes:s:shfm1|SHFM1]]|0.404|
|[[:human genes:t:top1mt|TOP1MT]]|0.404|
|[[:human genes:r:rad51|RAD51]]|0.403|
|[[:human genes:p:psmd14|PSMD14]]|0.403|
|[[:human genes:p:polr2j3|POLR2J3]]|0.403|
|[[:human genes:p:psmb1|PSMB1]]|0.402|
|[[:human genes:z:znf106|ZNF106]]|0.402|
|[[:human genes:s:sec13|SEC13]]|0.402|
|[[:human genes:d:dido1|DIDO1]]|0.401|
|[[:human genes:a:arcn1|ARCN1]]|0.401|
|[[:human genes:r:rnf113a|RNF113A]]|0.4|
|[[:human genes:d:dnm2|DNM2]]|0.4|
|[[:human genes:g:gprin2|GPRIN2]]|0.4|
|[[:human genes:h:hist2h2bf|HIST2H2BF]]|0.4|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 1/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|0/1|
|909776.0|0/1|
|bile duct|0/28|
|blood|0/28|
|bone|0/26|
|breast|1/33|
|central nervous system|0/56|
|cervix|0/4|
|colorectal|0/17|
|esophagus|0/13|
|fibroblast|0/1|
|gastric|0/16|
|kidney|0/21|
|liver|0/20|
|lung|0/75|
|lymphocyte|0/16|
|ovary|0/26|
|pancreas|0/24|
|peripheral nervous system|0/16|
|plasma cell|0/15|
|prostate|0/1|
|skin|0/24|
|soft tissue|0/9|
|thyroid|0/2|
|upper aerodigestive|0/22|
|urinary tract|0/29|
|uterus|0/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 2043
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 5.86 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='NBPF10 Expression in NALM6 Cells: 5.86'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>