======= NBPF16 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: NBPF15
  * **<color #00a2e8>Official Name</color>**: NBPF member 15
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=284565|284565]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q8N660|Q8N660]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=NBPF16&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20NBPF16|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: [[https://omim.org/entry/610414|Open OMIM]]

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='primary' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='default' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
|DUF1220|
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
No GO term information is available for this gene.
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp278|CVT-10216 0.1μM R06 exp278]]|1.88|
|[[:results:exp291|LLY-284 2.6μM R06 exp291]]|1.92|
|[[:results:exp29|Rapamycin 1μM R00 exp29]]|1.94|
|[[:results:exp229|Dimethyloxaloylglycine 100μM R05 exp229]]|1.96|
|[[:results:exp405|Tenofovir 10μM R07 exp405]]|2.18|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:s:ssh2|SSH2]]|0.505|
|[[:human genes:n:nupl1|NUPL1]]|0.481|
|[[:human genes:l:lad1|LAD1]]|0.468|
|[[:human genes:v:vasn|VASN]]|0.461|
|[[:human genes:c:cdca3|CDCA3]]|0.452|
|[[:human genes:d:ddtl|DDTL]]|0.451|
|[[:human genes:o:orc1|ORC1]]|0.449|
|[[:human genes:c:c1qtnf9b|C1QTNF9B]]|0.448|
|[[:human genes:p:psmb4|PSMB4]]|0.448|
|[[:human genes:s:stil|STIL]]|0.444|
|[[:human genes:z:zfand5|ZFAND5]]|0.443|
|[[:human genes:p:psmd11|PSMD11]]|0.441|
|[[:human genes:c:cdc45|CDC45]]|0.441|
|[[:human genes:p:psmd1|PSMD1]]|0.44|
|[[:human genes:n:nup107|NUP107]]|0.438|
|[[:human genes:h:hap1|HAP1]]|0.437|
|[[:human genes:p:psmc2|PSMC2]]|0.436|
|[[:human genes:c:copa|COPA]]|0.436|
|[[:human genes:p:psmd3|PSMD3]]|0.435|
|[[:human genes:p:psmc1|PSMC1]]|0.431|
|[[:human genes:t:tceb3cl2|TCEB3CL2]]|0.431|
|[[:human genes:p:psmc6|PSMC6]]|0.426|
|[[:human genes:i:iscu|ISCU]]|0.424|
|[[:human genes:r:rps28|RPS28]]|0.424|
|[[:human genes:c:cope|COPE]]|0.423|
|[[:human genes:g:golga6l3|GOLGA6L3]]|0.422|
|[[:human genes:a:akirin2|AKIRIN2]]|0.421|
|[[:human genes:r:rrp15|RRP15]]|0.42|
|[[:human genes:n:nhp2l1|NHP2L1]]|0.419|
|[[:human genes:p:psmb3|PSMB3]]|0.419|
|[[:human genes:s:smg1|SMG1]]|0.417|
|[[:human genes:r:rps2|RPS2]]|0.417|
|[[:human genes:g:gosr2|GOSR2]]|0.415|
|[[:human genes:c:cbwd5|CBWD5]]|0.415|
|[[:human genes:r:ranbp2|RANBP2]]|0.415|
|[[:human genes:z:znf106|ZNF106]]|0.414|
|[[:human genes:s:sart1|SART1]]|0.41|
|[[:human genes:c:cbwd3|CBWD3]]|0.408|
|[[:human genes:d:dtl|DTL]]|0.408|
|[[:human genes:r:rps12|RPS12]]|0.408|
|[[:human genes:o:orc6|ORC6]]|0.407|
|[[:human genes:c:chd4|CHD4]]|0.406|
|[[:human genes:r:rbbp5|RBBP5]]|0.406|
|[[:human genes:p:pde4dip|PDE4DIP]]|0.405|
|[[:human genes:c:csnk1a1|CSNK1A1]]|0.404|
|[[:human genes:n:nup205|NUP205]]|0.403|
|[[:human genes:c:c14orf93|C14orf93]]|0.403|
|[[:human genes:f:fam25b|FAM25B]]|0.403|
|[[:human genes:r:rps19bp1|RPS19BP1]]|0.403|
|[[:human genes:c:cbwd6|CBWD6]]|0.403|
|[[:human genes:p:psmd14|PSMD14]]|0.402|
|[[:human genes:s:syt9|SYT9]]|0.401|
|[[:human genes:g:golga6l4|GOLGA6L4]]|0.401|
|[[:human genes:r:rpl6|RPL6]]|0.4|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 2/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|0/1|
|909776.0|0/1|
|bile duct|1/28|
|blood|0/28|
|bone|0/26|
|breast|0/33|
|central nervous system|0/56|
|cervix|0/4|
|colorectal|0/17|
|esophagus|0/13|
|fibroblast|0/1|
|gastric|0/16|
|kidney|0/21|
|liver|0/20|
|lung|1/75|
|lymphocyte|0/16|
|ovary|0/26|
|pancreas|0/24|
|peripheral nervous system|0/16|
|plasma cell|0/15|
|prostate|0/1|
|skin|0/24|
|soft tissue|0/9|
|thyroid|0/2|
|upper aerodigestive|0/22|
|urinary tract|0/29|
|uterus|0/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 1860
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 5.27 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='NBPF16 Expression in NALM6 Cells: 5.27'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>