======= SPIN2A =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: SPIN2A
  * **<color #00a2e8>Official Name</color>**: spindlin family member 2A
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=54466|54466]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q99865|Q99865]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=SPIN2A&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20SPIN2A|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: [[https://omim.org/entry/300621|Open OMIM]]

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**:  This gene encodes one of three members of the DXF34 gene family, located in a 100-kb region of chromosome Xp11.21. [provided by RefSeq, Nov 2009]. 
  * **<color #00a2e8>UniProt Summary</color>**:  May be involved in the regulation of cell cycle progression (By similarity). Exhibits H3K4me3-binding activity (PubMed:29061846). {ECO:0000250|UniProtKB:Q9BPZ2, ECO:0000269|PubMed:29061846}.

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<modal id='GO_terms' size='lg' title='GO Terms'>
|methylated histone binding|
|gamete generation|
|multicellular organismal reproductive process|
|sexual reproduction|
|multicellular organism reproduction|
|multi-organism reproductive process|
|regulation of cell cycle|
|cell cycle|
|reproductive process|
|reproduction|
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 === CRISPR Data ===
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^Screen^Score^
|[[:results:exp85|UM0129480 7μM R02 exp85]]|1.74|
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No correlation found to any other genes in chemogenomics.
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Global Fraction of Cell Lines Where Essential: N/A
^Tissue^Fraction Of Cell Lines Where Essential^
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== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 15926
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 1.5 
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{{:chemogenomics:nalm6 dist.png?nolink |}}
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