======= SYBU =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: SYBU
  * **<color #00a2e8>Official Name</color>**: syntabulin
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=55638|55638]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q9NX95|Q9NX95]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=SYBU&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20SYBU|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: [[https://omim.org/entry/611568|Open OMIM]]

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='default' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
No Pfam Domain information is available for this gene.
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|regulation of synaptic activity|
|anterograde neuronal dense core vesicle transport|
|dense body|
|dense core granule localization|
|dense core granule transport|
|dense core granule cytoskeletal transport|
|secretory granule localization|
|axonal transport of mitochondrion|
|synapse maturation|
|mitochondrion transport along microtubule|
|establishment of mitochondrion localization, microtubule-mediated|
|establishment of mitochondrion localization|
|syntaxin-1 binding|
|positive regulation of insulin secretion involved in cellular response to glucose stimulus|
|kinesin binding|
|vesicle transport along microtubule|
|anterograde axonal transport|
|mitochondrion localization|
|vesicle cytoskeletal trafficking|
|axonal transport|
|regulation of insulin secretion involved in cellular response to glucose stimulus|
|axon cytoplasm|
|axo-dendritic transport|
|positive regulation of insulin secretion|
|organelle transport along microtubule|
|positive regulation of peptide hormone secretion|
|positive regulation of hormone secretion|
|vesicle|
|cytosolic transport|
|transport along microtubule|
|establishment of vesicle localization|
|cytoskeleton-dependent intracellular transport|
|regulation of insulin secretion|
|microtubule-based transport|
|vesicle localization|
|regulation of peptide hormone secretion|
|regulation of synapse structure or activity|
|microtubule binding|
|developmental maturation|
|cytoplasmic vesicle|
|regulation of hormone secretion|
|positive regulation of protein secretion|
|synapse organization|
|microtubule-based movement|
|positive regulation of peptide secretion|
|microtubule|
|establishment of organelle localization|
|positive regulation of secretion by cell|
|positive regulation of protein transport|
|positive regulation of secretion|
|modulation of chemical synaptic transmission|
|regulation of trans-synaptic signaling|
|positive regulation of establishment of protein localization|
|regulation of protein secretion|
|regulation of peptide secretion|
|regulation of hormone levels|
|organelle localization|
|Golgi membrane|
|microtubule-based process|
|intracellular membrane-bounded organelle|
|regulation of protein transport|
|regulation of peptide transport|
|regulation of establishment of protein localization|
|regulation of secretion by cell|
|regulation of secretion|
|regulation of cellular localization|
|positive regulation of transport|
|regulation of protein localization|
|intracellular transport|
|movement of cell or subcellular component|
|positive regulation of cell communication|
|positive regulation of signaling|
|establishment of localization in cell|
|regulation of transport|
</modal>
\\

 === CRISPR Data ===
<button type='default' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='default' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
No hits were found.
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
No correlation found to any other genes in chemogenomics.
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 0/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|0/1|
|909776.0|0/1|
|bile duct|0/28|
|blood|0/28|
|bone|0/26|
|breast|0/33|
|central nervous system|0/56|
|cervix|0/4|
|colorectal|0/17|
|esophagus|0/13|
|fibroblast|0/1|
|gastric|0/16|
|kidney|0/21|
|liver|0/20|
|lung|0/75|
|lymphocyte|0/16|
|ovary|0/26|
|pancreas|0/24|
|peripheral nervous system|0/16|
|plasma cell|0/15|
|prostate|0/1|
|skin|0/24|
|soft tissue|0/9|
|thyroid|0/2|
|upper aerodigestive|0/22|
|urinary tract|0/29|
|uterus|0/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 13331
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: -1.11 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='SYBU Expression in NALM6 Cells: -1.11'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>