======= TTC31 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: TTC31
  * **<color #00a2e8>Official Name</color>**: tetratricopeptide repeat domain 31
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=64427|64427]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q49AM3|Q49AM3]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=TTC31&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20TTC31|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**:  N/A

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='default' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='default' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
No Pfam Domain information is available for this gene.
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
No GO term information is available for this gene.
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp502|Milciclib 2μM R08 exp502]]|-1.75|
|[[:results:exp487|Hinokiflavone 12μM R08 exp487]]|-1.74|
|[[:results:exp177|Apcin 25μM plus proTAME 2μM R04 exp177]]|1.81|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:p:polr2j3|POLR2J3]]|0.606|
|[[:human genes:r:rpl30|RPL30]]|0.458|
|[[:human genes:h:hap1|HAP1]]|0.444|
|[[:human genes:t:tceb3c|TCEB3C]]|0.434|
|[[:human genes:p:psmb4|PSMB4]]|0.434|
|[[:human genes:a:aqr|AQR]]|0.434|
|[[:human genes:h:hist1h2be|HIST1H2BE]]|0.433|
|[[:human genes:s:supt6h|SUPT6H]]|0.429|
|[[:human genes:c:cdc45|CDC45]]|0.428|
|[[:human genes:p:psma6|PSMA6]]|0.426|
|[[:human genes:t:tceb3cl|TCEB3CL]]|0.419|
|[[:human genes:t:tbc1d3h|TBC1D3H]]|0.413|
|[[:human genes:r:rpl6|RPL6]]|0.412|
|[[:human genes:n:nup43|NUP43]]|0.411|
|[[:human genes:t:top1mt|TOP1MT]]|0.41|
|[[:human genes:t:tceb3cl2|TCEB3CL2]]|0.409|
|[[:human genes:t:tbc1d3f|TBC1D3F]]|0.405|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 0/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|0/1|
|909776.0|0/1|
|bile duct|0/28|
|blood|0/28|
|bone|0/26|
|breast|0/33|
|central nervous system|0/56|
|cervix|0/4|
|colorectal|0/17|
|esophagus|0/13|
|fibroblast|0/1|
|gastric|0/16|
|kidney|0/21|
|liver|0/20|
|lung|0/75|
|lymphocyte|0/16|
|ovary|0/26|
|pancreas|0/24|
|peripheral nervous system|0/16|
|plasma cell|0/15|
|prostate|0/1|
|skin|0/24|
|soft tissue|0/9|
|thyroid|0/2|
|upper aerodigestive|0/22|
|urinary tract|0/29|
|uterus|0/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 2295
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 5.54 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='TTC31 Expression in NALM6 Cells: 5.54'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>