======= UBAP2L =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: UBAP2L
  * **<color #00a2e8>Official Name</color>**: ubiquitin associated protein 2 like
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=9898|9898]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q14157|Q14157]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=UBAP2L&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20UBAP2L|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: [[https://omim.org/entry/616472|Open OMIM]]

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='primary' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
|DUF3697|
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|hematopoietic stem cell homeostasis|
|Ada2/Gcn5/Ada3 transcription activator complex|
|PcG protein complex|
|binding of sperm to zona pellucida|
|sperm-egg recognition|
|cell-cell recognition|
|single fertilization|
|fertilization|
|homeostasis of number of cells|
|cell recognition|
|sexual reproduction|
|multi-organism reproductive process|
|RNA binding|
|reproductive process|
|reproduction|
|homeostatic process|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp68|Clomiphene 4.4μM R02 exp68]]|-1.82|
|[[:results:exp500|LY2090314 0.003μM R08 exp500 no dilution day6]]|1.76|
|[[:results:exp46|HMS-I1 1μM R01 exp46]]|1.86|
|[[:results:exp65|Mubritinib 0.2μM R02 exp65]]|1.9|
|[[:results:exp80|RO-3307 4.7μM R02 exp80]]|1.91|
|[[:results:exp75|MK-1775 0.32μM R02 exp75]]|1.94|
|[[:results:exp264|Arsenate 40μM R06 exp264]]|2.04|
|[[:results:exp241|QNZ 0.01μM R05 exp241]]|2.26|
|[[:results:exp335|Aminopterin 0.005μM R07 exp335]]|2.37|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:p:prim1|PRIM1]]|0.494|
|[[:human genes:z:zfat|ZFAT]]|0.449|
|[[:human genes:p:pan2|PAN2]]|0.409|
|[[:human genes:y:ythdc1|YTHDC1]]|0.402|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 1/726
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|0/1|
|909776.0|0/1|
|bile duct|0/28|
|blood|0/28|
|bone|0/25|
|breast|0/33|
|central nervous system|0/56|
|cervix|0/4|
|colorectal|0/17|
|esophagus|0/13|
|fibroblast|0/1|
|gastric|0/15|
|kidney|0/21|
|liver|0/20|
|lung|0/75|
|lymphocyte|0/14|
|ovary|0/26|
|pancreas|0/24|
|peripheral nervous system|0/16|
|plasma cell|0/15|
|prostate|1/1|
|skin|0/24|
|soft tissue|0/7|
|thyroid|0/2|
|upper aerodigestive|0/22|
|urinary tract|0/29|
|uterus|0/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 1576
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 8.01 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='UBAP2L Expression in NALM6 Cells: 8.01'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>