======= USMG5 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: ATP5MD
  * **<color #00a2e8>Official Name</color>**: ATP synthase membrane subunit DAPIT
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=84833|84833]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q96IX5|Q96IX5]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=USMG5&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20USMG5|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**:  N/A

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**:  Plays a critical role in maintaining the ATP synthase population in mitochondria. {ECO:0000269|PubMed:21345788}.

<button type='default' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
No Pfam Domain information is available for this gene.
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|mitochondrial proton-transporting ATP synthase complex|
|mitochondrion|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='default' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp405|Tenofovir 10μM R07 exp405]]|-1.95|
|[[:results:exp416|Tubacin 1.6μM R07 exp416]]|-1.93|
|[[:results:exp336|Asunaprenir 3μM R07 exp336]]|-1.79|
|[[:results:exp465|Cannabidiol 13μM R08 exp465]]|-1.72|
|[[:results:exp184|Ixabepilone 0.004 to 0.005μM on day4 R04 exp184]]|1.7|
|[[:results:exp451|Atovaquone 15μM R08 exp451]]|1.72|
|[[:results:exp454|Bafilomycin-A1 0.009μM R08 exp454]]|1.75|
|[[:results:exp140|Nicotinate 1000μM R03 exp140]]|1.75|
|[[:results:exp460|BML-284 0.09μM R08 exp460]]|1.82|
|[[:results:exp32|Rifampicin 10μM R00 exp32]]|1.87|
|[[:results:exp487|Hinokiflavone 12μM R08 exp487]]|1.9|
|[[:results:exp84|UM0125461 0.74μM R02 exp84]]|2.26|
|[[:results:exp521|Salinomycin 3.5μM R08 exp521]]|2.37|
|[[:results:exp78|Pterostilbene 16μM R02 exp78]]|2.95|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
No correlation found to any other genes in chemogenomics.
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 0/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|0/1|
|909776.0|0/1|
|bile duct|0/28|
|blood|0/28|
|bone|0/26|
|breast|0/33|
|central nervous system|0/56|
|cervix|0/4|
|colorectal|0/17|
|esophagus|0/13|
|fibroblast|0/1|
|gastric|0/16|
|kidney|0/21|
|liver|0/20|
|lung|0/75|
|lymphocyte|0/16|
|ovary|0/26|
|pancreas|0/24|
|peripheral nervous system|0/16|
|plasma cell|0/15|
|prostate|0/1|
|skin|0/24|
|soft tissue|0/9|
|thyroid|0/2|
|upper aerodigestive|0/22|
|urinary tract|0/29|
|uterus|0/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 18575
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 5.46 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='USMG5 Expression in NALM6 Cells: 5.46'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>