======= WDR87 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: WDR87
  * **<color #00a2e8>Official Name</color>**: WD repeat domain 87
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=83889|83889]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q6ZQQ6|Q6ZQQ6]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=WDR87&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20WDR87|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: [[https://omim.org/entry/620274|Open OMIM]]

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='default' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='default' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
No Pfam Domain information is available for this gene.
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
No GO term information is available for this gene.
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp93|DABN racemic mixture R03 exp93]]|-1.8|
|[[:results:exp187|proTAME 5μM R04 exp187]]|1.7|
|[[:results:exp54|Taxol 0.002μM R01 exp54]]|1.87|
|[[:results:exp177|Apcin 25μM plus proTAME 2μM R04 exp177]]|1.88|
|[[:results:exp15|Cycloheximide 0.2μM R00 exp15]]|1.95|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:t:tceb3c|TCEB3C]]|0.544|
|[[:human genes:t:tceb3cl|TCEB3CL]]|0.541|
|[[:human genes:t:tceb3cl2|TCEB3CL2]]|0.537|
|[[:human genes:t:tbc1d3|TBC1D3]]|0.519|
|[[:human genes:d:dtl|DTL]]|0.516|
|[[:human genes:t:tbc1d3f|TBC1D3F]]|0.507|
|[[:human genes:c:c1qtnf9b|C1QTNF9B]]|0.507|
|[[:human genes:g:golga6l3|GOLGA6L3]]|0.504|
|[[:human genes:t:tbc1d3h|TBC1D3H]]|0.501|
|[[:human genes:c:c14orf93|C14orf93]]|0.498|
|[[:human genes:t:tfip11|TFIP11]]|0.497|
|[[:human genes:r:rps19bp1|RPS19BP1]]|0.492|
|[[:human genes:v:vasn|VASN]]|0.491|
|[[:human genes:t:tbc1d3e|TBC1D3E]]|0.49|
|[[:human genes:t:tbc1d3i|TBC1D3I]]|0.49|
|[[:human genes:c:ccdc64b|CCDC64B]]|0.49|
|[[:human genes:c:cbwd3|CBWD3]]|0.489|
|[[:human genes:t:tbc1d3l|TBC1D3L]]|0.489|
|[[:human genes:t:tbc1d3k|TBC1D3K]]|0.489|
|[[:human genes:p:psmd1|PSMD1]]|0.489|
|[[:human genes:g:golga6l4|GOLGA6L4]]|0.488|
|[[:human genes:c:cbwd5|CBWD5]]|0.487|
|[[:human genes:t:ticrr|TICRR]]|0.484|
|[[:human genes:r:rps2|RPS2]]|0.478|
|[[:human genes:c:crnkl1|CRNKL1]]|0.475|
|[[:human genes:n:nupl1|NUPL1]]|0.473|
|[[:human genes:r:rrn3|RRN3]]|0.472|
|[[:human genes:k:kctd17|KCTD17]]|0.47|
|[[:human genes:t:tbc1d3c|TBC1D3C]]|0.47|
|[[:human genes:t:tbc1d3g|TBC1D3G]]|0.468|
|[[:human genes:g:golga8o|GOLGA8O]]|0.467|
|[[:human genes:o:orc6|ORC6]]|0.462|
|[[:human genes:r:rps12|RPS12]]|0.462|
|[[:human genes:s:s1pr4|S1PR4]]|0.462|
|[[:human genes:r:rbbp5|RBBP5]]|0.46|
|[[:human genes:a:akirin2|AKIRIN2]]|0.46|
|[[:human genes:p:plk4|PLK4]]|0.459|
|[[:human genes:o:orc1|ORC1]]|0.458|
|[[:human genes:g:gon4l|GON4L]]|0.457|
|[[:human genes:s:ssh2|SSH2]]|0.456|
|[[:human genes:c:cdc73|CDC73]]|0.455|
|[[:human genes:p:psmc1|PSMC1]]|0.454|
|[[:human genes:d:ddtl|DDTL]]|0.452|
|[[:human genes:s:srgap2c|SRGAP2C]]|0.45|
|[[:human genes:n:nup43|NUP43]]|0.448|
|[[:human genes:p:psma6|PSMA6]]|0.447|
|[[:human genes:h:hivep3|HIVEP3]]|0.446|
|[[:human genes:a:add2|ADD2]]|0.444|
|[[:human genes:t:twistnb|TWISTNB]]|0.443|
|[[:human genes:n:nol12|NOL12]]|0.442|
|[[:human genes:s:snrpa1|SNRPA1]]|0.441|
|[[:human genes:m:mt1e|MT1E]]|0.439|
|[[:human genes:r:rpl6|RPL6]]|0.436|
|[[:human genes:s:sh3bp1|SH3BP1]]|0.435|
|[[:human genes:r:rpl34|RPL34]]|0.435|
|[[:human genes:a:akt1s1|AKT1S1]]|0.434|
|[[:human genes:c:cdca3|CDCA3]]|0.434|
|[[:human genes:c:ccdc94|CCDC94]]|0.434|
|[[:human genes:l:lrr1|LRR1]]|0.434|
|[[:human genes:p:psmb4|PSMB4]]|0.433|
|[[:human genes:z:znf106|ZNF106]]|0.433|
|[[:human genes:p:psmd3|PSMD3]]|0.433|
|[[:human genes:p:pigs|PIGS]]|0.432|
|[[:human genes:a:acsf2|ACSF2]]|0.429|
|[[:human genes:m:myo1h|MYO1H]]|0.428|
|[[:human genes:s:slc5a5|SLC5A5]]|0.427|
|[[:human genes:a:adra1d|ADRA1D]]|0.425|
|[[:human genes:c:cope|COPE]]|0.423|
|[[:human genes:a:abt1|ABT1]]|0.422|
|[[:human genes:s:sec13|SEC13]]|0.422|
|[[:human genes:r:rps14|RPS14]]|0.421|
|[[:human genes:c:chd4|CHD4]]|0.421|
|[[:human genes:d:ddt|DDT]]|0.419|
|[[:human genes:c:cbwd6|CBWD6]]|0.419|
|[[:human genes:c:cmya5|CMYA5]]|0.419|
|[[:human genes:m:myh2|MYH2]]|0.419|
|[[:human genes:c:cactin|CACTIN]]|0.418|
|[[:human genes:n:npipb5|NPIPB5]]|0.417|
|[[:human genes:c:copa|COPA]]|0.417|
|[[:human genes:c:cdc45|CDC45]]|0.417|
|[[:human genes:s:snrnp70|SNRNP70]]|0.417|
|[[:human genes:c:ccna2|CCNA2]]|0.416|
|[[:human genes:a:aqr|AQR]]|0.415|
|[[:human genes:m:mcoln1|MCOLN1]]|0.414|
|[[:human genes:k:krt78|KRT78]]|0.414|
|[[:human genes:a:ankle2|ANKLE2]]|0.414|
|[[:human genes:z:znf830|ZNF830]]|0.414|
|[[:human genes:a:ankle1|ANKLE1]]|0.414|
|[[:human genes:d:disp2|DISP2]]|0.413|
|[[:human genes:t:tp53tg3b|TP53TG3B]]|0.413|
|[[:human genes:z:znf219|ZNF219]]|0.413|
|[[:human genes:t:tspy1|TSPY1]]|0.413|
|[[:human genes:n:nol10|NOL10]]|0.413|
|[[:human genes:e:exd1|EXD1]]|0.412|
|[[:human genes:p:pan2|PAN2]]|0.412|
|[[:human genes:s:slc4a1|SLC4A1]]|0.412|
|[[:human genes:t:tp53tg3|TP53TG3]]|0.411|
|[[:human genes:t:tp53tg3c|TP53TG3C]]|0.411|
|[[:human genes:m:myt1l|MYT1L]]|0.41|
|[[:human genes:n:nup160|NUP160]]|0.41|
|[[:human genes:r:rffl|RFFL]]|0.41|
|[[:human genes:p:psmd11|PSMD11]]|0.409|
|[[:human genes:t:tra2b|TRA2B]]|0.409|
|[[:human genes:p:psmb2|PSMB2]]|0.408|
|[[:human genes:n:napa|NAPA]]|0.406|
|[[:human genes:c:clptm1|CLPTM1]]|0.406|
|[[:human genes:p:pwp2|PWP2]]|0.406|
|[[:human genes:s:stil|STIL]]|0.405|
|[[:human genes:g:golga6a|GOLGA6A]]|0.405|
|[[:human genes:h:hap1|HAP1]]|0.405|
|[[:human genes:c:col2a1|COL2A1]]|0.404|
|[[:human genes:p:psmb1|PSMB1]]|0.404|
|[[:human genes:e:esf1|ESF1]]|0.404|
|[[:human genes:t:top1mt|TOP1MT]]|0.404|
|[[:human genes:t:trim52|TRIM52]]|0.403|
|[[:human genes:h:hist2h3d|HIST2H3D]]|0.402|
|[[:human genes:r:rbm39|RBM39]]|0.402|
|[[:human genes:f:fam160a1|FAM160A1]]|0.402|
|[[:human genes:n:narfl|NARFL]]|0.402|
|[[:human genes:e:eif4a3|EIF4A3]]|0.402|
|[[:human genes:r:rnf113a|RNF113A]]|0.401|
|[[:human genes:c:cep55|CEP55]]|0.4|
|[[:human genes:p:ppm1d|PPM1D]]|0.4|
|[[:human genes:p:pla2g4f|PLA2G4F]]|0.4|
|[[:human genes:t:terf2|TERF2]]|0.4|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 0/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|0/1|
|909776.0|0/1|
|bile duct|0/28|
|blood|0/28|
|bone|0/26|
|breast|0/33|
|central nervous system|0/56|
|cervix|0/4|
|colorectal|0/17|
|esophagus|0/13|
|fibroblast|0/1|
|gastric|0/16|
|kidney|0/21|
|liver|0/20|
|lung|0/75|
|lymphocyte|0/16|
|ovary|0/26|
|pancreas|0/24|
|peripheral nervous system|0/16|
|plasma cell|0/15|
|prostate|0/1|
|skin|0/24|
|soft tissue|0/9|
|thyroid|0/2|
|upper aerodigestive|0/22|
|urinary tract|0/29|
|uterus|0/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 2486
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: -1.73 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='WDR87 Expression in NALM6 Cells: -1.73'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>