====== AICAR 240μM R03 exp116 ======
==== Mechanism of Action ====
Metabolic intermediate in purine biosynthesis, activates AMPK, has other putative targets
  * **<color #00a2e8>Class / Subclass 1:</color>** Metabolism / Metabolite
  * **<color #00a2e8>Class / Subclass 2:</color>** Signal Transduction / Kinase Activator



==== Technical Notes ====
<accordion collapsed='true'>
<panel title='Protein References' collapsed='true'>
    * **<color #00a2e8>PubChem Name:</color>** %%Acadesine%%
    * **<color #00a2e8>Synonyms:</color>** Acadesine; AICA Riboside
    * **<color #00a2e8>CAS #:</color>** 2627-69-2
    * **<color #00a2e8>PubChem CID:</color>** [[https://pubchem.ncbi.nlm.nih.gov/compound/17513|17513]]
    * **<color #00a2e8>IUPAC:</color>** %%5-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]imidazole-4-carboxamide%%
    * **<color #00a2e8>INCHI Name:</color>** InChI=1S/C9H14N4O5/c10-7-4(8(11)17)12-2-13(7)9-6(16)5(15)3(1-14)18-9/h2-3,5-6,9,14-16H,1,10H2,(H2,11,17)/t3-,5-,6-,9-/m1/s1
    * **<color #00a2e8>INCHI Key:</color>** RTRQQBHATOEIAF-UUOKFMHZSA-N
    * **<color #00a2e8>Molecular Weight:</color>** 258.23
    * **<color #00a2e8>Canonical SMILES:</color>** C1=NC(=C(N1C2C(C(C(O2)CO)O)O)N)C(=O)N
    * **<color #00a2e8>Isomeric SMILES:</color>** C1=NC(=C(N1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)N)C(=O)N
    * **<color #00a2e8>Molecular Formula:</color>** C9H14N4O5
{{:chemogenomics:structures:chem-0072.svg?nolink}}
</panel>


<panel title='Protein Supplier' collapsed='true'>
    * **<color #00a2e8>Supplier Name:</color>** AK scientific
    * **<color #00a2e8>Catalog #:</color>** AMTNS043
    * **<color #00a2e8>Lot #:</color>** DM-079-143-2
</panel>


<panel title='Protein Characterization' collapsed='true'>
    * **<color #00a2e8>LCMS:</color>** Tr 0.15 min, m/z 259+ [M+H]+, 257- [M-H]-
</panel>


<panel title='Dose Response Curve' collapsed='true'>
    * **<color #00a2e8>Platform ID:</color>** AICAR
    * **<color #00a2e8>Min:</color>** -11.2747; **<color #00a2e8>Max:</color>** 24.1473
{{:chemogenomics:dose_response:dr_68.png?nolink&500 |}}
\\ 
\\ 
\\ 
\\ 
|< 300px 100px 200px >|
^ IC   ^ Concentration (µM) ^
| IC10  |N/A    |
| IC20  |N/A    |
| IC30  |N/A    |
| IC40  |N/A    |
| IC50  |N/A    |
| IC60  |N/A    |
| IC70  |N/A    |
| IC80  |N/A    |
| IC90  |N/A    |
\\ 
</panel>
</accordion>
==== Screen Summary ====
    * **<color #00a2e8>Round</color>**: 03
    * **<color #00a2e8>Dose</color>**: 240µM
    * **<color #00a2e8>Days of incubation</color>**: 8
    * **<color #00a2e8>Doublings</color>**: 1.9
    * **<color #00a2e8>Numbers of reads</color>**: 10607864


==== Screen Results ====


^Sensitive/Resistant hits (FDR<0.05)^CRANKS^Score Plot^Top 30 Genes^Screen Similarity^Top 30 Sensitive GO terms^Top 30 Resistant GO terms^
|4/108|<color #e85500>[[https://files.tyerslab.com/files/public/chemogenomics/cranks/AICAR_240uM_Round-3_exp116.txt|Scores]]</color>|<button type="primary" size="sm" modal="ScorePlot">View</button>|<button type="primary" size="sm" modal="modal_hits">View</button>|<button type="primary" size="sm" modal="modal_screen_similarity">View</button>|<button type="default" size="sm" modal="modal_go_sensitive">View</button>|<button type="primary" size="sm" modal="modal_go_resistant">View</button>|
<modal id='ScorePlot' size='lg' title='AICAR 240μM R03 exp116'>
{{:chemogenomics:cranks_plots:exp116.png?nolink}}
</modal>


<modal id="modal_hits" size="sm" title="Top 30 S/R Genes">
^Gene^CRANKS Score^FDR^
|[[:human_genes:U:UCK2|UCK2]]|-4.05|<0.01|
|[[:human_genes:H:HCFC1|HCFC1]]|-3.67|0.17|
|[[:human_genes:N:NT5C2|NT5C2]]|-2.90|0.02|
|[[:human_genes:F:FAM122A|FAM122A]]|-2.68|0.04|
|[[:human_genes:N:NRAS|NRAS]]|-2.65|0.04|
|[[:human_genes:C:C7orf60|C7orf60]]|-2.55|0.11|
|[[:human_genes:C:CLK3|CLK3]]|-2.53|0.07|
|[[:human_genes:G:GNA13|GNA13]]|-2.48|0.07|
|[[:human_genes:T:TCF4|TCF4]]|-2.41|0.17|
|[[:human_genes:P:PROSER1|PROSER1]]|-2.39|0.16|
|[[:human_genes:A:ACIN1|ACIN1]]|-2.37|0.16|
|[[:human_genes:I:IRF4|IRF4]]|-2.35|0.16|
|[[:human_genes:N:NKAP|NKAP]]|-2.33|0.20|
|[[:human_genes:I:ING3|ING3]]|-2.32|0.14|
|[[:human_genes:M:MCM5|MCM5]]|-2.32|0.47|
|[[:human_genes:P:PLD2|PLD2]]|-2.32|0.17|
|[[:human_genes:K:KPNB1|KPNB1]]|-2.31|0.59|
|[[:human_genes:D:DRC1|DRC1]]|-2.30|0.14|
|[[:human_genes:C:CTC1|CTC1]]|-2.27|0.17|
|[[:human_genes:B:BTK|BTK]]|-2.26|0.16|
|[[:human_genes:T:TTC27|TTC27]]|-2.25|0.26|
|[[:human_genes:D:DCLRE1B|DCLRE1B]]|-2.21|0.16|
|[[:human_genes:S:SMG7|SMG7]]|-2.21|0.36|
|[[:human_genes:C:C9orf41|C9orf41]]|-2.20|0.27|
|[[:human_genes:I:IP6K1|IP6K1]]|-2.16|0.17|
|[[:human_genes:E:ERG|ERG]]|-2.14|0.23|
|[[:human_genes:A:ACSM1|ACSM1]]|-2.14|0.17|
|[[:human_genes:B:BICD1|BICD1]]|-2.12|0.17|
|[[:human_genes:B:BCL2|BCL2]]|-2.12|0.17|
|[[:human_genes:K:KEAP1|KEAP1]]|-2.09|0.18|
|[[:human_genes:G:GLRX5|GLRX5]]|3.65|<0.01|
|[[:human_genes:P:PIK3CD|PIK3CD]]|3.83|<0.01|
|[[:human_genes:S:SLC19A1|SLC19A1]]|3.85|<0.01|
|[[:human_genes:F:FAF2|FAF2]]|3.86|<0.01|
|[[:human_genes:T:TP53|TP53]]|3.96|<0.01|
|[[:human_genes:R:RICTOR|RICTOR]]|3.99|<0.01|
|[[:human_genes:C:CD19|CD19]]|4.04|<0.01|
|[[:human_genes:H:HEATR3|HEATR3]]|4.05|<0.01|
|[[:human_genes:B:BCL2L11|BCL2L11]]|4.13|<0.01|
|[[:human_genes:S:SLC25A51|SLC25A51]]|4.19|<0.01|
|[[:human_genes:N:NFU1|NFU1]]|4.23|<0.01|
|[[:human_genes:U:UBE2H|UBE2H]]|4.42|<0.01|
|[[:human_genes:M:MARCH5|MARCH5]]|4.71|<0.01|
|[[:human_genes:M:MTHFD1L|MTHFD1L]]|4.73|<0.01|
|[[:human_genes:M:MAPKAP1|MAPKAP1]]|4.89|<0.01|
|[[:human_genes:S:SHMT2|SHMT2]]|5.14|<0.01|
|[[:human_genes:S:SLC25A32|SLC25A32]]|5.30|<0.01|
|[[:human_genes:V:VDAC2|VDAC2]]|5.37|<0.01|
|[[:human_genes:M:MTHFD2|MTHFD2]]|5.41|<0.01|
|[[:human_genes:Y:YPEL5|YPEL5]]|5.57|<0.01|
|[[:human_genes:M:MTRR|MTRR]]|5.85|<0.01|
|[[:human_genes:I:IMPDH2|IMPDH2]]|5.89|<0.01|
|[[:human_genes:Y:YLPM1|YLPM1]]|6.11|<0.01|
|[[:human_genes:B:BAK1|BAK1]]|6.13|<0.01|
|[[:human_genes:M:MMACHC|MMACHC]]|6.57|<0.01|
|[[:human_genes:A:ADSS|ADSS]]|7.31|<0.01|
|[[:human_genes:M:MTR|MTR]]|7.47|<0.01|
|[[:human_genes:A:AK2|AK2]]|8.26|<0.01|
|[[:human_genes:N:NUDT2|NUDT2]]|8.48|<0.01|
|[[:human_genes:A:ADK|ADK]]|8.50|<0.01|
</modal>


<modal id="modal_screen_similarity" size="lg" title="Correlated Screens">
^Screen^Correlation^Plot^
|[[:results:exp211|AICAR 240μM R05 exp211]]|0.209|<button type="primary" size="small" modal="1">View</button>|
|[[:results:exp134|MS023 2μM R03 exp134]]|0.154|<button type="primary" size="small" modal="2">View</button>|
|[[:results:exp135|MS023 7μM R03 exp135]]|0.129|<button type="primary" size="small" modal="3">View</button>|
|[[:results:exp485|GSK626616 14μM R08 exp485]]|0.118|<button type="primary" size="small" modal="4">View</button>|
|[[:results:exp440|Aphidicolin 0.4μM R08 exp440]]|0.113|<button type="primary" size="small" modal="5">View</button>|
|[[:results:exp456|Benzoate 20000μM R08 exp456]]|0.104|<button type="primary" size="small" modal="6">View</button>|
|[[:results:exp488|Hippuristanol 0.12μM R08 exp488]]|0.102|<button type="primary" size="small" modal="7">View</button>|
|[[:results:exp535|Trimetrexate 0.03μM R08 exp535]]|0.099|<button type="primary" size="small" modal="8">View</button>|
|[[:results:exp234|Ethanol 0.01 R05 exp234]]|0.093|<button type="primary" size="small" modal="9">View</button>|
|[[:results:exp512|Olaparib 4μM R08 exp512]]|0.091|<button type="primary" size="small" modal="10">View</button>|
|[[:results:exp435|JQ1 0.8μM R08 exp435]]|0.09|<button type="primary" size="small" modal="11">View</button>|
|[[:results:exp3|Actinomycin-D 0.001μM R00 exp3]]|0.087|<button type="primary" size="small" modal="12">View</button>|
|[[:results:exp294|Nutlin-3A 1.6μM R06 exp294]]|0.084|<button type="primary" size="small" modal="13">View</button>|
|[[:results:exp489|Hippuristanol 0.12μM R08 exp489 no dilution day6]]|0.083|<button type="primary" size="small" modal="14">View</button>|
|[[:results:exp85|UM0129480 7μM R02 exp85]]|0.078|<button type="primary" size="small" modal="15">View</button>|
|[[:results:exp443|SNS-032 15μM R08 exp443]]|0.075|<button type="primary" size="small" modal="16">View</button>|
|[[:results:exp526|Sulforaphane 9μM R08 exp526 no dilution day6]]|0.074|<button type="primary" size="small" modal="17">View</button>|
|[[:results:exp450|Artemisinin 50μM R08 exp450]]|0.073|<button type="primary" size="small" modal="18">View</button>|
|[[:results:exp520|Rucaparib 6.5μM R08 exp520]]|0.073|<button type="primary" size="small" modal="19">View</button>|
|[[:results:exp80|RO-3307 4.7μM R02 exp80]]|0.072|<button type="primary" size="small" modal="20">View</button>|
|[[:results:exp492|iCRT14 30μM R08 exp492]]|0.069|<button type="primary" size="small" modal="21">View</button>|
|[[:results:exp503|Mitomycin-C 0.06μM R08 exp503]]|0.069|<button type="primary" size="small" modal="22">View</button>|
|[[:results:exp505|ML-792 0.2μM R08 exp505]]|0.068|<button type="primary" size="small" modal="23">View</button>|
|[[:results:exp525|Sulforaphane 9μM R08 exp525]]|0.068|<button type="primary" size="small" modal="24">View</button>|
|[[:results:exp472|CI-1040 9.5μM R08 exp472]]|0.068|<button type="primary" size="small" modal="25">View</button>|
|[[:results:exp274|Citral 50μM R06 exp274]]|0.065|<button type="primary" size="small" modal="26">View</button>|
|[[:results:exp474|CR131-b 0.005μM R08 exp474]]|0.063|<button type="primary" size="small" modal="27">View</button>|
|[[:results:exp355|Dinaciclib 0.007μM R07 exp355]]|0.061|<button type="primary" size="small" modal="28">View</button>|
|[[:results:exp199|Etoposide 0.3μM R05 exp199]]|0.061|<button type="primary" size="small" modal="29">View</button>|
|[[:results:exp451|Atovaquone 15μM R08 exp451]]|0.06|<button type="primary" size="small" modal="30">View</button>|
|[[:results:exp441|GSK-J4 1.5μM R08 exp441]]|0.059|<button type="primary" size="small" modal="31">View</button>|
|[[:results:exp357|Dorsomorphin 5μM R07 exp357]]|0.059|<button type="primary" size="small" modal="32">View</button>|
|[[:results:exp459|Bleomycin 5μM R08 exp459]]|0.055|<button type="primary" size="small" modal="33">View</button>|
|[[:results:exp498|Lead acetate 2000μM R08 exp498 no dilution day6]]|0.054|<button type="primary" size="small" modal="34">View</button>|
|[[:results:exp517|Quercetin 20μM R08 exp517]]|0.054|<button type="primary" size="small" modal="35">View</button>|
|[[:results:exp363|GSK-J4 1-1.25μM to day4 R07 exp363]]|0.054|<button type="primary" size="small" modal="36">View</button>|
|[[:results:exp21|MLN-4924 0.2μM R00 exp21]]|0.054|<button type="primary" size="small" modal="37">View</button>|
|[[:results:exp478|Doxorubicin 0.02μM R08 exp478]]|0.054|<button type="primary" size="small" modal="38">View</button>|
|[[:results:exp264|Arsenate 40μM R06 exp264]]|0.053|<button type="primary" size="small" modal="39">View</button>|
|[[:results:exp354|Diepoxybutane 3μM R07 exp354]]|0.053|<button type="primary" size="small" modal="40">View</button>|
|[[:results:exp374|Latrunculin-B 10μM R07 exp374]]|0.053|<button type="primary" size="small" modal="41">View</button>|
|[[:results:exp439|QNZ 0.01μM R08 exp439]]|0.052|<button type="primary" size="small" modal="42">View</button>|
|[[:results:exp529|Thimerosal 0.85μM R08 exp529]]|0.052|<button type="primary" size="small" modal="43">View</button>|
|[[:results:exp524|Staurosporine 0.02μM R08 exp524]]|0.051|<button type="primary" size="small" modal="44">View</button>|
|[[:results:exp2|5-Fluorouracil 20μM R00 exp2]]|0.072|<button type="primary" size="small" modal="45">View</button>|
|[[:results:exp259|6-Thio-2-deoxyguanosine 2μM R06 exp259]]|0.063|<button type="primary" size="small" modal="46">View</button>|
</modal>


<modal id="1" size="lg" title="AICAR 240μM R03 exp116  vs  AICAR 240μM R05 exp211">
{{:chemogenomics:comparison_plots:exp116_vs_exp211.png?nolink |}}
</modal>

<modal id="2" size="lg" title="AICAR 240μM R03 exp116  vs  MS023 2μM R03 exp134">
{{:chemogenomics:comparison_plots:exp116_vs_exp134.png?nolink |}}
</modal>

<modal id="3" size="lg" title="AICAR 240μM R03 exp116  vs  MS023 7μM R03 exp135">
{{:chemogenomics:comparison_plots:exp116_vs_exp135.png?nolink |}}
</modal>

<modal id="4" size="lg" title="AICAR 240μM R03 exp116  vs  GSK626616 14μM R08 exp485">
{{:chemogenomics:comparison_plots:exp116_vs_exp485.png?nolink |}}
</modal>

<modal id="5" size="lg" title="AICAR 240μM R03 exp116  vs  Aphidicolin 0.4μM R08 exp440">
{{:chemogenomics:comparison_plots:exp116_vs_exp440.png?nolink |}}
</modal>

<modal id="6" size="lg" title="AICAR 240μM R03 exp116  vs  Benzoate 20000μM R08 exp456">
{{:chemogenomics:comparison_plots:exp116_vs_exp456.png?nolink |}}
</modal>

<modal id="7" size="lg" title="AICAR 240μM R03 exp116  vs  Hippuristanol 0.12μM R08 exp488">
{{:chemogenomics:comparison_plots:exp116_vs_exp488.png?nolink |}}
</modal>

<modal id="8" size="lg" title="AICAR 240μM R03 exp116  vs  Trimetrexate 0.03μM R08 exp535">
{{:chemogenomics:comparison_plots:exp116_vs_exp535.png?nolink |}}
</modal>

<modal id="9" size="lg" title="AICAR 240μM R03 exp116  vs  Ethanol 0.01 R05 exp234">
{{:chemogenomics:comparison_plots:exp116_vs_exp234.png?nolink |}}
</modal>

<modal id="10" size="lg" title="AICAR 240μM R03 exp116  vs  Olaparib 4μM R08 exp512">
{{:chemogenomics:comparison_plots:exp116_vs_exp512.png?nolink |}}
</modal>

<modal id="11" size="lg" title="AICAR 240μM R03 exp116  vs  JQ1 0.8μM R08 exp435">
{{:chemogenomics:comparison_plots:exp116_vs_exp435.png?nolink |}}
</modal>

<modal id="12" size="lg" title="AICAR 240μM R03 exp116  vs  Actinomycin-D 0.001μM R00 exp3">
{{:chemogenomics:comparison_plots:exp116_vs_exp3.png?nolink |}}
</modal>

<modal id="13" size="lg" title="AICAR 240μM R03 exp116  vs  Nutlin-3A 1.6μM R06 exp294">
{{:chemogenomics:comparison_plots:exp116_vs_exp294.png?nolink |}}
</modal>

<modal id="14" size="lg" title="AICAR 240μM R03 exp116  vs  Hippuristanol 0.12μM R08 exp489 no dilution day6">
{{:chemogenomics:comparison_plots:exp116_vs_exp489.png?nolink |}}
</modal>

<modal id="15" size="lg" title="AICAR 240μM R03 exp116  vs  UM0129480 7μM R02 exp85">
{{:chemogenomics:comparison_plots:exp116_vs_exp85.png?nolink |}}
</modal>

<modal id="16" size="lg" title="AICAR 240μM R03 exp116  vs  SNS-032 15μM R08 exp443">
{{:chemogenomics:comparison_plots:exp116_vs_exp443.png?nolink |}}
</modal>

<modal id="17" size="lg" title="AICAR 240μM R03 exp116  vs  Sulforaphane 9μM R08 exp526 no dilution day6">
{{:chemogenomics:comparison_plots:exp116_vs_exp526.png?nolink |}}
</modal>

<modal id="18" size="lg" title="AICAR 240μM R03 exp116  vs  Artemisinin 50μM R08 exp450">
{{:chemogenomics:comparison_plots:exp116_vs_exp450.png?nolink |}}
</modal>

<modal id="19" size="lg" title="AICAR 240μM R03 exp116  vs  Rucaparib 6.5μM R08 exp520">
{{:chemogenomics:comparison_plots:exp116_vs_exp520.png?nolink |}}
</modal>

<modal id="20" size="lg" title="AICAR 240μM R03 exp116  vs  RO-3307 4.7μM R02 exp80">
{{:chemogenomics:comparison_plots:exp116_vs_exp80.png?nolink |}}
</modal>

<modal id="21" size="lg" title="AICAR 240μM R03 exp116  vs  iCRT14 30μM R08 exp492">
{{:chemogenomics:comparison_plots:exp116_vs_exp492.png?nolink |}}
</modal>

<modal id="22" size="lg" title="AICAR 240μM R03 exp116  vs  Mitomycin-C 0.06μM R08 exp503">
{{:chemogenomics:comparison_plots:exp116_vs_exp503.png?nolink |}}
</modal>

<modal id="23" size="lg" title="AICAR 240μM R03 exp116  vs  ML-792 0.2μM R08 exp505">
{{:chemogenomics:comparison_plots:exp116_vs_exp505.png?nolink |}}
</modal>

<modal id="24" size="lg" title="AICAR 240μM R03 exp116  vs  Sulforaphane 9μM R08 exp525">
{{:chemogenomics:comparison_plots:exp116_vs_exp525.png?nolink |}}
</modal>

<modal id="25" size="lg" title="AICAR 240μM R03 exp116  vs  CI-1040 9.5μM R08 exp472">
{{:chemogenomics:comparison_plots:exp116_vs_exp472.png?nolink |}}
</modal>

<modal id="26" size="lg" title="AICAR 240μM R03 exp116  vs  Citral 50μM R06 exp274">
{{:chemogenomics:comparison_plots:exp116_vs_exp274.png?nolink |}}
</modal>

<modal id="27" size="lg" title="AICAR 240μM R03 exp116  vs  CR131-b 0.005μM R08 exp474">
{{:chemogenomics:comparison_plots:exp116_vs_exp474.png?nolink |}}
</modal>

<modal id="28" size="lg" title="AICAR 240μM R03 exp116  vs  Dinaciclib 0.007μM R07 exp355">
{{:chemogenomics:comparison_plots:exp116_vs_exp355.png?nolink |}}
</modal>

<modal id="29" size="lg" title="AICAR 240μM R03 exp116  vs  Etoposide 0.3μM R05 exp199">
{{:chemogenomics:comparison_plots:exp116_vs_exp199.png?nolink |}}
</modal>

<modal id="30" size="lg" title="AICAR 240μM R03 exp116  vs  Atovaquone 15μM R08 exp451">
{{:chemogenomics:comparison_plots:exp116_vs_exp451.png?nolink |}}
</modal>

<modal id="31" size="lg" title="AICAR 240μM R03 exp116  vs  GSK-J4 1.5μM R08 exp441">
{{:chemogenomics:comparison_plots:exp116_vs_exp441.png?nolink |}}
</modal>

<modal id="32" size="lg" title="AICAR 240μM R03 exp116  vs  Dorsomorphin 5μM R07 exp357">
{{:chemogenomics:comparison_plots:exp116_vs_exp357.png?nolink |}}
</modal>

<modal id="33" size="lg" title="AICAR 240μM R03 exp116  vs  Bleomycin 5μM R08 exp459">
{{:chemogenomics:comparison_plots:exp116_vs_exp459.png?nolink |}}
</modal>

<modal id="34" size="lg" title="AICAR 240μM R03 exp116  vs  Lead acetate 2000μM R08 exp498 no dilution day6">
{{:chemogenomics:comparison_plots:exp116_vs_exp498.png?nolink |}}
</modal>

<modal id="35" size="lg" title="AICAR 240μM R03 exp116  vs  Quercetin 20μM R08 exp517">
{{:chemogenomics:comparison_plots:exp116_vs_exp517.png?nolink |}}
</modal>

<modal id="36" size="lg" title="AICAR 240μM R03 exp116  vs  GSK-J4 1-1.25μM to day4 R07 exp363">
{{:chemogenomics:comparison_plots:exp116_vs_exp363.png?nolink |}}
</modal>

<modal id="37" size="lg" title="AICAR 240μM R03 exp116  vs  MLN-4924 0.2μM R00 exp21">
{{:chemogenomics:comparison_plots:exp116_vs_exp21.png?nolink |}}
</modal>

<modal id="38" size="lg" title="AICAR 240μM R03 exp116  vs  Doxorubicin 0.02μM R08 exp478">
{{:chemogenomics:comparison_plots:exp116_vs_exp478.png?nolink |}}
</modal>

<modal id="39" size="lg" title="AICAR 240μM R03 exp116  vs  Arsenate 40μM R06 exp264">
{{:chemogenomics:comparison_plots:exp116_vs_exp264.png?nolink |}}
</modal>

<modal id="40" size="lg" title="AICAR 240μM R03 exp116  vs  Diepoxybutane 3μM R07 exp354">
{{:chemogenomics:comparison_plots:exp116_vs_exp354.png?nolink |}}
</modal>

<modal id="41" size="lg" title="AICAR 240μM R03 exp116  vs  Latrunculin-B 10μM R07 exp374">
{{:chemogenomics:comparison_plots:exp116_vs_exp374.png?nolink |}}
</modal>

<modal id="42" size="lg" title="AICAR 240μM R03 exp116  vs  QNZ 0.01μM R08 exp439">
{{:chemogenomics:comparison_plots:exp116_vs_exp439.png?nolink |}}
</modal>

<modal id="43" size="lg" title="AICAR 240μM R03 exp116  vs  Thimerosal 0.85μM R08 exp529">
{{:chemogenomics:comparison_plots:exp116_vs_exp529.png?nolink |}}
</modal>

<modal id="44" size="lg" title="AICAR 240μM R03 exp116  vs  Staurosporine 0.02μM R08 exp524">
{{:chemogenomics:comparison_plots:exp116_vs_exp524.png?nolink |}}
</modal>

<modal id="45" size="lg" title="5-Fluorouracil 20μM R00 exp2  vs  AICAR 240μM R03 exp116">
{{:chemogenomics:comparison_plots:exp116_vs_exp2.png?nolink |}}
</modal>

<modal id="46" size="lg" title="6-Thio-2-deoxyguanosine 2μM R06 exp259  vs  AICAR 240μM R03 exp116">
{{:chemogenomics:comparison_plots:exp116_vs_exp259.png?nolink |}}
</modal>



<modal id="modal_go_sensitive" size="lg" title="Top 30 sensitive GO terms">No GO term hits below threshold. (FDR <0.05)</modal>
<modal id="modal_go_resistant" size="lg" title="Top 30 resistant GO terms">
^GO Term^Fold Change^Genes^
|tetrahydrofolate interconversion|207.24|MTHFD2,SHMT2,MTHFD1L|
|tetrahydrofolate metabolic process|157.90|MTR,MTHFD2,SHMT2,MTHFD1L|
|folic acid metabolic process|157.90|MTHFD2,SLC25A32,SHMT2,SLC19A1|
|folic acid-containing compound metabolic process|132.63|MTR,MTRR,MTHFD2,SHMT2,MTHFD1L,SLC19A1|
|pteridine-containing compound metabolic process|124.79|MTR,MTRR,MTHFD2,SLC25A32,SHMT2,MTHFD1L,SLC19A1|
|purine ribonucleoside monophosphate biosynthetic process|122.81|ADK,NUDT2,ADSS2,IMPDH2|
|purine nucleoside monophosphate biosynthetic process|110.53|ADK,NUDT2,ADSS2,IMPDH2|
|AMP metabolic process|100.48|ADK,NUDT2,AK2,ADSS2|
|positive regulation of mitochondrial membrane permeability|78.95|BAK1,VDAC2,BCL2L11,TP53|
|positive regulation of membrane permeability|71.31|BAK1,VDAC2,BCL2L11,TP53|
|purine ribonucleoside monophosphate metabolic process|69.08|ADK,NUDT2,AK2,ADSS2,IMPDH2|
|water-soluble vitamin metabolic process|66.70|MTR,MMACHC,MTRR,MTHFD2,SLC25A32,SHMT2,SLC19A1|
|purine nucleoside monophosphate metabolic process|65.79|ADK,NUDT2,AK2,ADSS2,IMPDH2|
|ribonucleoside monophosphate biosynthetic process|65.02|ADK,NUDT2,ADSS2,IMPDH2|
|ribonucleoside monophosphate metabolic process|46.83|ADK,NUDT2,AK2,ADSS2,IMPDH2|
|dicarboxylic acid metabolic process|43.96|ADSS2,MTRR,MTHFD2,SLC25A32,SHMT2,MTHFD1L,SLC19A1|
|vitamin metabolic process|39.88|MTR,MMACHC,MTRR,MTHFD2,SLC25A32,SHMT2,SLC19A1|
|nucleoside monophosphate metabolic process|36.36|ADK,NUDT2,AK2,ADSS2,IMPDH2|
|cellular modified amino acid metabolic process|33.93|MTR,MTRR,MTHFD2,SLC25A32,SHMT2,MTHFD1L,SLC19A1|
</modal>