UniProt Summary: Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids (By similarity). {ECO:0000250}.
Pfam DomainsGO Terms
Pfam Domains
AstE AspA
GO Terms
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
aminoacylase activity
hydrolase activity, acting on ester bonds
xenobiotic metabolic process
cellular response to xenobiotic stimulus
response to xenobiotic stimulus
apical plasma membrane
viral process
molecular function
symbiotic process
interspecies interaction between organisms
identical protein binding
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739