AMELY

• Official Symbol: AMELY
• Official Name: amelogenin Y-linked
• Aliases and Previous Symbols: N/A
• Entrez ID: 266
• UniProt: Q99218
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: Open OMIM

• Entrez Summary: This gene encodes a member of the amelogenin family of extracellular matrix proteins. Amelogenins are involved in biomineralization during tooth enamel development. Mutations in a related gene on chromosome X cause X-linked amelogenesis imperfecta. [provided by RefSeq, Jul 2008].
• UniProt Summary: Plays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 17399
• Expression level (log2 read counts): -7.68

Expression Distribution

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AMELY Expression in NALM6 Cells: -7.68