Pfam Domains GO Terms
| Ceramidase alk |
| N-acylsphingosine amidohydrolase activity |
| sphingosine biosynthetic process |
| sphingoid biosynthetic process |
| sphingosine metabolic process |
| sphingoid metabolic process |
| diol biosynthetic process |
| ceramide catabolic process |
| diol metabolic process |
| long-chain fatty acid biosynthetic process |
| sphingolipid catabolic process |
| membrane lipid catabolic process |
| polyol biosynthetic process |
| ceramide metabolic process |
| sphingolipid biosynthetic process |
| polyol metabolic process |
| alcohol biosynthetic process |
| long-chain fatty acid metabolic process |
| fatty acid biosynthetic process |
| membrane lipid biosynthetic process |
| sphingolipid metabolic process |
| monocarboxylic acid biosynthetic process |
| organic hydroxy compound biosynthetic process |
| ammonium ion metabolic process |
| cellular lipid catabolic process |
| membrane lipid metabolic process |
| lipid catabolic process |
| carboxylic acid biosynthetic process |
| organic acid biosynthetic process |
| alcohol metabolic process |
| fatty acid metabolic process |
| organic hydroxy compound metabolic process |
| monocarboxylic acid metabolic process |
| lipid biosynthetic process |
| small molecule biosynthetic process |
| cellular amide metabolic process |
| carboxylic acid metabolic process |
| cellular lipid metabolic process |
| oxoacid metabolic process |
| organic acid metabolic process |
| organonitrogen compound catabolic process |
| lipid metabolic process |
| organonitrogen compound biosynthetic process |
| cellular nitrogen compound biosynthetic process |
| small molecule metabolic process |
| organic substance catabolic process |
| cellular catabolic process |
| extracellular region |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Screen | Score |
|---|---|
| Ibrutinib 10μM R08 exp442 | -1.74 |
| FBS-Wisent 0.1 R07 exp426 | 1.97 |
| Gene | Correlation |
|---|---|
| HGC6.3 | 0.448 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution