ATP6V0E2
Gene Information
- Official Symbol: ATP6V0E2
- Official Name: ATPase H+ transporting V0 subunit e2
- Aliases and Previous Symbols: N/A
- Entrez ID: 155066
- UniProt: Q8NHE4
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| ATP synt H |
GO Terms
| ATPase-coupled ion transmembrane transporter activity |
| proton-transporting V-type ATPase, V0 domain |
| vacuolar acidification |
| proton-transporting ATPase activity, rotational mechanism |
| phagosome acidification |
| transferrin transport |
| phagosome maturation |
| intracellular pH reduction |
| pH reduction |
| iron ion transport |
| phagocytic vesicle membrane |
| hydrolase activity |
| regulation of intracellular pH |
| insulin receptor signaling pathway |
| regulation of cellular pH |
| regulation of pH |
| cellular monovalent inorganic cation homeostasis |
| transition metal ion transport |
| monovalent inorganic cation homeostasis |
| proton transmembrane transport |
| cellular response to insulin stimulus |
| regulation of macroautophagy |
| endosome membrane |
| response to insulin |
| cellular response to peptide hormone stimulus |
| cellular response to peptide |
| regulation of autophagy |
| response to peptide hormone |
| monovalent inorganic cation transport |
| response to peptide |
| transmembrane receptor protein tyrosine kinase signaling pathway |
| inorganic cation transmembrane transport |
| cellular response to organonitrogen compound |
| cellular response to hormone stimulus |
| cation transmembrane transport |
| cellular cation homeostasis |
| metal ion transport |
| cellular ion homeostasis |
| inorganic ion transmembrane transport |
| cellular response to nitrogen compound |
| cation homeostasis |
| enzyme linked receptor protein signaling pathway |
| inorganic ion homeostasis |
| cellular chemical homeostasis |
| ion homeostasis |
| cation transport |
| regulation of cellular catabolic process |
| cellular homeostasis |
| response to hormone |
| ion transmembrane transport |
| regulation of catabolic process |
| response to organonitrogen compound |
| cellular response to oxygen-containing compound |
| response to nitrogen compound |
| chemical homeostasis |
| cellular response to endogenous stimulus |
| transmembrane transport |
| ion transport |
| response to endogenous stimulus |
| protein transport |
| peptide transport |
| response to oxygen-containing compound |
| amide transport |
| establishment of protein localization |
| homeostatic process |
| nitrogen compound transport |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
| Screen | Score |
|---|---|
| Calcipotriol 5μM R08 exp464 | 1.83 |
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 9379
- Expression level (log2 read counts): 3.49
Expression Distribution
ATP6V0E2 Expression in NALM6 Cells: 3.49
