UniProt Summary: May regulate cell proliferation and coordinate apoptosis and cell cycle progression via a novel mechanism independent of both p53/TP53 and NF-kappa-B. {ECO:0000269|PubMed:17031575}.
Pfam DomainsGO Terms
Pfam Domains
BC10
GO Terms
apoptotic nuclear changes
cellular component disassembly involved in execution phase of apoptosis
execution phase of apoptosis
cellular component disassembly
apoptotic process
programmed cell death
cell death
cell cycle
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)