UniProt Summary: Binds sperm in vitro and promotes sperm capacitation. Specifically promotes capacitation induced by high density lipoproteins (HDLs). Also binds heparin, phospholipid liposomes, and weakly to gelatin. Does not bind chondroitin sulfate B. {ECO:0000250|UniProtKB:Q3UW26}.
Pfam DomainsGO Terms
Pfam Domains
fn2
GO Terms
sperm capacitation
single fertilization
spermatid development
spermatid differentiation
cell maturation
fertilization
heparin binding
developmental maturation
germ cell development
cellular process involved in reproduction in multicellular organism
spermatogenesis
male gamete generation
cell surface
developmental process involved in reproduction
gamete generation
multicellular organismal reproductive process
sexual reproduction
multicellular organism reproduction
multi-organism reproductive process
reproductive process
reproduction
cell development
extracellular region
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)