BZRAP1
Gene Information
- Official Symbol: TSPOAP1
- Official Name: TSPO associated protein 1
- Aliases and Previous Symbols: N/A
- Entrez ID: 9256
- UniProt: O95153
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| SH3 2 |
GO Terms
| voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels |
| benzodiazepine receptor binding |
| C21-steroid hormone biosynthetic process |
| regulation of presynaptic cytosolic calcium ion concentration |
| calyx of Held |
| C21-steroid hormone metabolic process |
| glutamate secretion |
| neuromuscular synaptic transmission |
| neuron cellular homeostasis |
| steroid hormone biosynthetic process |
| acidic amino acid transport |
| hormone biosynthetic process |
| dicarboxylic acid transport |
| acid secretion |
| neurotransmitter secretion |
| signal release from synapse |
| amino acid transport |
| cellular hormone metabolic process |
| steroid biosynthetic process |
| signal release |
| neurotransmitter transport |
| hormone metabolic process |
| steroid metabolic process |
| organic acid transport |
| carboxylic acid transport |
| regulation of cytosolic calcium ion concentration |
| anatomical structure homeostasis |
| glutamatergic synapse |
| regulation of neurotransmitter levels |
| chemical synaptic transmission |
| anterograde trans-synaptic signaling |
| cellular calcium ion homeostasis |
| trans-synaptic signaling |
| calcium ion homeostasis |
| organic anion transport |
| synaptic signaling |
| cellular divalent inorganic cation homeostasis |
| divalent inorganic cation homeostasis |
| regulation of hormone levels |
| cellular metal ion homeostasis |
| lipid biosynthetic process |
| anion transport |
| metal ion homeostasis |
| cellular cation homeostasis |
| cellular ion homeostasis |
| cation homeostasis |
| inorganic ion homeostasis |
| cellular chemical homeostasis |
| ion homeostasis |
| cellular homeostasis |
| secretion by cell |
| export from cell |
| chemical homeostasis |
| cell-cell signaling |
| secretion |
| lipid metabolic process |
| mitochondrion |
| organic cyclic compound biosynthetic process |
| ion transport |
| homeostatic process |
| establishment of localization in cell |
| nitrogen compound transport |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 4476
- Expression level (log2 read counts): 5.58
Expression Distribution
BZRAP1 Expression in NALM6 Cells: 5.58
