C15orf62
Gene Information
- Official Symbol: C15orf62
- Official Name: chromosome 15 open reading frame 62
- Aliases and Previous Symbols: N/A
- Entrez ID: 643338
- UniProt: A8K5M9
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: N/A
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
No Pfam Domain information is available for this gene.
GO Terms
| positive regulation of pseudopodium assembly |
| regulation of pseudopodium assembly |
| GTP-Rho binding |
| Rho protein signal transduction |
| positive regulation of actin filament polymerization |
| positive regulation of plasma membrane bounded cell projection assembly |
| positive regulation of protein polymerization |
| regulation of cell shape |
| regulation of actin filament polymerization |
| regulation of actin polymerization or depolymerization |
| regulation of actin filament length |
| positive regulation of supramolecular fiber organization |
| regulation of plasma membrane bounded cell projection assembly |
| regulation of cell projection assembly |
| positive regulation of cytoskeleton organization |
| regulation of protein polymerization |
| Ras protein signal transduction |
| positive regulation of protein complex assembly |
| regulation of actin filament organization |
| small GTPase mediated signal transduction |
| regulation of actin cytoskeleton organization |
| regulation of supramolecular fiber organization |
| regulation of cellular component size |
| positive regulation of cell projection organization |
| regulation of actin filament-based process |
| regulation of protein complex assembly |
| regulation of cell morphogenesis |
| regulation of anatomical structure size |
| positive regulation of cellular component biogenesis |
| regulation of cytoskeleton organization |
| positive regulation of organelle organization |
| regulation of plasma membrane bounded cell projection organization |
| regulation of cell projection organization |
| regulation of cellular component biogenesis |
| regulation of anatomical structure morphogenesis |
| positive regulation of cellular component organization |
| mitochondrion |
| regulation of organelle organization |
| intracellular signal transduction |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
| Screen | Score |
|---|---|
| HMS-I2 10μM R06 exp288 | -2.08 |
| SB743921 0.001μM R05 exp244 | -2 |
| UM131593 0.1μM R01 exp58 | -1.81 |
| CI-1040 9.5μM R08 exp472 | -1.75 |
| Etoposide 0.3μM R05 exp199 | 1.87 |
Most Correlated Genes in Chemogenomics
| Gene | Correlation |
|---|---|
| HGC6.3 | 0.451 |
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 4145
- Expression level (log2 read counts): 1.41
Expression Distribution
C15orf62 Expression in NALM6 Cells: 6.23
