CD22
Gene Information
- Official Symbol: CD22
- Official Name: CD22 molecule
- Aliases and Previous Symbols: N/A
- Entrez ID: 933
- UniProt: P20273
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| C2-set 2 |
| I-set |
| ig |
GO Terms
| IgM binding |
| negative regulation of immunoglobulin secretion |
| negative regulation of B cell receptor signaling pathway |
| CD4 receptor binding |
| negative regulation of immunoglobulin production |
| sialic acid binding |
| regulation of immunoglobulin secretion |
| regulation of B cell receptor signaling pathway |
| negative regulation of antigen receptor-mediated signaling pathway |
| neuronal cell body membrane |
| negative regulation of calcium-mediated signaling |
| negative regulation of production of molecular mediator of immune response |
| regulation of B cell proliferation |
| regulation of antigen receptor-mediated signaling pathway |
| regulation of immunoglobulin production |
| protein phosphatase binding |
| regulation of calcium-mediated signaling |
| recycling endosome |
| negative regulation of immune effector process |
| negative regulation of protein secretion |
| negative regulation of peptide secretion |
| regulation of production of molecular mediator of immune response |
| B cell activation |
| carbohydrate binding |
| negative regulation of protein transport |
| negative regulation of establishment of protein localization |
| negative regulation of secretion by cell |
| regulation of endocytosis |
| regulation of B cell activation |
| regulation of lymphocyte proliferation |
| regulation of mononuclear cell proliferation |
| regulation of leukocyte proliferation |
| negative regulation of secretion |
| early endosome |
| signaling receptor binding |
| lymphocyte activation |
| negative regulation of immune system process |
| regulation of protein secretion |
| regulation of immune effector process |
| negative regulation of transport |
| regulation of peptide secretion |
| negative regulation of intracellular signal transduction |
| regulation of lymphocyte activation |
| regulation of vesicle-mediated transport |
| regulation of leukocyte activation |
| cell surface |
| regulation of cell activation |
| regulation of protein transport |
| regulation of peptide transport |
| regulation of establishment of protein localization |
| regulation of secretion by cell |
| regulation of secretion |
| leukocyte activation |
| cell adhesion |
| biological adhesion |
| regulation of protein localization |
| cell activation |
| regulation of immune response |
| negative regulation of signal transduction |
| negative regulation of cell communication |
| negative regulation of signaling |
| regulation of cell population proliferation |
| negative regulation of response to stimulus |
| regulation of immune system process |
| regulation of intracellular signal transduction |
| regulation of transport |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 8341
- Expression level (log2 read counts): 7.02
Expression Distribution
CD22 Expression in NALM6 Cells: 7.02
