UniProt Summary: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. {ECO:0000250}.
Pfam DomainsGO Terms
Pfam Domains
PMP22 Claudin
GO Terms
calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
tight junction organization
virus receptor activity
viral entry into host cell
entry into host cell
entry into host
bicellular tight junction
cell-cell junction organization
interaction with host
structural molecule activity
viral life cycle
cell junction organization
cell-cell adhesion via plasma-membrane adhesion molecules
cell-cell adhesion
cell junction
intracellular membrane-bounded organelle
viral process
symbiotic process
interspecies interaction between organisms
cell adhesion
biological adhesion
identical protein binding
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)