DGCR6
Gene Information
- Official Symbol: DGCR6
- Official Name: DiGeorge syndrome critical region gene 6
- Aliases and Previous Symbols: N/A
- Entrez ID: 8214
- UniProt: Q14129
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: DiGeorge syndrome, and more widely, the CATCH 22 syndrome, are associated with microdeletions in chromosomal region 22q11.2. The product of this gene shares homology with the Drosophila melanogaster gonadal protein, which participates in gonadal and germ cell development, and with the gamma-1 subunit of human laminin. This gene is a candidate for involvement in DiGeorge syndrome pathology and in schizophrenia. [provided by RefSeq, Nov 2008].
- UniProt Summary: May play a role in neural crest cell migration into the third and fourth pharyngeal pouches.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 6255
- Expression level (log2 read counts): 2.83
DGCR6 Expression in NALM6 Cells: 2.83
